Tackling Cancer Stem Cells via Inhibition of EMT Transcription Factors

por Mladinich, Megan, Ruan, Diane, Chan, Chia-Hsin
Publicado 2016

HectH9 hijacks glucose metabolism to fuel tumor growth

por Lee, Hong-Jen, He, Jiabei, Chan, Chia-Hsin
Publicado 2019

Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis

por Wang, Guocan, Chan, Chia-Hsin, Gao, Yuan, Lin, Hui-Kuan
Publicado 2012

Skp2: A dream target in the coming age of cancer therapy

por Chan, Chia-Hsin, Morrow, John Kenneth, Zhang, Shuxing, Lin, Hui-Kuan
Publicado 2014

Regulation of Skp2 Expression and Activity and Its Role in Cancer Progression

por Chan, Chia-Hsin, Lee, Szu-Wei, Wang, Jing, Lin, Hui-Kuan
Publicado 2010

The ubiquitin ligase RNF8 regulates Rho GTPases and promotes cytoskeletal changes and motility in triple‐negative breast cancer cells

por Pereira De Carvalho, Bruno, Chern, Yi‐Jye, He, Jiabei, Chan, Chia‐Hsin
Publicado 2020

Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy

por He, Jiabei, Lee, Hong-Jen, Saha, Suchandrima, Ruan, Diane, Guo, Hua, Chan, Chia-Hsin
Publicado 2019

Posttranslational regulation of Akt in human cancer

por Chan, Chia-Hsin, Jo, Ukhyun, Kohrman, Abraham, Rezaeian, Abdol Hossein, Chou, Ping-Chieh, Logothetis, Christopher, Lin, Hui-Kuan
Publicado 2014

Skp2 deficiency restricts the progression and stem cell features of castration-resistant prostate cancer by destabilizing Twist

por Ruan, Diane, He, Jiabei, Li, Chien-Feng, Lee, Hong-Jen, Liu, Jingxuan, Lin, Hui-Kuan, Chan, Chia-Hsin
Publicado 2017

The Oxygen-Generating Calcium Peroxide-Modified Magnetic Nanoparticles Attenuate Hypoxia-Induced Chemoresistance in Triple-Negative Breast Cancer

por Cheng, Fong-Yu, Chan, Chia-Hsin, Wang, Bour-Jr, Yeh, Ya-Ling, Wang, Ying-Jan, Chiu, Hui-Wen
Publicado 2021

Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion

por Lee, Hong-Jen, Li, Chien-Feng, Ruan, Diane, He, Jiabei, Montal, Emily D., Lorenz, Sonja, Girnun, Geoffrey D., Chan, Chia-Hsin
Publicado 2019

MIG‐6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple‐negative breast cancer

por He, Jiabei, Li, Chien‐Feng, Lee, Hong‐Jen, Shin, Dong‐Hui, Chern, Yi‐Jye, Pereira De Carvalho, Bruno, Chan, Chia‐Hsin
Publicado 2021

Nonmonotone invasion landscape by noise-aware control of metastasis activator levels

por Wan, Yiming, Cohen, Joseph, Szenk, Mariola, Farquhar, Kevin S., Coraci, Damiano, Krzysztoń, Rafał, Azukas, Joshua, Van Nest, Nicholas, Smashnov, Alex, Chern, Yi-Jye, De Martino, Daniela, Nguyen, Long Chi, Bien, Harold, Bravo-Cordero, Jose Javier, Chan, Chia-Hsin, Rosner, Marsha Rich, Balázsi, Gábor
Publicado 2023

Skp2-MacroH2A1-CDK8 axis orchestrates G2/M transition, polyploidy and tumourigenesis

por Xu, Dazhi, Li, Chien-Feng, Zhang, Xian, Gong, Zhaohui, Chan, Chia-Hsin, Lee, Szu-Wei, Jin, Guoxiang, Rezaeian, Abdol-Hossein, Han, Fei, Wang, Jing, Yang, Wei-Lei, Feng, Zi-Zhen, Chen, Wei, Wu, Ching-Yuan, Wang, Ying-Jan, Chow, Lu-Ping, Zhu, Xiao-Feng, Zeng, Yi-Xin, Lin, Hui-Kuan
Publicado 2015