A cylindrical assembly model and dynamics of the Ebola virus VP40 structural matrix

por Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Publicado 2018

Investigating molecular interactions between oxidized neuroglobin and cytochrome c

por Tiwari, Purushottam B., Chapagain, Prem P., Üren, Aykut
Publicado 2018

Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays

por Sandhaus, Shayna, Chapagain, Prem P., Tse-Dinh, Yuk-Ching
Publicado 2018

In-silico identification of the vaccine candidate epitopes against the Lassa virus hemorrhagic fever

por Baral, Prabin, Pavadai, Elumalai, Gerstman, Bernard S., Chapagain, Prem P.
Publicado 2020

Plasma membrane association facilitates conformational changes in the Marburg virus protein VP40 dimer

por Bhattarai, Nisha, GC, Jeevan B., Gerstman, Bernard S., Stahelin, Robert V., Chapagain, Prem P.
Publicado 2017

AT-hook peptides bind the major and minor groove of AT-rich DNA duplexes

por Garabedian, Alyssa, Jeanne Dit Fouque, Kevin, Chapagain, Prem P, Leng, Fenfei, Fernandez-Lima, Francisco
Publicado 2022

A Conserved Tryptophan in the Ebola Virus Matrix Protein C-Terminal Domain Is Required for Efficient Virus-Like Particle Formation

por Johnson, Kristen A., Pokhrel, Rudramani, Budicini, Melissa R., Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Publicado 2020

Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B.1.617.2 and implications for immune evasion

por Baral, Prabin, Bhattarai, Nisha, Hossen, Md Lokman, Stebliankin, Vitalii, Gerstman, Bernard S., Narasimhan, Giri, Chapagain, Prem P.
Publicado 2021

Changes in the receptor-binding interface may cause immune evasion by the SARS-CoV-2 delta variant b.1.617.2

por Baral, Prabin, Bhattarai, Nisha, Lokman Hossen, Md, Stebliankin, Vitalii, Gerstman, Bernard S., Narasimhan, Giri, Chapagain, Prem P.
Publicado 2022

Detection of lipid-induced structural changes of the Marburg virus matrix protein VP40 using hydrogen/deuterium exchange-mass spectrometry

por Wijesinghe, Kaveesha J., Urata, Sarah, Bhattarai, Nisha, Kooijman, Edgar E., Gerstman, Bernard S., Chapagain, Prem P., Li, Sheng, Stahelin, Robert V.
Publicado 2017

Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

por Wijesinghe, Kaveesha J., McVeigh, Luke, Husby, Monica L., Bhattarai, Nisha, Ma, Jia, Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Publicado 2020

The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection

por Beddingfield, Brandon J., Iwanaga, Naoki, Chapagain, Prem P., Zheng, Wenshu, Roy, Chad J., Hu, Tony Y., Kolls, Jay K., Bix, Gregory J.
Publicado 2020

Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly

por Amiar, Souad, Husby, Monica L., Wijesinghe, Kaveesha J., Angel, Stephanie, Bhattarai, Nisha, Gerstman, Bernard S., Chapagain, Prem P., Li, Sheng, Stahelin, Robert V.
Publicado 2021

Cysteine Mutations in the Ebolavirus Matrix Protein VP40 Promote Phosphatidylserine Binding by Increasing the Flexibility of a Lipid-Binding Loop

por Johnson, Kristen A., Bhattarai, Nisha, Budicini, Melissa R., LaBonia, Carolyn M., Baker, Sarah Catherine B., Gerstman, Bernard S., Chapagain, Prem P., Stahelin, Robert V.
Publicado 2021

Identification of HMGA2 inhibitors by AlphaScreen-based ultra-high-throughput screening assays

por Su, Linjia, Bryan, Nadezda, Battista, Sabrina, Freitas, Juliano, Garabedian, Alyssa, D’Alessio, Federica, Romano, Miriam, Falanga, Fabiana, Fusco, Alfredo, Kos, Lidia, Chambers, Jeremy, Fernandez-Lima, Francisco, Chapagain, Prem P., Vasile, Stefan, Smith, Layton, Leng, Fenfei
Publicado 2020

Measles and Nipah virus assembly: Specific lipid binding drives matrix polymerization

por Norris, Michael J., Husby, Monica L., Kiosses, William B., Yin, Jieyun, Saxena, Roopashi, Rennick, Linda J., Heiner, Anja, Harkins, Stephanie S., Pokhrel, Rudramani, Schendel, Sharon L., Hastie, Kathryn M., Landeras-Bueno, Sara, Salie, Zhe Li, Lee, Benhur, Chapagain, Prem P., Maisner, Andrea, Duprex, W. Paul, Stahelin, Robert V., Saphire, Erica Ollmann
Publicado 2022