Formulation of a kit under Good Manufacturing Practices (GMP) for preparing [(111)In]In-BnDTPA-trastuzumab-NLS injection: a theranostic agent for imaging and Meitner-Auger Electron...

por Chan, Conrad, Prozzo, Vanessa, Aghevlian, Sadaf, Reilly, Raymond M.
Publicado 2022

[(225)Ac]Ac- and [(111)In]In-DOTA-trastuzumab theranostic pair: cellular dosimetry and cytotoxicity in vitro and tumour and normal tissue uptake in vivo in NRG mice with HER2-posit...

por Kondo, Misaki, Cai, Zhongli, Chan, Conrad, Forkan, Nubaira, Reilly, Raymond M.
Publicado 2023

A comparison of (111)In- or (64)Cu-DOTA-trastuzumab Fab fragments for imaging subcutaneous HER2-positive tumor xenografts in athymic mice using microSPECT/CT or microPET/CT

por Chan, Conrad, Scollard, Deborah A, McLarty, Kristin, Smith, Serena, Reilly, Raymond M
Publicado 2011

Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic i...

por Chan, Conrad E.Z., Chan, Annie H.Y., Lim, Angeline P.C., Hanson, Brendon J.
Publicado 2011

The Molecular Engineering of an Anti-Idiotypic Antibody for Pharmacokinetic Analysis of a Fully Human Anti-Infective

por Lim, She Yah, Chan, Conrad E. Z., Lisowska, Malgorzata M., Hanson, Brendon J., MacAry, Paul A.
Publicado 2015

Epitope characterization of the protective monoclonal antibody VN04-2 shows broadly neutralizing activity against highly pathogenic H5N1

por Lim, Angeline PC, Wong, Steven KK, Chan, Annie HY, Chan, Conrad EZ, Ooi, Eng Eong, Hanson, Brendon J
Publicado 2008

Neutralizing human monoclonal antibody against H5N1 influenza HA selected from a Fab-phage display library

por Lim, Angeline PC, Chan, Conrad EZ, Wong, Steven KK, Chan, Annie HY, Ooi, Eng Eong, Hanson, Brendon J
Publicado 2008

Optimized Expression of Full-Length IgG1 Antibody in a Common E. coli Strain

por Chan, Conrad En Zuo, Lim, Angeline Pei Chiew, Chan, Annie Hoi Yi, MacAry, Paul A., Hanson, Brendon John
Publicado 2010

The diagnostic targeting of a carbohydrate virulence factor from M.Tuberculosis

por Chan, Conrad E., Götze, Sebastian, Seah, Geok T., Seeberger, Peter H., Tukvadze, Nestan, Wenk, Markus R., Hanson, Brendon J., MacAry, Paul A.
Publicado 2015

Generation and Characterization of a Novel Recombinant Antibody Against 15-Ketocholestane Isolated by Phage-Display

por Islam, Md. Omedul, Lim, Yan Ting, Chan, Conrad En Zuo, Cazenave-Gassiot, Amaury, Croxford, J. Ludovic, Wenk, Markus R., Macary, Paul A., Hanson, Brendon J.
Publicado 2012

Chinese herbal medicine treatment based on subgroup differentiation as adjunct therapy for Parkinson’s disease: study protocol of a pilot add-on, randomised, controlled, pragmatic...

por Yuen, Sam Chun Sum, Chua, Ka Kit, Zhong, Linda L. D., Chan, Kam Wa, Chan, Conrad Kwan Ho, Chan, Kam Leung, Lin, Zhixiu, Mok, Vincent, Lau, Alexander Y., Li, Min
Publicado 2022

Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells

por Park, Hae-Young, Tan, Peck S., Kavishna, Ranmali, Ker, Anna, Lu, Jinhua, Chan, Conrad E. Z., Hanson, Brendon J., MacAry, Paul A., Caminschi, Irina, Shortman, Ken, Alonso, Sylvie, Lahoud, Mireille H.
Publicado 2017

Defining the specificity and function of a human neutralizing antibody for Hepatitis B virus

por Jhajharia, Saket, Lai, Fritz, Low, Heng Boon, Purushotorman, Kiren, Shunmuganathan, Bhuvaneshwari D/O, Chan, Conrad En Zuo, Hammond, Rachel, Netter, Hans-Jürgen, Chen, Qingfeng, Lim, Seng Gee, MacAry, Paul A.
Publicado 2022

IDentif.AI: Rapidly optimizing combination therapy design against severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐Cov‐2) with digital drug development

por Blasiak, Agata, Lim, Jhin Jieh, Seah, Shirley Gek Kheng, Kee, Theodore, Remus, Alexandria, Chye, De Hoe, Wong, Pui San, Hooi, Lissa, Truong, Anh T. L., Le, Nguyen, Chan, Conrad E. Z., Desai, Rishi, Ding, Xianting, Hanson, Brendon J., Chow, Edward Kai‐Hua, Ho, Dean
Publicado 2020

TCR–like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus–transformed B lymphoblastoid cells expressing different HLA-A*02 micr...

por Lai, Junyun, Choo, Joanna Ai Ling, Tan, Wei Jian, Too, Chien Tei, Oo, Min Zin, Suter, Manuel A., Mustafa, Fatimah Bte, Srinivasan, Nalini, Chan, Conrad En Zuo, Lim, Andrew Guo Xian, Zhong, Youjia, Chan, Soh Ha, Hanson, Brendon J., Gascoigne, Nicholas R. J., MacAry, Paul A.
Publicado 2017

The Cellular Characterization of SARS-CoV-2 Spike Protein in Virus-Infected Cells Using the Receptor Binding Domain Binding Specific Human Monoclonal Antibodies

por Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon-Huan
Publicado 2022

An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis

por Krishnananthasivam, Shivankari, Li, Hao, Bouzeyen, Rania, Shunmuganathan, Bhuvaneshwari, Purushotorman, Kiren, Liao, Xinlei, Du, Fengjiao, Friis, Claudia Guldager Kring, Crawshay-Williams, Felicity, Boon, Low Heng, Xinlei, Qian, Chan, Conrad En Zuo, Sobota, Radoslaw, Kozma, Mary, Barcelli, Valeria, Wang, Guirong, Huang, Hairong, Floto, Andreas, Bifani, Pablo, Javid, Babak, MacAry, Paul A.
Publicado 2023

Author Correction: An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis

por Krishnananthasivam, Shivankari, Li, Hao, Bouzeyen, Rania, Shunmuganathan, Bhuvaneshwari, Purushotorman, Kiren, Liao, Xinlei, Du, Fengjiao, Friis, Claudia Guldager Kring, Crawshay-Williams, Felicity, Boon, Low Heng, Xinlei, Qian, Chan, Conrad En Zuo, Sobota, Radoslaw, Kozma, Mary, Barcelli, Valeria, Wang, Guirong, Huang, Hairong, Floto, Andreas, Bifani, Pablo, Javid, Babak, MacAry, Paul A.
Publicado 2023

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

por Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Publicado 2019

The IDentif.AI-x pandemic readiness platform: Rapid prioritization of optimized COVID-19 combination therapy regimens

por Blasiak, Agata, Truong, Anh T. L., Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond T. P., Lye, David C. B., Wong, John Eu-Li, Tan, Gek-Yen Gladys, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean
Publicado 2022