Quantitative MS‐Based Proteomics: Comparing the MCF‐7 Cellular Response to Hypoxia and a 2‐Oxoglutarate Analogue

por Bush, Jacob T., Chan, Mun Chiang, Mohammed, Shabaz, Schofield, Christopher J.
Publicado 2020

NUB1 and FAT10 Proteins as Potential Novel Biomarkers in Cancer: A Translational Perspective

por Arshad, Maria, Abdul Hamid, Nazefah, Chan, Mun Chiang, Ismail, Fuad, Tan, Geok Chin, Pezzella, Francesco, Tan, Ka-Liong
Publicado 2021

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

por Chan, Mun Chiang, Ilott, Nicholas E., Schödel, Johannes, Sims, David, Tumber, Anthony, Lippl, Kerstin, Mole, David R., Pugh, Christopher W., Ratcliffe, Peter J., Ponting, Chris P., Schofield, Christopher J.
Publicado 2016

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

por Tarhonskaya, Hanna, Rydzik, Anna M., Leung, Ivanhoe K. H., Loik, Nikita D., Chan, Mun Chiang, Kawamura, Akane, McCullagh, James S. O., Claridge, Timothy D. W., Flashman, Emily, Schofield, Christopher J.
Publicado 2014

A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1

por Schiller, Rachel, Scozzafava, Giuseppe, Tumber, Anthony, Wickens, James R, Bush, Jacob T, Rai, Ganesha, Lejeune, Clarisse, Choi, Hwanho, Yeh, Tzu-Lan, Chan, Mun Chiang, Mott, Bryan T, McCullagh, James S O, Maloney, David J, Schofield, Christopher J, Kawamura, Akane
Publicado 2014

An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability

por Schütte, Judith, Wang, Huange, Antoniou, Stella, Jarratt, Andrew, Wilson, Nicola K, Riepsaame, Joey, Calero-Nieto, Fernando J, Moignard, Victoria, Basilico, Silvia, Kinston, Sarah J, Hannah, Rebecca L, Chan, Mun Chiang, Nürnberg, Sylvia T, Ouwehand, Willem H, Bonzanni, Nicola, de Bruijn, Marella FTR, Göttgens, Berthold
Publicado 2016

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

por Chan, Mun Chiang, Atasoylu, Onur, Hodson, Emma, Tumber, Anthony, Leung, Ivanhoe K. H., Chowdhury, Rasheduzzaman, Gómez-Pérez, Verónica, Demetriades, Marina, Rydzik, Anna M., Holt-Martyn, James, Tian, Ya-Min, Bishop, Tammie, Claridge, Timothy D. W., Kawamura, Akane, Pugh, Christopher W., Ratcliffe, Peter J., Schofield, Christopher J.
Publicado 2015