Biochemical and Computational Approaches to Improve the Clinical Treatment of Dopa Decarboxylase-Related Diseases: An Overview

por Cellini, Barbara, Montioli, Riccardo, Oppici, Elisa, Voltattorni, Carla Borri
Publicado 2012

PLP-Dependent Enzymes

por Paiardini, Alessandro, Contestabile, Roberto, Buckle, Ashley M., Cellini, Barbara
Publicado 2014

Oligomeric State and Thermal Stability of Apo- and Holo- Human Ornithine δ-Aminotransferase

por Montioli, Riccardo, Zamparelli, Carlotta, Borri Voltattorni, Carla, Cellini, Barbara
Publicado 2017

Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer–Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina...

por Floriani, Fulvio, Borri Voltattorni, Carla, Cellini, Barbara, Montioli, Riccardo
Publicado 2023

Characterization of C-S Lyase from C. diphtheriae: A Possible Target for New Antimicrobial Drugs

por Astegno, Alessandra, Giorgetti, Alejandro, Allegrini, Alessandra, Cellini, Barbara, Dominici, Paola
Publicado 2013

Editorial: The role of cofactors in protein stability and homeostasis: Focus on human metabolism

por Marchetti, Marialaura, Puglisi, Rita, Cellini, Barbara, Dindo, Mirco, Marchesani, Francesco
Publicado 2023

Interaction of Human Dopa Decarboxylase with L-Dopa: Spectroscopic and Kinetic Studies as a Function of pH

por Montioli, Riccardo, Cellini, Barbara, Dindo, Mirco, Oppici, Elisa, Voltattorni, Carla Borri
Publicado 2013

Biochemical properties and oxalate‐degrading activity of oxalate decarboxylase from bacillus subtilis at neutral pH

por Conter, Carolina, Oppici, Elisa, Dindo, Mirco, Rossi, Luigia, Magnani, Mauro, Cellini, Barbara
Publicado 2019

Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associate...

por Oppici, Elisa, Montioli, Riccardo, Lorenzetto, Antonio, Bianconi, Silvia, Borri Voltattorni, Carla, Cellini, Barbara
Publicado 2012

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis

por Giardina, Giorgio, Paiardini, Alessandro, Montioli, Riccardo, Cellini, Barbara, Voltattorni, Carla Borri, Cutruzzolà, Francesca
Publicado 2017

Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria

por Lage, Melissa D., Pittman, Adrianne M. C., Roncador, Alessandro, Cellini, Barbara, Tucker, Chandra L.
Publicado 2014

Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications

por Oppici, Elisa, Fodor, Krisztian, Paiardini, Alessandro, Williams, Chris, Voltattorni, Carla Borri, Wilmanns, Matthias, Cellini, Barbara
Publicado 2013

Evolutionary Divergent Suppressor Mutations in Conformational Diseases

por Mesa-Torres, Noel, Betancor-Fernández, Isabel, Oppici, Elisa, Cellini, Barbara, Salido, Eduardo, Pey, Angel L.
Publicado 2018

Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism

por Cellini, Barbara, Zelante, Teresa, Dindo, Mirco, Bellet, Marina M., Renga, Giorgia, Romani, Luigina, Costantini, Claudio
Publicado 2020

S81L and G170R mutations causing Primary Hyperoxaluria type I in homozygosis and heterozygosis: an example of positive interallelic complementation

por Montioli, Riccardo, Roncador, Alessandro, Oppici, Elisa, Mandrile, Giorgia, Giachino, Daniela Francesca, Cellini, Barbara, Borri Voltattorni, Carla
Publicado 2014

Molecular and Cellular Studies Reveal Folding Defects of Human Ornithine Aminotransferase Variants Associated With Gyrate Atrophy of the Choroid and Retina

por Montioli, Riccardo, Sgaravizzi, Giada, Desbats, Maria Andrea, Grottelli, Silvia, Voltattorni, Carla Borri, Salviati, Leonardo, Cellini, Barbara
Publicado 2021

Identification of Human Alanine–Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1

por Grottelli, Silvia, Annunziato, Giannamaria, Pampalone, Gioena, Pieroni, Marco, Dindo, Mirco, Ferlenghi, Francesca, Costantino, Gabriele, Cellini, Barbara
Publicado 2022

Identification by Virtual Screening and In Vitro Testing of Human DOPA Decarboxylase Inhibitors

por Daidone, Frederick, Montioli, Riccardo, Paiardini, Alessandro, Cellini, Barbara, Macchiarulo, Antonio, Giardina, Giorgio, Bossa, Francesco, Borri Voltattorni, Carla
Publicado 2012

Crosstalk between Long-Term Sublethal Oxidative Stress and Detrimental Inflammation as Potential Drivers for Age-Related Retinal Degeneration

por Macchioni, Lara, Chiasserini, Davide, Mezzasoma, Letizia, Davidescu, Magdalena, Orvietani, Pier Luigi, Fettucciari, Katia, Salviati, Leonardo, Cellini, Barbara, Bellezza, Ilaria
Publicado 2020

Structural dynamics shape the fitness window of alanine:glyoxylate aminotransferase

por Dindo, Mirco, Pascarelli, Stefano, Chiasserini, Davide, Grottelli, Silvia, Costantini, Claudio, Uechi, Gen‐Ichiro, Giardina, Giorgio, Laurino, Paola, Cellini, Barbara
Publicado 2022