Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function

por Kong, Xaioyuan, Patel, Niketa A., Chalfant, Charles E., Cooper, Denise R.
Publicado 2023

The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x

por Paronetto, Maria Paola, Achsel, Tilman, Massiello, Autumn, Chalfant, Charles E., Sette, Claudio
Publicado 2007

OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2

por West, N Winston, Garcia-Vargas, Aileen, Chalfant, Charles E, Park, Margaret A
Publicado 2013

Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA(2)β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes

por Ali, Tomader, Lei, Xiaoyong, Barbour, Suzanne E., Koizumi, Akio, Chalfant, Charles E., Ramanadham, Sasanka
Publicado 2021

Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting Enzyme

por Lamour, Nadia F., Wijesinghe, Dayanjan S., Mietla, Jennifer A., Ward, Katherine E., Stahelin, Robert V., Chalfant, Charles E.
Publicado 2011

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estrogen, and Glucocorticoid Receptors

por Shaak, Thomas L., Wijesinghe, Dayanjan S., Chalfant, Charles E., Diegelmann, Robert F., Ward, Kevin R., Loria, Roger M.
Publicado 2013

Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts

por Wijesinghe, Dayanjan S., Brentnall, Matthew, Mietla, Jennifer A., Hoeferlin, L. Alexis, Diegelmann, Robert F., Boise, Lawrence H., Chalfant, Charles E.
Publicado 2014

Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

por Kim, Minjung, Vu, Ngoc T., Wang, Xue, Bulut, Gamze B., Wang, Min-Hsuan, Uram-Tuculescu, Cora, Pillappa, Raghavendra, Kim, Sungjune, Chalfant, Charles E.
Publicado 2022

Resolution of Sterile Inflammation: Role for Vitamin C

por Mohammed, Bassem M., Fisher, Bernard J., Huynh, Quoc K., Wijesinghe, Dayanjan S., Chalfant, Charles E., Brophy, Donald F., Fowler III, Alpha A., Natarajan, Ramesh
Publicado 2014

Increased Eicosanoid Levels in the Sugen/Chronic Hypoxia Model of Severe Pulmonary Hypertension

por Al-Husseini, Aysar, Wijesinghe, Dayanjan S., Farkas, Laszlo, Kraskauskas, Donatas, Drake, Jennifer I., Van Tassel, Ben, Abbate, Antonio, Chalfant, Charles E., Voelkel, Norbert F.
Publicado 2015

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α

por Hirano, Yoshinori, Gao, Yong-Guang, Stephenson, Daniel J, Vu, Ngoc T, Malinina, Lucy, Simanshu, Dhirendra K, Chalfant, Charles E, Patel, Dinshaw J, Brown, Rhoderick E
Publicado 2019

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A(2)α

por Hirano, Yoshinori, Gao, Yong-Guang, Stephenson, Daniel J, Vu, Ngoc T, Malinina, Lucy, Simanshu, Dhirendra K, Chalfant, Charles E, Patel, Dinshaw J, Brown, Rhoderick E
Publicado 2021

Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1

por Maus, Kenneth D., Stephenson, Daniel J., Ali, Anika N., MacKnight, Henry Patrick, Huang, Huey-Jing, Serrats, Jordi, Kim, Minjung, Diegelmann, Robert F., Chalfant, Charles E.
Publicado 2022

Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy

por Stephenson, Daniel J., MacKnight, H. Patrick, Hoeferlin, L. Alexis, Washington, Sonya L., Sawyers, Chelsea, Archer, Kellie J., Strauss, Jerome F., Walsh, Scott W., Chalfant, Charles E.
Publicado 2023

Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats

por Spijkers, Léon J. A., Janssen, Ben J. A., Nelissen, Jelly, Meens, Merlijn J. P. M. T., Wijesinghe, Dayanjan, Chalfant, Charles E., De Mey, Jo G. R., Alewijnse, Astrid E., Peters, Stephan L. M.
Publicado 2011

Nonvesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

por Simanshu, Dhirendra K., Kamlekar, Ravi Kanth, Wijesinghe, Dayanjan S., Zou, Xianqiong, Zhai, Xiuhong, Mishra, Shrawan K., Molotkovsky, Julian G., Malinina, Lucy, Hinchcliffe, Edward H., Chalfant, Charles E., Brown, Rhoderick E., Patel, Dinshaw J.
Publicado 2013

Impact of high dose vitamin C on platelet function

por Mohammed, Bassem M, Sanford, Kimberly W, Fisher, Bernard J, Martin, Erika J, Contaifer Jr, Daniel, Warncke, Urszula Osinska, Wijesinghe, Dayanjan S, Chalfant, Charles E, Brophy, Donald F, Fowler III, Alpha A, Natarajan, Ramesh
Publicado 2017

A Novel Model of Chronic Wounds: Importance of Redox Imbalance and Biofilm-Forming Bacteria for Establishment of Chronicity

por Dhall, Sandeep, Do, Danh, Garcia, Monika, Wijesinghe, Dayanjan Shanaka, Brandon, Angela, Kim, Jane, Sanchez, Antonio, Lyubovitsky, Julia, Gallagher, Sean, Nothnagel, Eugene A., Chalfant, Charles E., Patel, Rakesh P., Schiller, Neal, Martins-Green, Manuela
Publicado 2014

Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens

por Cockburn, Chelsea L, Green, Ryan S, Damle, Sheela R, Martin, Rebecca K, Ghahrai, Naomi N, Colonne, Punsiri M, Fullerton, Marissa S, Conrad, Daniel H, Chalfant, Charles E, Voth, Daniel E, Rucks, Elizabeth A, Gilk, Stacey D, Carlyon, Jason A
Publicado 2019

Lipid mediators and biomarkers associated with type 1 diabetes development

por Nelson, Alexander J., Stephenson, Daniel J., Bone, Robert N., Cardona, Christopher L., Park, Margaret A., Tusing, Ying G., Lei, Xiaoyong, Kokotos, George, Graves, Christina L., Mathews, Clayton E., Kramer, Joanna, Hessner, Martin J., Chalfant, Charles E., Ramanadham, Sasanka
Publicado 2020