Classification of Protein-Binding Sites Using a Spherical Convolutional Neural Network

por Scott, Oliver B., Gu, Jing, Chan, A.W. Edith
Publicado 2022

Benzobisthiazoles Represent a Novel Scaffold for Kinase Inhibitors of CLK Family Members

por Prak, Krisna, Kriston-Vizi, Janos, Chan, A. W. Edith, Luft, Christin, Costa, Joana R., Pengo, Niccolo, Ketteler, Robin
Publicado 2015

LigSearch: a knowledge-based web server to identify likely ligands for a protein target

por de Beer, Tjaart A. P., Laskowski, Roman A., Duban, Mark-Eugene, Chan, A. W. Edith, Anderson, Wayne F., Thornton, Janet M.
Publicado 2013

N(10)‐carbonyl‐substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress

por Keynes, Robert G., Karchevskaya, Anastasia, Riddall, Dieter, Griffiths, Charmaine H., Bellamy, Tomas C., Chan, A. W. Edith, Selwood, David L., Garthwaite, John
Publicado 2019

Imidazol-1-ylethylindazole Voltage-Gated Sodium Channel Ligands Are Neuroprotective during Optic Neuritis in a Mouse Model of Multiple Sclerosis

por Browne, Lorcan, Lidster, Katie, Al-Izki, Sarah, Clutterbuck, Lisa, Posada, Cristina, Chan, A. W. Edith, Riddall, Dieter, Garthwaite, John, Baker, David, Selwood, David L.
Publicado 2014

Correction to Imidazol-1-ylethylindazole Voltage-Gated Sodium Channel Ligands Are Neuroprotective during Optic Neuritis in a Mouse Model of Multiple Sclerosis

por Browne, Lorcan, Lidster, Katie, Al-Izki, Sarah, Clutterbuck, Lisa, Posada, Cristina, Chan, A. W. Edith, Riddall, Dieter, Garthwaite, John, Baker, David, Selwood, David L.
Publicado 2015

Suppression of type 1 pilus assembly in uropathogenic Escherichia coli by chemical inhibition of subunit polymerization

por Lo, Alvin W. H., Van de Water, Karen, Gane, Paul J., Chan, A.W. Edith, Steadman, David, Stevens, Kiri, Selwood, David L., Waksman, Gabriel, Remaut, Han
Publicado 2014

In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors

por Guo, Jingxu, Douangamath, Alice, Song, Weixiao, Coker, Alun R., Chan, A.W. Edith, Wood, Steve P., Cooper, Jonathan B., Resnick, Efrat, London, Nir, Delft, Frank von
Publicado 2020

IKKγ-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection

por Briggs, Louise C., Chan, A. W. Edith, Davis, Christopher A., Whitelock, Nicholas, Hotiana, Hajira A., Baratchian, Mehdi, Bagnéris, Claire, Selwood, David L., Collins, Mary K., Barrett, Tracey E.
Publicado 2017

Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells

por Pengo, Niccolo, Prak, Krisna, Costa, Joana R., Luft, Christin, Agrotis, Alexander, Freeman, Jamie, Gewinner, Christina A., Chan, A. W. Edith, Selwood, David L., Kriston-Vizi, Janos, Ketteler, Robin
Publicado 2018

Architecture and hydration of the arginine‐binding site of neuropilin‐1

por Mota, Filipa, Fotinou, Constantina, Rana, Rohini R., Chan, A. W. Edith, Yelland, Tamas, Arooz, Mohamed T., O'Leary, Andrew P., Hutton, Jennie, Frankel, Paul, Zachary, Ian, Selwood, David, Djordjevic, Snezana
Publicado 2018

Therapeutic Validation of GEF-H1 Using a De Novo Designed Inhibitor in Models of Retinal Disease

por Mills, Clare, Hemkemeyer, Sandra A., Alimajstorovic, Zerin, Bowers, Chantelle, Eskandarpour, Malihe, Greenwood, John, Calder, Virginia, Chan, A. W. Edith, Gane, Paul J., Selwood, David L., Matter, Karl, Balda, Maria S.
Publicado 2022

Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin‐1

por Mota, Filipa, Yelland, Tamas, Hutton, Jennie A., Parker, Jennifer, Patsiarika, Anastasia, Chan, A. W. Edith, O'Leary, Andrew, Fotinou, Constantina, Martin, John F., Zachary, Ian C., Djordjevic, Snezana, Frankel, Paul, Selwood, David L.
Publicado 2021

Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis

por Warne, Justin, Pryce, Gareth, Hill, Julia M., Shi, Xiao, Lennerås, Felicia, Puentes, Fabiola, Kip, Maarten, Hilditch, Laura, Walker, Paul, Simone, Michela I., Chan, A. W. Edith, Towers, Greg J., Coker, Alun R., Duchen, Michael R., Szabadkai, Gyorgy, Baker, David, Selwood, David L.
Publicado 2016

Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGFβ) Production...

por Powell, Jonathan, Mota, Filipa, Steadman, David, Soudy, Christelle, Miyauchi, Jeremy T., Crosby, Stuart, Jarvis, Ashley, Reisinger, Tifelle, Winfield, Natalie, Evans, Graham, Finniear, Aled, Yelland, Tamas, Chou, Yi-Tai, Chan, A.W. Edith, O’Leary, Andrew, Cheng, Lili, Liu, Dan, Fotinou, Constantina, Milagre, Carla, Martin, John F., Jia, Haiyan, Frankel, Paul, Djordjevic, Snezana, Tsirka, Stella E., Zachary, Ian C, Selwood, David L.
Publicado 2018