Induction and Monitoring of Adoptive Delayed-Type Hypersensitivity in Rats

por Beeton, Christine, Chandy, K. George
Publicado 2007

Structure of the voltage-gated potassium channel K(V)1.3: Insights into the inactivated conformation and binding to therapeutic leads

por Chandy, K. George, Sanches, Karoline, Norton, Raymond S.
Publicado 2023

A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue

por Hou, Aihua, Bose, Tanima, Chandy, K. George, Tong, Louis
Publicado 2017

Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels

por Ong, Seow Theng, Tyagi, Anu, Chandy, K. George, Bhushan, Shashi
Publicado 2022

Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease

por Bose, Tanima, Lee, Ryan, Hou, Aihua, Tong, Louis, Chandy, K. George
Publicado 2017

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

por Bose, Tanima, Hou, Aihua, Lee, Ryan, Tong, Louis, Chandy, K. George
Publicado 2017

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

por Leanza, Luigi, Henry, Brian, Sassi, Nicola, Zoratti, Mario, Chandy, K George, Gulbins, Erich, Szabò, Ildikò
Publicado 2012

Structures of wild-type and H451N mutant human lymphocyte potassium channel K(V)1.3

por Liu, Sanling, Zhao, Yue, Dong, Hao, Xiao, Liang, Zhang, Yong, Yang, Yuqin, Ong, Seow Theng, Chandy, K. George, Zhang, Longhua, Tian, Changlin
Publicado 2021

Kv1.3 Channel Up-Regulation in Peripheral Blood T Lymphocytes of Patients With Multiple Sclerosis

por Markakis, Ioannis, Charitakis, Ioannis, Beeton, Christine, Galani, Melpomeni, Repousi, Elpida, Aggeloglou, Stella, Sfikakis, Petros P., Pennington, Michael W., Chandy, K. George, Poulopoulou, Cornelia
Publicado 2021

Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug

por Tyagi, Anu, Ahmed, Tofayel, Jian, Shi, Bajaj, Saumya, Ong, Seow Theng, Goay, Stephanie Shee Min, Zhao, Yue, Vorobyov, Igor, Tian, Changlin, Chandy, K. George, Bhushan, Shashi
Publicado 2022

Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint

por Verma, Navin Kumar, Wong, Brandon Han Siang, Poh, Zhi Sheng, Udayakumar, Aiswarya, Verma, Ritu, Goh, Ryan Kwang Jin, Duggan, Shane P., Shelat, Vishalkumar G., Chandy, K. George, Grigoropoulos, Nicholas Francis
Publicado 2022

The combined activation of K(Ca)3.1 and inhibition of K(v)11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells

por Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, K George, Becchetti, Andrea, Arcangeli, Annarosa
Publicado 2018

Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response

por Goggi, Julian L., Khanapur, Shivashankar, Ramasamy, Boominathan, Hartimath, Siddesh V., Rong, Tang Jun, Cheng, Peter, Tan, Yun Xuan, Yeo, Xin Yi, Jung, Sangyong, Goay, Stephanie Shee Min, Ong, Seow Theng, Hwang, You Yi, Chandy, K. George, Robins, Edward G.
Publicado 2022

Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis

por Mkhikian, Haik, Grigorian, Ani, Li, Carey F., Chen, Hung-Lin, Newton, Barbara, Zhou, Raymond W., Beeton, Christine, Torossian, Sevan, Tatarian, Gevork Grikor, Lee, Sung-Uk, Lau, Ken, Walker, Erin, Siminovitch, Katherine A., Chandy, K. George, Yu, Zhaoxia, Dennis, James W., Demetriou, Michael
Publicado 2011

CD4(+) T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice

por Her, Zhisheng, Tan, Joel Heng Loong, Lim, Yee-Siang, Tan, Sue Yee, Chan, Xue Ying, Tan, Wilson Wei Sheng, Liu, Min, Yong, Kylie Su Mei, Lai, Fritz, Ceccarello, Erica, Zheng, Zhiqiang, Fan, Yong, Chang, Kenneth Tou En, Sun, Lei, Chang, Shih Chieh, Chin, Chih-Liang, Lee, Guan Huei, Dan, Yock Young, Chan, Yun-Shen, Lim, Seng Gee, Chan, Jerry Kok Yen, Chandy, K. George, Chen, Qingfeng
Publicado 2020