A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation

por Besancenot, Rodolphe, Chaligné, Ronan, Tonetti, Carole, Pasquier, Florence, Marty, Caroline, Lécluse, Yann, Vainchenker, William, Constantinescu, Stefan N., Giraudier, Stéphane
Publicado 2010

Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders

por Shah, Ruth R., Cholewa-Waclaw, Justyna, Davies, Faith C.J., Paton, Katie M., Chaligne, Ronan, Heard, Edith, Abbott, Catherine M., Bird, Adrian P.
Publicado 2016

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

por Cantone, Irene, Bagci, Hakan, Dormann, Dirk, Dharmalingam, Gopuraja, Nesterova, Tatyana, Brockdorff, Neil, Rougeulle, Claire, Vallot, Celine, Heard, Edith, Chaligne, Ronan, Merkenschlager, Matthias, Fisher, Amanda G.
Publicado 2016

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

por Chaligné, Ronan, Popova, Tatiana, Mendoza-Parra, Marco-Antonio, Saleem, Mohamed-Ashick M., Gentien, David, Ban, Kristen, Piolot, Tristan, Leroy, Olivier, Mariani, Odette, Gronemeyer, Hinrich, Vincent-Salomon, Anne, Stern, Marc-Henri, Heard, Edith
Publicado 2015

Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer

por Zhang, Haochen, Karnoub, Elias-Ramzey, Umeda, Shigeaki, Chaligné, Ronan, Masilionis, Ignas, McIntyre, Caitlin A., Sashittal, Palash, Hayashi, Akimasa, Zucker, Amanda, Mullen, Katelyn, Hong, Jungeui, Makohon-Moore, Alvin, Iacobuzio-Donahue, Christine A.
Publicado 2023

MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis

por Barriga, Francisco M., Tsanov, Kaloyan M., Ho, Yu-Jui, Sohail, Noor, Zhang, Amy, Baslan, Timour, Wuest, Alexandra N., Del Priore, Isabella, Meškauskaitė, Brigita, Livshits, Geulah, Alonso-Curbelo, Direna, Simon, Janelle, Chaves-Perez, Almudena, Bar-Sagi, Dafna, Iacobuzio-Donahue, Christine A., Notta, Faiyaz, Chaligne, Ronan, Sharma, Roshan, Pe’er, Dana, Lowe, Scott W.
Publicado 2022

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

por Burdziak, Cassandra, Alonso-Curbelo, Direna, Walle, Thomas, Reyes, José, Barriga, Francisco M., Haviv, Doron, Xie, Yubin, Zhao, Zhen, Zhao, Chujun Julia, Chen, Hsuan-An, Chaudhary, Ojasvi, Masilionis, Ignas, Choo, Zi-Ning, Gao, Vianne, Luan, Wei, Wuest, Alexandra, Ho, Yu-Jui, Wei, Yuhong, Quail, Daniela F, Koche, Richard, Mazutis, Linas, Chaligné, Ronan, Nawy, Tal, Lowe, Scott W., Pe’er, Dana
Publicado 2023

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

por Pastore, Alessandro, Gaiti, Federico, Lu, Sydney X., Brand, Ryan M., Kulm, Scott, Chaligne, Ronan, Gu, Hongcang, Huang, Kevin Y., Stamenova, Elena K., Béguelin, Wendy, Jiang, Yanwen, Schulman, Rafael C., Kim, Kyu-Tae, Alonso, Alicia, Allan, John N., Furman, Richard R., Gnirke, Andreas, Wu, Catherine J., Melnick, Ari M., Meissner, Alexander, Bernstein, Bradley E., Abdel-Wahab, Omar, Landau, Dan A.
Publicado 2019

Genotyping of Transcriptomes links somatic mutations and cell identity

por Nam, Anna S., Kim, Kyu-Tae, Chaligne, Ronan, Izzo, Franco, Ang, Chelston, Taylor, Justin, Myers, Robert M., Abu-Zeinah, Ghaith, Brand, Ryan, Omans, Nathaniel D., Alonso, Alicia, Sheridan, Caroline, Mariani, Marisa, Dai, Xiaoguang, Harrington, Eoghan, Pastore, Alessandro, Cubillos-Ruiz, Juan R., Tam, Wayne, Hoffman, Ronald, Rabadan, Raul, Scandura, Joseph M., Abdel-Wahab, Omar, Smibert, Peter, Landau, Dan A.
Publicado 2019

DNA methylation disruption reshapes the hematopoietic differentiation landscape

por Izzo, Franco, Lee, Stanley C., Poran, Asaf, Chaligne, Ronan, Gaiti, Federico, Gross, Baptiste, Murali, Rekha R., Deochand, Sunil D., Ang, Chelston, Jones, Philippa Wyndham, Nam, Anna S., Kim, Kyu-Tae, Kothen-Hill, Steven, Schulman, Rafael C., Ki, Michelle, Lhoumaud, Priscillia, Skok, Jane A., Viny, Aaron D., Levine, Ross L., Kenigsberg, Ephraim, Abdel-Wahab, Omar, Landau, Dan A.
Publicado 2020

Epigenetic evolution and lineage histories of chronic lymphocytic leukemia

por Gaiti, Federico, Chaligne, Ronan, Gu, Hongcang, Brand, Ryan Matthew, Kothen-Hill, Steven, Schulman, Rafael, Grigorev, Kirill, Risso, Davide, Kim, Kyu-Tae, Pastore, Alessandro, Huang, Kevin Y., Alonso, Alicia, Sheridan, Caroline, Omans, Nathaniel D., Biederstedt, Evan, Clement, Kendell, Wang, Lili, Felsenfeld, Joshua A., Bhavsar, Erica B., Aryee, Martin J., Allan, John N., Furman, Richard, Gnirke, Andreas, Wu, Catherine J., Meissner, Alexander, Landau, Dan A.
Publicado 2019