Evolution and Origin of HRS, a Protein Interacting with Merlin, the Neurofibromatosis 2 Gene Product

por Omelyanchuk, Leonid V., Pertseva, Julia A., Burns, Sarah S., Chang, Long-Sheng
Publicado 2009

Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene

por Golovnina, Kseniya, Blinov, Alexander, Akhmametyeva, Elena M, Omelyanchuk, Leonid V, Chang, Long-Sheng
Publicado 2005

Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

por Amaravathi, Anusha, Oblinger, Janet L., Welling, D. Bradley, Kinghorn, A. Douglas, Chang, Long-Sheng
Publicado 2021

LIM Domain Kinases as Potential Therapeutic Targets for Neurofibromatosis Type 2

por Petrilli, Alejandra, Copik, Alicja, Posadas, Michelle, Chang, Long-Sheng, Welling, D. Bradley, Giovannini, Marco, Fernández-Valle, Cristina
Publicado 2013

The role of Drosophila Merlin in spermatogenesis

por Dorogova, Natalia V, Akhmametyeva, Elena M, Kopyl, Sergei A, Gubanova, Natalia V, Yudina, Olga S, Omelyanchuk, Leonid V, Chang, Long-Sheng
Publicado 2008

Group I Paks as therapeutic targets in NF2-deficient meningioma

por Chow, Hoi-Yee, Dong, Biao, Duron, Sergio G., Campbell, David A., Ong, Christy C., Hoeflich, Klaus P., Chang, Long-Sheng, Welling, D. Bradley, Yang, Zeng-jie, Chernoff, Jonathan
Publicado 2015

Ponatinib promotes a G(1) cell-cycle arrest of merlin/NF2-deficient human schwann cells

por Petrilli, Alejandra M, Garcia, Jeanine, Bott, Marga, Plati, Stephani Klingeman, Dinh, Christine T, Bracho, Olena R, Yan, Denise, Zou, Bing, Mittal, Rahul, Telischi, Fred F, Liu, Xue-Zhong, Chang, Long-Sheng, Bradley, D Welling, Copik, Alicja J, Fernández-Valle, Cristina
Publicado 2017

Early phase clinical studies of AR‐42, a histone deacetylase inhibitor, for neurofibromatosis type 2‐associated vestibular schwannomas and meningiomas

por Welling, D. Bradley, Collier, Katharine A., Burns, Sarah S., Oblinger, Janet L., Shu, Edina, Miles‐Markley, Beth A., Hofmeister, Craig C., Makary, Mina S., Slone, H. Wayne, Blakeley, Jaishri O., Mansouri, S. Alireza, Neff, Brian A., Jackler, Robert K., Mortazavi, Amir, Chang, Long‐Sheng
Publicado 2021

Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy

por Wu, Lai Man Natalie, Zhang, Feng, Rao, Rohit, Adam, Mike, Pollard, Kai, Szabo, Sara, Liu, Xuezhao, Belcher, Katie A., Luo, Zaili, Ogurek, Sean, Reilly, Colleen, Zhou, Xin, Zhang, Li, Rubin, Joshua, Chang, Long-sheng, Xin, Mei, Yu, Jiyang, Suva, Mario, Pratilas, Christine A., Potter, Steven, Lu, Q. Richard
Publicado 2022

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

por Allaway, Robert, Angus, Steve P., Beauchamp, Roberta L., Blakeley, Jaishri O., Bott, Marga, Burns, Sarah S., Carlstedt, Annemarie, Chang, Long-Sheng, Chen, Xin, Clapp, D. Wade, Desouza, Patrick A., Erdin, Serkan, Fernandez-Valle, Cristina, Guinney, Justin, Gusella, James F., Haggarty, Stephen J., Johnson, Gary L., La Rosa, Salvatore, Morrison, Helen, Petrilli, Alejandra M., Plotkin, Scott R., Pratap, Abhishek, Ramesh, Vijaya, Sciaky, Noah, Stemmer-Rachamimov, Anat, Stuhlmiller, Tim J., Talkowski, Michael E., Welling, D. Bradley, Yates, Charles W., Zawistowski, Jon S., Zhao, Wen-Ning
Publicado 2018

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

por Chang, Long-Sheng, Oblinger, Janet L., Smith, Abbi E., Ferrer, Marc, Angus, Steven P., Hawley, Eric, Petrilli, Alejandra M., Beauchamp, Roberta L., Riecken, Lars Björn, Erdin, Serkan, Poi, Ming, Huang, Jie, Bessler, Waylan K., Zhang, Xiaohu, Guha, Rajarshi, Thomas, Craig, Burns, Sarah S., Gilbert, Thomas S. K., Jiang, Li, Li, Xiaohong, Lu, Qingbo, Yuan, Jin, He, Yongzheng, Dixon, Shelley A. H., Masters, Andrea, Jones, David R., Yates, Charles W., Haggarty, Stephen J., La Rosa, Salvatore, Welling, D. Bradley, Stemmer-Rachamimov, Anat O., Plotkin, Scott R., Gusella, James F., Guinney, Justin, Morrison, Helen, Ramesh, Vijaya, Fernandez-Valle, Cristina, Johnson, Gary L., Blakeley, Jaishri O., Clapp, D. Wade
Publicado 2021