Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces

por Lee, Myungjin, Changela, Anita, Gorman, Jason, Rawi, Reda, Bylund, Tatsiana, Chao, Cara W., Lin, Bob C., Louder, Mark K., Olia, Adam S., Zhang, Baoshan, Doria-Rose, Nicole A., Zolla-Pazner, Susan, Shapiro, Lawrence, Chuang, Gwo-Yu, Kwong, Peter D.
Publicado 2021

A Platform Incorporating Trimeric Antigens into Self-Assembling Nanoparticles Reveals SARS-CoV-2-Spike Nanoparticles to Elicit Substantially Higher Neutralizing Responses than Spik...

por Zhang, Baoshan, Chao, Cara W., Tsybovsky, Yaroslav, Abiona, Olubukola M., Hutchinson, Geoffrey B., Moliva, Juan I., Olia, Adam S., Pegu, Amarendra, Phung, Emily, Stewart-Jones, Guillaume, Verardi, Raffaello, Wang, Lingshu, Wang, Shuishu, Werner, Anne, Yang, Eun Sung, Yap, Christina, Zhou, Tongqing, Mascola, John R., Sullivan, Nancy J., Graham, Barney S., Corbett, Kizzmekia S., Kwong, Peter D.
Publicado 2020

A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than spik...

por Zhang, Baoshan, Chao, Cara W., Tsybovsky, Yaroslav, Abiona, Olubukola M., Hutchinson, Geoffrey B., Moliva, Juan I., Olia, Adam S., Pegu, Amarendra, Phung, Emily, Stewart-Jones, Guillaume B. E., Verardi, Raffaello, Wang, Lingshu, Wang, Shuishu, Werner, Anne, Yang, Eun Sung, Yap, Christina, Zhou, Tongqing, Mascola, John R., Sullivan, Nancy J., Graham, Barney S., Corbett, Kizzmekia S., Kwong, Peter D.
Publicado 2020

Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency

por Zhang, Baoshan, Gorman, Jason, Kwon, Young D., Pegu, Amarendra, Chao, Cara W., Liu, Tracy, Asokan, Mangaiarkarasi, Bender, Michael F., Bylund, Tatsiana, Damron, Leland, Gollapudi, Deepika, Lei, Paula, Li, Yile, Liu, Cuiping, Louder, Mark K., McKee, Krisha, Olia, Adam S., Rawi, Reda, Schön, Arne, Wang, Shuishu, Yang, Eun Sung, Yang, Yongping, Carlton, Kevin, Doria-Rose, Nicole A., Shapiro, Lawrence, Seaman, Michael S., Mascola, John R., Kwong, Peter D.
Publicado 2023

Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life

por Zhang, Baoshan, Gollapudi, Deepika, Gorman, Jason, O’Dell, Sijy, Damron, Leland F., McKee, Krisha, Asokan, Mangaiarkarasi, Yang, Eun Sung, Pegu, Amarendra, Lin, Bob C., Chao, Cara W., Chen, Xuejun, Gama, Lucio, Ivleva, Vera B., Law, William H., Liu, Cuiping, Louder, Mark K., Schmidt, Stephen D., Shen, Chen-Hsiang, Shi, Wei, Stein, Judith A., Seaman, Michael S., McDermott, Adrian B., Carlton, Kevin, Mascola, John R., Kwong, Peter D., Lei, Q. Paula, Doria-Rose, Nicole A.
Publicado 2022

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

por Ou, Li, Kong, Wing-Pui, Chuang, Gwo-Yu, Ghosh, Mridul, Gulla, Krishana, O’Dell, Sijy, Varriale, Joseph, Barefoot, Nathan, Changela, Anita, Chao, Cara W., Cheng, Cheng, Druz, Aliaksandr, Kong, Rui, McKee, Krisha, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Shaddeau, Andrew, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Wanninger, Timothy G., Xu, Kai, Yang, Gengcheng J., Zhang, Baoshan, Zhang, Yaqiu, Zhou, Tongqing, Arnold, Frank J., Doria-Rose, Nicole A., Lei, Q. Paula, Ryan, Edward T., Vann, Willie F., Mascola, John R., Kwong, Peter D.
Publicado 2020