Granulocyte-macrophage colony stimulating factor in COVID-19: friend or foe?

por Mehta, Puja, Chambers, Rachel C, Dagna, Lorenzo
Publicado 2021

The promise of mTOR as a therapeutic target pathway in idiopathic pulmonary fibrosis

por Platé, Manuela, Guillotin, Delphine, Chambers, Rachel C
Publicado 2020

Cell–matrix interactions in lung disease and regeneration: ERS Lung Science Conference 2018 report

por Meiners, Silke, Lloyd, Clare, Chambers, Rachel C.
Publicado 2018

Novel therapeutic approaches for pulmonary fibrosis

por Datta, Arnab, Scotton, Chris J, Chambers, Rachel C
Publicado 2011

Mechanistic overlap between chronic lung injury and cancer: ERS Lung Science Conference 2017 report

por Gosens, Reinoud, Giangreco, Adam, Sahai, Erik, Chambers, Rachel C.
Publicado 2017

Enhanced inflammation in aged mice following infection with Streptococcus pneumoniae is associated with decreased IL-10 and augmented chemokine production

por Williams, Andrew E., José, Ricardo J., Brown, Jeremy S., Chambers, Rachel C.
Publicado 2015

JAK inhibitors in COVID-19: the need for vigilance regarding increased inherent thrombotic risk

por Mehta, Puja, Ciurtin, Coziana, Scully, Marie, Levi, Marcel, Chambers, Rachel C.
Publicado 2020

Targeting coagulation activation in severe COVID-19 pneumonia: lessons from bacterial pneumonia and sepsis

por José, Ricardo J., Williams, Andrew, Manuel, Ari, Brown, Jeremy S., Chambers, Rachel C.
Publicado 2020

B-cell depletion with rituximab in the COVID-19 pandemic: where do we stand?

por Mehta, Puja, Porter, Joanna C, Chambers, Rachel C, Isenberg, David A, Reddy, Venkat
Publicado 2020

Thromboses and COVID-19: reducing inflammation in addition to thromboprophylaxis

por Mehta, Puja, Haskard, Dorian O, Laffan, Michael A, Chambers, Rachel C, Hunt, Beverley J
Publicado 2021

Manipulating the natriuretic peptide system for the treatment of pulmonary hypertension

por Baliga, Reshma S, Trinder, Sarah, Scotton, Chris J, Chambers, Rachel C, MacAllister, Raymond J, Hobbs, Adrian J
Publicado 2009

Regulation of Neutrophilic Inflammation by Proteinase-Activated Receptor 1 during Bacterial Pulmonary Infection

por José, Ricardo J., Williams, Andrew E., Mercer, Paul F., Sulikowski, Michal G., Brown, Jeremy S., Chambers, Rachel C.
Publicado 2015

Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1–dependent leukocyte recruitment in vivo

por Chen, Daxin, Carpenter, Adam, Abrahams, Joel, Chambers, Rachel C., Lechler, Robert I., McVey, John H., Dorling, Anthony
Publicado 2008

Enhancing natriuretic peptide bioactivity prevents bleomycin-induced pulmonary fibrosis

por Baliga, Reshma S, Trinder, Sarah L, Scotton, Christopher J, Chambers, Rachel C, MacAllister, Raymond J, Hobbs, Adrian J
Publicado 2011

Cancer patients with community-acquired pneumonia treated in intensive care have poorer outcomes associated with increased illness severity and septic shock at admission to intensi...

por José, Ricardo J. P., Mohammed, Ali O., Goldring, James J. P., Chambers, Rachel C., Brown, Jeremy S., Agarwal, Banwari
Publicado 2015

Influenza vaccination and interruption of methotrexate in adult patients in the COVID-19 era: an ongoing dilemma

por Mehta, Puja, Sanchez, Emilie, Moraitis, Elena, Longley, Nicky, Lendrem, Dennis W, Giles, Ian P, Chambers, Rachel C, Ciurtin, Coziana, Isaacs, John D
Publicado 2021

The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection

por Smoktunowicz, Natalia, Alexander, Robert E., Franklin, Linda, Williams, Andrew E., Holman, Beverley, Mercer, Paul F., Jarai, Gabor, Scotton, Chris J., Chambers, Rachel C.
Publicado 2015

TGFβ upregulates PAR-1 expression and signalling responses in A549 lung adenocarcinoma cells

por Smoktunowicz, Natalia, Platé, Manuela, Stern, Alejandro Ortiz, D'Antongiovanni, Vanessa, Robinson, Eifion, Chudasama, Vijay, Caddick, Stephen, Scotton, Chris J., Jarai, Gabor, Chambers, Rachel C.
Publicado 2016

Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities

por Mehta, Puja, Porter, Joanna C, Manson, Jessica J, Isaacs, John D, Openshaw, Peter J M, McInnes, Iain B, Summers, Charlotte, Chambers, Rachel C
Publicado 2020

Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages

por Kallis, Yiannis N., Scotton, Christopher J., MacKinnon, Alison C., Goldin, Robert D., Wright, Nicholas A., Iredale, John P., Chambers, Rachel C., Forbes, Stuart J.
Publicado 2014