Functional Characterization of N297A, A Murine Surrogate for low-Fc Binding Anti-Human CD3 Antibodies

por Chao, Debra T., Ma, Xiaohong, Li, Olga, Park, Hyunjoo, Law, Debbie
Publicado 2009

Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-α pathways

por Balasa, Balaji, Yun, Rui, Belmar, Nicole A., Fox, Melvin, Chao, Debra T., Robbins, Michael D., Starling, Gary C., Rice, Audie G.
Publicado 2014

A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth in vivo

por Bhaskar, Vinay, Zhang, Dong, Fox, Melvin, Seto, Pui, Wong, Melanie HL, Wales, Pauline E, Powers, David, Chao, Debra T, DuBridge, Robert B, Ramakrishnan, Vanitha
Publicado 2007

Enavatuzumab, a Humanized Anti-TWEAK Receptor Monoclonal Antibody, Exerts Antitumor Activity through Attracting and Activating Innate Immune Effector Cells

por Ye, Shiming, Fox, Melvin I., Belmar, Nicole A., Sho, Mien, Chao, Debra T., Choi, Donghee, Fang, Yuni, Zhao, Vivian, Keller, Stephen F., Starling, Gary C., Culp, Patricia A.
Publicado 2017

Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR

por Purcell, James W., Kim, Han K., Tanlimco, Sonia G., Doan, Minhtam, Fox, Melvin, Lambert, Peter, Chao, Debra T., Sho, Mien, Wilson, Keith E., Starling, Gary C., Culp, Patricia A.
Publicado 2014

Expression of TweakR in breast cancer and preclinical activity of enavatuzumab, a humanized anti-TweakR mAb

por Chao, Debra T., Su, Mian, Tanlimco, Sonia, Sho, Mien, Choi, Donghee, Fox, Mel, Ye, Shiming, Hsi, Eric D., Durkin, Lisa, Yin, Johnny, Zhang, Yongke, Kim, Han, Starling, Gary C., Culp, Patricia A.
Publicado 2012

PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis

por Woo, Jacky, Vierboom, Michel PM, Kwon, Hakju, Chao, Debra, Ye, Shiming, Li, Jianmin, Lin, Karen, Tang, Irene, Belmar, Nicole A, Hartman, Taymar, Breedveld, Elia, Vexler, Vladimir, ‘t Hart, Bert A, Law, Debbie A, Starling, Gary C
Publicado 2013

VISTA is an activating receptor in human monocytes

por Rogers, Bryan M., Smith, Laura, Dezso, Zoltan, Shi, Xu, DiGiammarino, Enrico, Nguyen, Denny, Sethuraman, Sunantha, Zheng, Pingping, Choi, Donghee, Zhang, Dong, Nguyen, Andrew, McGuire, Kathleen, Liu, Wei, Chung, Namjin, Chao, Debra T., Ye, Shiming, Starbeck-Miller, Gabriel R.
Publicado 2021

Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors

por Luke, Jason J, Barlesi, Fabrice, Chung, Ki, Tolcher, Anthony W, Kelly, Karen, Hollebecque, Antoine, Le Tourneau, Christophe, Subbiah, Vivek, Tsai, Frank, Kao, Steven, Cassier, Philippe A, Khasraw, Mustafa, Kindler, Hedy L, Fang, Hua, Fan, Frances, Allaire, Kathryn, Patel, Maulik, Ye, Shiming, Chao, Debra T, Henner, William R, Hayflick, Joel S, McDevitt, Michael A, Fong, Lawrence
Publicado 2021