Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions

por Chan, Anthony K. N., Chen, Chun-Wei
Publicado 2019

Concise and Stereodivergent Synthesis of Carbasugars Reveals Unexpected Structure-Activity Relationship (SAR) of SGLT2 Inhibition

por Ng, Wai-Lung, Li, Ho-Chuen, Lau, Kit-Man, Chan, Anthony K. N., Lau, Clara Bik-San, Shing, Tony K. M.
Publicado 2017

Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications

por Kumar, Anil, Lee, Sung June, Liu, Qiao, Chan, Anthony K.N., Pokharel, Sheela Pangeni, Yu, Jianhua, Chen, Chun-Wei, Swaminathan, Srividya
Publicado 2021

3-Ketodihydrosphingosine reductase maintains ER homeostasis and unfolded protein response in leukemia

por Liu, Qiao, Chan, Anthony K.N., Chang, Wen-Han, Yang, Lu, Pokharel, Sheela Pangeni, Miyashita, Kazuya, Mattson, Nicole, Xu, Xiaobao, Li, Mingli, Lu, Wei, Lin, Ren-Jang, Wang, Shao-Yuan, Chen, Chun-Wei
Publicado 2021

ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner

por Xu, Xiaobao, Chan, Anthony K. N., Li, Mingli, Liu, Qiao, Mattson, Nicole, Pangeni Pokharel, Sheela, Chang, Wen-Han, Yuan, Yate-Ching, Wang, Jinhui, Moore, Roger E., Pirrotte, Patrick, Wu, Jun, Su, Rui, Müschen, Markus, Rosen, Steven T., Chen, Jianjun, Yang, Lu, Chen, Chun-Wei
Publicado 2022

Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System

por Pliotas, Christos, Grayer, Samuel C., Ekkerman, Silvia, Chan, Anthony K. N., Healy, Jess, Marius, Phedra, Bartlett, Wendy, Khan, Amjad, Cortopassi, Wilian A., Chandler, Shane A., Rasmussen, Tim, Benesch, Justin L. P., Paton, Robert S., Claridge, Timothy D. W., Miller, Samantha, Booth, Ian R., Naismith, James H., Conway, Stuart J.
Publicado 2017

Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

por Li, Mingli, Yang, Lu, Chan, Anthony K. N., Pokharel, Sheela Pangeni, Liu, Qiao, Mattson, Nicole, Xu, Xiaobao, Chang, Wen‐Han, Miyashita, Kazuya, Singh, Priyanka, Zhang, Leisi, Li, Maggie, Wu, Jun, Wang, Jinhui, Chen, Bryan, Chan, Lai N., Lee, Jaewoong, Zhang, Xu Hannah, Rosen, Steven T., Müschen, Markus, Qi, Jun, Chen, Jianjun, Hiom, Kevin, Bishop, Alexander J. R., Chen, Chun‐Wei
Publicado 2023

High-resolution characterization of gene function using single-cell CRISPR tiling screen

por Yang, Lu, Chan, Anthony K. N., Miyashita, Kazuya, Delaney, Christopher D., Wang, Xi, Li, Hongzhi, Pokharel, Sheela Pangeni, Li, Sandra, Li, Mingli, Xu, Xiaobao, Lu, Wei, Liu, Qiao, Mattson, Nicole, Chen, Kevin Yining, Wang, Jinhui, Yuan, Yate-Ching, Horne, David, Rosen, Steven T., Soto-Feliciano, Yadira, Feng, Zhaohui, Hoshii, Takayuki, Xiao, Gang, Müschen, Markus, Chen, Jianjun, Armstrong, Scott A., Chen, Chun-Wei
Publicado 2021

Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain

por Brand, Michael, Clayton, James, Moroglu, Mustafa, Schiedel, Matthias, Picaud, Sarah, Bluck, Joseph P., Skwarska, Anna, Bolland, Hannah, Chan, Anthony K. N., Laurin, Corentine M. C., Scorah, Amy R., See, Larissa, Rooney, Timothy P. C., Andrews, Katrina H., Fedorov, Oleg, Perell, Gabriella, Kalra, Prakriti, Vinh, Kayla B., Cortopassi, Wilian A., Heitel, Pascal, Christensen, Kirsten E., Cooper, Richard I., Paton, Robert S., Pomerantz, William C. K., Biggin, Philip C., Hammond, Ester M., Filippakopoulos, Panagis, Conway, Stuart J.
Publicado 2021

Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir

por Lo, Ho Sing, Hui, Kenrie Pui Yan, Lai, Hei-Ming, He, Xu, Khan, Khadija Shahed, Kaur, Simranjeet, Huang, Junzhe, Li, Zhongqi, Chan, Anthony K. N., Cheung, Hayley Hei-Yin, Ng, Ka-Chun, Ho, John Chi Wang, Chen, Yu Wai, Ma, Bowen, Cheung, Peter Man-Hin, Shin, Donghyuk, Wang, Kaidao, Lee, Meng-Hsuan, Selisko, Barbara, Eydoux, Cecilia, Guillemot, Jean-Claude, Canard, Bruno, Wu, Kuen-Phon, Liang, Po-Huang, Dikic, Ivan, Zuo, Zhong, Chan, Francis K. L., Hui, David S. C., Mok, Vincent C. T., Wong, Kam-Bo, Mok, Chris Ka Pun, Ko, Ho, Aik, Wei Shen, Chan, Michael Chi Wai, Ng, Wai-Lung
Publicado 2021