Identification and Characterization of Mechanism of Action of P61-E7, a Novel Phosphine Catalysis-Based Inhibitor of Geranylgeranyltransferase-I

por Chan, Lai N., Fiji, Hannah D. G., Watanabe, Masaru, Kwon, Ohyun, Tamanoi, Fuyuhiko
Publicado 2011

In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells

por Zimonjic, Drazen B, Chan, Lai N, Tripathi, Veenu, Lu, Jie, Kwon, Ohyun, Popescu, Nicholas C, Lowy, Douglas R, Tamanoi, Fuyuhiko
Publicado 2013

Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia

por Hurtz, Christian, Chan, Lai N., Geng, Huimin, Ballabio, Erica, Xiao, Gang, Deb, Gauri, Khoury, Haytham, Chen, Chun-Wei, Armstrong, Scott A., Chen, Jianjun, Ernst, Patricia, Melnick, Ari, Milne, Thomas, Müschen, Markus
Publicado 2019

PTEN opposes negative selection and enables oncogenic transformation of pre-B cells

por Shojaee, Seyedmehdi, Chan, Lai N., Buchner, Maike, Cazzaniga, Valeria, Cosgun, Kadriye Nehir, Geng, Huimin, Qiu, Yi Hua, von Minden, Marcus Dühren, Ernst, Thomas, Hochhaus, Andreas, Cazzaniga, Giovanni, Melnick, Ari, Kornblau, Steven M., Graeber, Thomas G., Wu, Hong, Jumaa, Hassan, Müschen, Markus
Publicado 2016

Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses

por Contreras-Trujillo, Humberto, Eerdeng, Jiya, Akre, Samir, Jiang, Du, Contreras, Jorge, Gala, Basia, Vergel-Rodriguez, Mary C., Lee, Yeachan, Jorapur, Aparna, Andreasian, Areen, Harton, Lisa, Bramlett, Charles S., Nogalska, Anna, Xiao, Gang, Lee, Jae-Woong, Chan, Lai N., Müschen, Markus, Merchant, Akil A., Lu, Rong
Publicado 2021

Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

por Li, Mingli, Yang, Lu, Chan, Anthony K. N., Pokharel, Sheela Pangeni, Liu, Qiao, Mattson, Nicole, Xu, Xiaobao, Chang, Wen‐Han, Miyashita, Kazuya, Singh, Priyanka, Zhang, Leisi, Li, Maggie, Wu, Jun, Wang, Jinhui, Chen, Bryan, Chan, Lai N., Lee, Jaewoong, Zhang, Xu Hannah, Rosen, Steven T., Müschen, Markus, Qi, Jun, Chen, Jianjun, Hiom, Kevin, Bishop, Alexander J. R., Chen, Chun‐Wei
Publicado 2023

Metabolic gatekeeper function of B-lymphoid transcription factors

por Chan, Lai N., Chen, Zhengshan, Braas, Daniel, Lee, Jae-Woong, Xiao, Gang, Geng, Huimin, Cosgun, Kadriye Nehir, Hurtz, Christian, Shojaee, Seyedmehdi, Cazzaniga, Valeria, Schjerven, Hilde, Ernst, Thomas, Hochhaus, Andreas, Kornblau, Steven M., Konopleva, Marina, Pufall, Miles A., Cazzaniga, Giovanni, Liu, Grace J., Milne, Thomas A., Koeffler, H. Philip, Ross, Theodora S., Sanchez-Garcia, Isidro, Borkhardt, Arndt, Yamamoto, Keith R., Dickins, Ross A., Graeber, Thomas G., Müschen, Markus
Publicado 2017

Signaling input from divergent pathways subverts B-cell transformation

por Chan, Lai N., Murakami, Mark A., Robinson, Mark E., Caeser, Rebecca, Sadras, Teresa, Lee, Jaewoong, Cosgun, Kadriye Nehir, Kume, Kohei, Khairnar, Vishal, Xiao, Gang, Ahmed, Mohamed A., Aghania, Eamon, Deb, Gauri, Hurtz, Christian, Shojaee, Seyedmehdi, Hong, Chao, Pölönen, Petri, Nix, Matthew A., Chen, Zhengshan, Chen, Chun Wei, Chen, Jianjun, Vogt, Andreas, Heinäniemi, Merja, Lohi, Olli, Wiita, Arun P., Izraeli, Shai, Geng, Huimin, Weinstock, David M., Müschen, Markus
Publicado 2020

IFITM3 functions as PIP3-scaffold to amplify PI3K signaling in B-cells

por Lee, Jaewoong, Robinson, Mark E., Ma, Ning, Artadji, Dewan, Ahmed, Mohamed A., Xiao, Gang, Sadras, Teresa, Deb, Gauri, Winchester, Janet, Cosgun, Kadriye Nehir, Geng, Huimin, Chan, Lai N., Kume, Kohei, Miettinen, Teemu P., Zhang, Ye, Nix, Matthew A., Klemm, Lars, Chen, Chun Wei, Chen, Jianjun, Khairnar, Vishal, Wiita, Arun P., Thomas-Tikhonenko, Andrei, Farzan, Michael, Jung, Jae U., Weinstock, David M., Manalis, Scott R., Diamond, Michael S., Vaidehi, Nagarajan, Müschen, Markus
Publicado 2020