Regulation of cyclic AMP response-element binding-protein (CREB) by G(q/11)-protein-coupled receptors in human SH-SY5Y neuroblastoma cells

por Rosethorne, Elizabeth M., Nahorski, Stefan R., Challiss, R.A. John
Publicado 2008

Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated s...

por Nelson, Carl P, Nahorski, Stefan R, Challiss, R A John
Publicado 2008

The regulation of M(1) muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neurons

por Willets, Jonathon M, Nelson, Carl P, Nahorski, Stefan R, Challiss, R A John
Publicado 2007

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

por Morris, Gavin E., Nelson, Carl P., Standen, Nicholas B., Challiss, R.A. John, Willets, Jonathon M.
Publicado 2010

Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension

por Willets, Jonathon M., Nash, Craig A., Rainbow, Richard D., Nelson, Carl P., Challiss, R. A. John
Publicado 2015

FRET-Based Detection of M(1) Muscarinic Acetylcholine Receptor Activation by Orthosteric and Allosteric Agonists

por Markovic, Danijela, Holdich, Jonathan, Al-Sabah, Suleiman, Mistry, Rajendra, Krasel, Cornelius, Mahaut-Smith, Martyn P., Challiss, R. A. John
Publicado 2012

Steady-State Modulation of Voltage-Gated K(+) Channels in Rat Arterial Smooth Muscle by Cyclic AMP-Dependent Protein Kinase and Protein Phosphatase 2B

por Brignell, Jennifer L., Perry, Matthew D., Nelson, Carl P., Willets, Jonathon M., Challiss, R. A. John, Davies, Noel W.
Publicado 2015

G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

por Morris, Gavin E., Nelson, Carl P., Everitt, Diane, Brighton, Paul J., Standen, Nicholas B., Challiss, R.A. John, Willets, Jonathon M.
Publicado 2011

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

por Di Candia, Leonarda, Gomez, Edith, Venereau, Emilie, Chachi, Latifa, Kaur, Davinder, Bianchi, Marco E., Challiss, R.A. John, Brightling, Christopher E., Saunders, Ruth M.
Publicado 2017

Principal role of adenylyl cyclase 6 in K(+) channel regulation and vasodilator signalling in vascular smooth muscle cells

por Nelson, Carl P., Rainbow, Richard D., Brignell, Jennifer L., Perry, Matthew D., Willets, Jonathon M., Davies, Noel W., Standen, Nicholas B., Challiss, R.A. John
Publicado 2011

Regulation of Neuronal Plasticity and Fear by a Dynamic Change in PAR1 – G Protein Coupling in the Amygdala

por Bourgognon, Julie-Myrtille, Schiavon, Emanuele, Salah-Uddin, Hasib, Skrzypiec, Anna E., Attwood, Benjamin K., Shah, Rahul S., Patel, Satyam G., Mucha, Mariusz, Challiss, R. A. John, Forsythe, Ian D., Pawlak, Robert
Publicado 2012

An Antibody Biosensor Establishes the Activation of the M(1) Muscarinic Acetylcholine Receptor during Learning and Memory

por Butcher, Adrian J., Bradley, Sophie J., Prihandoko, Rudi, Brooke, Simon M., Mogg, Adrian, Bourgognon, Julie-Myrtille, Macedo-Hatch, Timothy, Edwards, Jennifer M., Bottrill, Andrew R., Challiss, R. A. John, Broad, Lisa M., Felder, Christian C., Tobin, Andrew B.
Publicado 2016

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

por Robinson, Susan W., Bourgognon, Julie-Myrtille, Spiers, Jereme G., Breda, Carlo, Campesan, Susanna, Butcher, Adrian, Mallucci, Giovanna R., Dinsdale, David, Morone, Nobuhiro, Mistry, Raj, Smith, Tim M., Guerra-Martin, Maria, Challiss, R. A. John, Giorgini, Flaviano, Steinert, Joern R.
Publicado 2018

Clustered Coding Variants in the Glutamate Receptor Complexes of Individuals with Schizophrenia and Bipolar Disorder

por Frank, René A. W., McRae, Allan F., Pocklington, Andrew J., van de Lagemaat, Louie N., Navarro, Pau, Croning, Mike D. R., Komiyama, Noboru H., Bradley, Sophie J., Challiss, R. A. John, Armstrong, J. Douglas, Finn, Robert D., Malloy, Mary P., MacLean, Alan W., Harris, Sarah E., Starr, John M., Bhaskar, Sanjeev S., Howard, Eleanor K., Hunt, Sarah E., Coffey, Alison J., Ranganath, Venkatesh, Deloukas, Panos, Rogers, Jane, Muir, Walter J., Deary, Ian J., Blackwood, Douglas H., Visscher, Peter M., Grant, Seth G. N.
Publicado 2011