Experimental and Therapeutic Opportunities for Stem Cells in Multiple Sclerosis

por Patani, Rickie, Chandran, Siddharthan
Publicado 2012

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration

por Gupta, Kunal, Chandran, Siddharthan, Hardingham, Giles E
Publicado 2013

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons

por Gupta, Kunal, Hardingham, Giles E., Chandran, Siddharthan
Publicado 2013

Patterns of Cognitive Dysfunction in Progressive MS

por Connick, Peter, Chandran, Siddharthan, Bak, Thomas H.
Publicado 2013

Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells

por Selvaraj, Bhuvaneish T., Livesey, Matthew R., Chandran, Siddharthan
Publicado 2017

Human Stem Cell-Derived Neurons: A System to Study Human Tau Function and Dysfunction

por Iovino, Mariangela, Patani, Rickie, Watts, Colin, Chandran, Siddharthan, Spillantini, Maria Grazia
Publicado 2010

Unpicking neurodegeneration in a dish with human pluripotent stem cells: One cell type at a time

por Bilican, Bilada, Serio, Andrea, Shaw, Christopher E, Maniatis, Tom, Chandran, Siddharthan
Publicado 2013

Could an Impairment in Local Translation of mRNAs in Glia be Contributing to Pathogenesis in ALS?

por Barton, Samantha K., Gregory, Jenna M., Chandran, Siddharthan, Turner, Bradley J.
Publicado 2019

Induction of Olig2(+) Precursors by FGF Involves BMP Signalling Blockade at the Smad Level

por Bilican, Bilada, Fiore-Heriche, Christelle, Compston, Alastair, Allen, Nicholas D., Chandran, Siddharthan
Publicado 2008

Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming

por Rzechorzek, Nina Marie, Connick, Peter, Patani, Rickie, Selvaraj, Bhuvaneish Thangaraj, Chandran, Siddharthan
Publicado 2015

Defining novel functions for cerebrospinal fluid in ALS pathophysiology

por Ng Kee Kwong, Koy Chong, Mehta, Arpan R., Nedergaard, Maiken, Chandran, Siddharthan
Publicado 2020

Blood-CNS barrier dysfunction in amyotrophic lateral sclerosis: Proposed mechanisms and clinical implications

por Steinruecke, Moritz, Lonergan, Rebecca Murphy, Selvaraj, Bhuvaneish T, Chandran, Siddharthan, Diaz-Castro, Blanca, Stavrou, Maria
Publicado 2023

Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells

por Livesey, Matthew R., Magnani, Dario, Hardingham, Giles E., Chandran, Siddharthan, Wyllie, David J. A.
Publicado 2015

The clinico-radiological paradox of cognitive function and MRI burden of white matter lesions in people with multiple sclerosis: A systematic review and meta-analysis

por Mollison, Daisy, Sellar, Robin, Bastin, Mark, Mollison, Denis, Chandran, Siddharthan, Wardlaw, Joanna, Connick, Peter
Publicado 2017

Multi-modal retinal scanning to measure retinal thickness and peripheral blood vessels in multiple sclerosis

por Pearson, Thomas, Chen, Yingdi, Dhillon, Baljean, Chandran, Siddharthan, van Hemert, Jano, MacGillivray, Tom
Publicado 2022

The Patient Health Questionnaire (PHQ-9) as a tool to screen for depression in people with multiple sclerosis: a cross-sectional validation study

por Beswick, Emily, Quigley, Suzanne, Macdonald, Pamela, Patrick, Sarah, Colville, Shuna, Chandran, Siddharthan, Connick, Peter
Publicado 2022

Renewed assessment of the risk of emergent advanced cell therapies to transmit neuroproteinopathies

por De Sousa, Paul A., Ritchie, Diane, Green, Alison, Chandran, Siddharthan, Knight, Richard, Head, Mark W.
Publicado 2018

Neuronal Activity and Its Role in Controlling Antioxidant Genes

por Qiu, Jing, Dando, Owen, Febery, James A., Fowler, Jill H., Chandran, Siddharthan, Hardingham, Giles E.
Publicado 2020

Therapeutic Targeting of Proteostasis in Amyotrophic Lateral Sclerosis—a Systematic Review and Meta-Analysis of Preclinical Research

por Elliott, Elizabeth, Bailey, Olivia, Waldron, Fergal M., Hardingham, Giles E., Chandran, Siddharthan, Gregory, Jenna M.
Publicado 2020

Cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis: a systematic review of in vitro studies

por Ng Kee Kwong, Koy Chong, Gregory, Jenna M, Pal, Suvankar, Chandran, Siddharthan, Mehta, Arpan R
Publicado 2020