Protocol to use RNaseH1-based CRISPR to modulate locus-associated R-loops

por Khosraviani, Negin, Abraham, Karan J., Chan, Janet N.Y., Mekhail, Karim
Publicado 2022

RNA-cDNA hybrids mediate transposition via different mechanisms

por Todd, Lauren A., Hall, Amanda C., Pietrobon, Violena, Chan, Janet N. Y., Laflamme, Guillaume, Mekhail, Karim
Publicado 2020

Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair

por Oshidari, Roxanne, Strecker, Jonathan, Chung, Daniel K. C., Abraham, Karan J., Chan, Janet N. Y., Damaren, Christopher J., Mekhail, Karim
Publicado 2018

Intersection of calorie restriction and magnesium in the suppression of genome-destabilizing RNA–DNA hybrids

por Abraham, Karan J., Chan, Janet N.Y., Salvi, Jayesh S., Ho, Brandon, Hall, Amanda, Vidya, Elva, Guo, Ru, Killackey, Samuel A., Liu, Nancy, Lee, Jeffrey E., Brown, Grant W., Mekhail, Karim
Publicado 2016

Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats

por Ostrowski, Lauren A., Hall, Amanda C., Szafranski, Kirk J., Oshidari, Roxanne, Abraham, Karan J., Chan, Janet N. Y., Krustev, Christian, Zhang, Kevin, Wang, Ashley, Liu, Yupeng, Guo, Ru, Mekhail, Karim
Publicado 2018

Nucleolar RNA polymerase II drives ribosome biogenesis

por Abraham, Karan J., Khosraviani, Negin, Chan, Janet N.Y., Gorthi, Aparna, Samman, Anas, Zhao, Dorothy Y., Wang, Miling, Bokros, Michael, Vidya, Elva, Ostrowski, Lauren A., Oshidari, Roxanne, Pietrobon, Violena, Patel, Parasvi, Algouneh, Arash, Singhania, Rajat, Liu, Yupeng, Yerlici, V. Talya, De Carvalho, Daniel D., Ohh, Michael, Dickson, Brendan C., Hakem, Razq, Greenblatt, Jack F., Lee, Stephen, Bishop, Alexander J. R., Mekhail, Karim
Publicado 2020