CDKN2A germline alterations and the relevance of genotype-phenotype associations in cancer predisposition

por Chan, Sock Hoai, Chiang, Jianbang, Ngeow, Joanne
Publicado 2021

COVID-19 vaccination uptake and safety profile among germline BRCA1 and BRCA2 pathogenic variant carriers in Singapore

por Zhang, Zewen, Ishak, Nur Diana Binte, Que, Frances Victoria Fajardo, Chua, Zi Yang, Chan, Sock Hoai, Chiang, Jianbang, Yie, Joanne Ngeow Yuen
Publicado 2023

Functional analysis of clinical BARD1 germline variants

por Toh, Ming Ren, Chong, Siao Ting, Chan, Sock Hoai, Low, Chen Ee, Ishak, Nur Diana Binte, Lim, Jing Quan, Courtney, Eliza, Ngeow, Joanne
Publicado 2019

Functional characterisation guides classification of novel BAP1 germline variants

por Hong, Jing Han, Chong, Siao Ting, Lee, Po-Hsien, Tan, Jing, Heng, Hong Lee, Ishak, Nur Diana Binte, Chan, Sock Hoai, Teh, Bin Tean, Ngeow, Joanne
Publicado 2020

Multiple neoplasia in a patient with Gitelman syndrome harboring germline monoallelic MUTYH mutation

por Chan, Jason Yongsheng, Toh, Ming Ren, Chong, Siao Ting, Ishak, Nur Diana Binte, Kolinjivadi, Arun Mouli, Chan, Sock Hoai, Lee, Elizabeth, Boot, Arnoud, Shao-Tzu, Li, Chew, Min-Hoe, Ngeow, Joanne
Publicado 2020

Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level

por Li, Longjie, Kolinjivadi, Arun Mouli, Ong, Kok Haur, Young, David M, Marini, Gabriel Pik Liang, Chan, Sock Hoai, Chong, Siao Ting, Chew, Ee Ling, Lu, Haoda, Gole, Laurent, Yu, Weimiao, Ngeow, Joanne
Publicado 2022

Germline Pathogenic Variants in Homologous Recombination and DNA Repair Genes in an Asian Cohort of Young-Onset Colorectal Cancer

por Toh, Ming Ren, Chiang, Jian Bang, Chong, Siao Ting, Chan, Sock Hoai, Ishak, Nur Diana Binte, Courtney, Eliza, Lee, Wei Hao, Syed Abdillah Al, Syed Muhammad Fahmy Bin, Carson Allen, John, Lim, Kiat Hon, Davila, Sonia, Tan, Patrick, Lim, Weng Khong, Tan, Iain Bee Huat, Ngeow, Joanne
Publicado 2018

Germline hemizygous deletion of CDKN2A–CDKN2B locus in a patient presenting with Li–Fraumeni syndrome

por Chan, Sock Hoai, Lim, Weng Khong, Michalski, Scott T, Lim, Jing Quan, Ishak, Nur Diana Binte, Met-Domestici, Marie, Young, Cedric Ng Chuan, Vikstrom, Karen, Esplin, Edward D, Fulbright, Jennifer, Ang, Mei Kim, Wee, Joseph, Sittampalam, Kesavan, Farid, Mohamad, Lincoln, Stephen E, Itahana, Koji, Abdullah, Syafiq, Teh, Bin Tean, Ngeow, Joanne
Publicado 2016

Family history assessment significantly enhances delivery of precision medicine in the genomics era

por Bylstra, Yasmin, Lim, Weng Khong, Kam, Sylvia, Tham, Koei Wan, Wu, R. Ryanne, Teo, Jing Xian, Davila, Sonia, Kuan, Jyn Ling, Chan, Sock Hoai, Bertin, Nicolas, Yang, Cheng Xi, Rozen, Steve, Teh, Bin Tean, Yeo, Khung Keong, Cook, Stuart Alexander, Jamuar, Saumya Shekhar, Ginsburg, Geoffrey S., Orlando, Lori A., Tan, Patrick
Publicado 2021

Correction to: Family history assessment significantly enhances delivery of precision medicine in the genomics era

por Bylstra, Yasmin, Lim, Weng Khong, Kam, Sylvia, Tham, Koei Wan, Wu, R. Ryanne, Teo, Jing Xian, Davila, Sonia, Kuan, Jyn Ling, Chan, Sock Hoai, Bertin, Nicolas, Yang, Cheng Xi, Rozen, Steve, Teh, Bin Tean, Yeo, Khung Keong, Cook, Stuart Alexander, Jamuar, Saumya Shekhar, Ginsburg, Geoffrey S., Orlando, Lori A., Tan, Patrick
Publicado 2021

Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas

por Chan, Sock Hoai, Lim, Weng Khong, Ishak, Nur Diana Binte, Li, Shao-Tzu, Goh, Wei Lin, Tan, Gek San, Lim, Kiat Hon, Teo, Melissa, Young, Cedric Ng Chuan, Malik, Simeen, Tan, Mann Hong, Teh, Jonathan Yi Hui, Chin, Francis Kuok Choon, Kesavan, Sittampalam, Selvarajan, Sathiyamoorthy, Tan, Patrick, Teh, Bin Tean, Soo, Khee Chee, Farid, Mohamad, Quek, Richard, Ngeow, Joanne
Publicado 2017

Clinical relevance of screening checklists for detecting cancer predisposition syndromes in Asian childhood tumours

por Chan, Sock Hoai, Chew, Winston, Ishak, Nur Diana Binte, Lim, Weng Khong, Li, Shao-Tzu, Tan, Sheng Hui, Teo, Jing Xian, Shaw, Tarryn, Chang, Kenneth, Chen, Yong, Iyer, Prasad, Tan, Enrica Ee Kar, Seng, Michaela Su-Fern, Chan, Mei Yoke, Tan, Ah Moy, Low, Sharon Yin Yee, Soh, Shui Yen, Loh, Amos Hong Pheng, Ngeow, Joanne
Publicado 2018

Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma

por Chng, Kern Rei, Chan, Sock Hoai, Ng, Amanda Hui Qi, Li, Chenhao, Jusakul, Apinya, Bertrand, Denis, Wilm, Andreas, Choo, Su Pin, Tan, Damien Meng Yew, Lim, Kiat Hon, Soetinko, Roy, Ong, Choon Kiat, Duda, Dan G., Dima, Simona, Popescu, Irinel, Wongkham, Chaisiri, Feng, Zhu, Yeoh, Khay Guan, Teh, Bin Tean, Yongvanit, Puangrat, Wongkham, Sopit, Bhudhisawasdi, Vajaraphongsa, Khuntikeo, Narong, Tan, Patrick, Pairojkul, Chawalit, Ngeow, Joanne, Nagarajan, Niranjan
Publicado 2016

Whole exome sequencing identifies recessive germline mutations in FAM160A1 in familial NK/T cell lymphoma

por Chan, Jason Yongsheng, Ng, Alvin Yu Jin, Cheng, Chee Leong, Nairismägi, Maarja-Liisa, Venkatesh, Byrappa, Cheah, Daryl Ming Zhe, Li, Shao-Tzu, Chan, Sock Hoai, Ngeow, Joanne, Laurensia, Yurike, Lim, Jing Quan, Pang, Jane Wan Lu, Nagarajan, Sanjanaa, Song, Tammy, Chia, Burton, Tan, Jing, Huang, Dachuan, Goh, Yeow Tee, Poon, Eileen, Somasundaram, Nagavalli, Tao, Miriam, Quek, Richard Hong Hui, Farid, Mohamad, Khor, Chiea Chuen, Bei, Jin-Xin, Tan, Soo Yong, Lim, Soon Thye, Ong, Choon Kiat, Tang, Tiffany
Publicado 2018

Analysis of clinically relevant variants from ancestrally diverse Asian genomes

por Chan, Sock Hoai, Bylstra, Yasmin, Teo, Jing Xian, Kuan, Jyn Ling, Bertin, Nicolas, Gonzalez-Porta, Mar, Hebrard, Maxime, Tirado-Magallanes, Roberto, Tan, Joanna Hui Juan, Jeyakani, Justin, Li, Zhihui, Chai, Jin Fang, Chong, Yap Seng, Davila, Sonia, Goh, Liuh Ling, Lee, Eng Sing, Wong, Eleanor, Wong, Tien Yin, Prabhakar, Shyam, Liu, Jianjun, Cheng, Ching-Yu, Eisenhaber, Birgit, Karnani, Neerja, Leong, Khai Pang, Sim, Xueling, Yeo, Khung Keong, Chambers, John C., Tai, E-Shyong, Tan, Patrick, Jamuar, Saumya S., Ngeow, Joanne, Lim, Weng Khong
Publicado 2022

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk

por Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K., Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J., Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S., Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D. Gareth R., Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B., González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N.A., Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L., Nevanlinna, Heli, Olson, Janet E., Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E., Rosseel, Toon, Ruddy, Kathryn J., Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E., Trentham-Dietz, Amy, Vachon, Celine M., Volk, Alexander E., Weber-Lassalle, Nana, Weitzel, Jeffrey N., Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B., Vega, Ana, Rossing, Maria, Del Valle, Jesús, De Nicolo, Arcangela, Hahnen, Eric, Claes, Kathleen B.M., Ngeow, Joanne, Momozawa, Yukihide, James, Paul A., Couch, Fergus J., Macurek, Libor, Kleibl, Zdenek
Publicado 2023