Long term but not short term exposure to obesity related microbiota promotes host insulin resistance

por Foley, Kevin P., Zlitni, Soumaya, Denou, Emmanuel, Duggan, Brittany M., Chan, Rebecca W., Stearns, Jennifer C., Schertzer, Jonathan D.
Publicado 2018

Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice

por Cavallari, Joseph F., Anhê, Fernando F., Foley, Kevin P., Denou, Emmanuel, Chan, Rebecca W., Bowdish, Dawn M. E., Schertzer, Jonathan D.
Publicado 2018

Early Time-Dependent Dynamic Changes of TBET and GATA3 mRNA Expressions in Patients with Acute Coronary Syndrome

por Rainer, Timothy H., Graham, Colin A., Chan, Rebecca W. Y., Chan, Cangel P. Y., Tan, Patrick C. F., Yip, Gabriel W. K., Yu, Cheuk-Man
Publicado 2013

The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB

por Han, Diana S.C., Ni, Meng, Chan, Rebecca W.Y., Chan, Vicken W.H., Lui, Kathy O., Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado 2020

Nuclease deficiencies alter plasma cell-free DNA methylation profiles

por Han, Diana S.C., Ni, Meng, Chan, Rebecca W.Y., Wong, Danny K.L., Hiraki, Linda T., Volpi, Stefano, Jiang, Peiyong, Lui, Kathy O., Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado 2021

Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA

por Serpas, Lee, Chan, Rebecca W. Y., Jiang, Peiyong, Ni, Meng, Sun, Kun, Rashidfarrokhi, Ali, Soni, Chetna, Sisirak, Vanja, Lee, Wing-Shan, Cheng, Suk Hang, Peng, Wenlei, Chan, K. C. Allen, Chiu, Rossa W. K., Reizis, Boris, Lo, Y. M. Dennis
Publicado 2019

Effects of nucleases on cell-free extrachromosomal circular DNA

por Sin, Sarah T.K., Deng, Jiaen, Ji, Lu, Yukawa, Masashi, Chan, Rebecca W.Y., Volpi, Stefano, Vaglio, Augusto, Fenaroli, Paride, Bocca, Paola, Cheng, Suk Hang, Wong, Danny K.L., Lui, Kathy O., Jiang, Peiyong, Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado 2022

High-resolution analysis for urinary DNA jagged ends

por Xie, Tingting, Wang, Guangya, Ding, Spencer C., Lee, Wing-Shan, Cheng, Suk Hang, Chan, Rebecca W. Y., Zhou, Ze, Ma, Mary-Jane L., Han, Diana S. C., Teoh, Jeremy Y. C., Lam, W. K. Jacky, Jiang, Peiyong, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis
Publicado 2022

Detection and characterization of jagged ends of double-stranded DNA in plasma

por Jiang, Peiyong, Xie, Tingting, Ding, Spencer C., Zhou, Ze, Cheng, Suk Hang, Chan, Rebecca W.Y., Lee, Wing-Shan, Peng, Wenlei, Wong, John, Wong, Vincent W.S., Chan, Henry L.Y., Chan, Stephen L., Poon, Liona C.Y., Leung, Tak Y., Chan, K.C. Allen, Chiu, Rossa W.K., Lo, Y.M. Dennis
Publicado 2020

Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models

por Chen, Meihui, Chan, Rebecca W. Y., Cheung, Peter P. H., Ni, Meng, Wong, Danny K. L., Zhou, Ze, Ma, Mary-Jane L., Huang, Liangbo, Xu, Xinzhou, Lee, Wing-Shan, Wang, Guangya, Lui, Kathy O., Lam, W. K. Jacky, Teoh, Jeremy Y. C., Ng, Chi-Fai, Jiang, Peiyong, Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Publicado 2022

Epigenetic analysis of cell-free DNA by fragmentomic profiling

por Zhou, Qing, Kang, Guannan, Jiang, Peiyong, Qiao, Rong, Lam, W. K. Jacky, Yu, Stephanie C. Y., Ma, Mary-Jane L., Ji, Lu, Cheng, Suk Hang, Gai, Wanxia, Peng, Wenlei, Shang, Huimin, Chan, Rebecca W. Y., Chan, Stephen L., Wong, Grace L. H., Hiraki, Linda T., Volpi, Stefano, Wong, Vincent W. S., Wong, John, Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis
Publicado 2022

Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction

por Chan, Rebecca W.Y., Serpas, Lee, Ni, Meng, Volpi, Stefano, Hiraki, Linda T., Tam, Lai-Shan, Rashidfarrokhi, Ali, Wong, Priscilla C.H., Tam, Lydia H.P., Wang, Yueyang, Jiang, Peiyong, Cheng, Alice S.H., Peng, Wenlei, Han, Diana S.C., Tse, Patty P.P., Lau, Pik Ki, Lee, Wing-Shan, Magnasco, Alberto, Buti, Elisa, Sisirak, Vanja, AlMutairi, Nora, Chan, K.C. Allen, Chiu, Rossa W.K., Reizis, Boris, Lo, Y.M. Dennis
Publicado 2020

Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs

por Zhou, Ze, Ma, Mary-Jane L., Chan, Rebecca W. Y., Lam, W. K. Jacky, Peng, Wenlei, Gai, Wanxia, Hu, Xi, Ding, Spencer C., Ji, Lu, Zhou, Qing, Cheung, Peter P. H., Yu, Stephanie C. Y., Teoh, Jeremy Y. C., Szeto, Cheuk-Chun, Wong, John, Wong, Vincent W. S., Wong, Grace L. H., Chan, Stephen L., Hui, Edwin P., Ma, Brigette B. Y., Chan, Anthony T. C., Chiu, Rossa W. K., Chan, K. C. Allen, Lo, Y. M. Dennis, Jiang, Peiyong
Publicado 2023