eIF4A inhibition: ready for primetime?

por Cunningham, Tyler A., Chapman, Eli, Schatz, Jonathan H.
Publicado 2018

NRF2 negatively regulates primary ciliogenesis and hedgehog signaling

por Liu, Pengfei, Dodson, Matthew, Fang, Deyu, Chapman, Eli, Zhang, Donna D.
Publicado 2020

Inhibitors of the AAA+ Chaperone p97

por Chapman, Eli, Maksim, Nick, de la Cruz, Fabian, La Clair, James J.
Publicado 2015

Correction: Chapman, E.; et al. Inhibitors of the AAA+ Chaperone p97. Molecules 2015, 20, 3027-3049

por Chapman, Eli, Maksim, Nick, de la Cruz, Fabian, La Clair, James J.
Publicado 2015

Anti-Ferroptotic Effects of Nrf2: Beyond the Antioxidant Response

por Shakya, Aryatara, McKee, Nicholas W., Dodson, Matthew, Chapman, Eli, Zhang, Donna D.
Publicado 2023

In Situ Natural Product Discovery via an Artificial Marine Sponge

por La Clair, James J., Loveridge, Steven T., Tenney, Karen, O'Neil–Johnson, Mark, Chapman, Eli, Crews, Phillip
Publicado 2014

Molecular Dynamics Simulations Identify Tractable Lead-like Phenyl-Piperazine Scaffolds as eIF4A1 ATP-competitive Inhibitors

por Essegian, Derek J., Cunningham, Tyler A., Zerio, Christopher J., Chapman, Eli, Schatz, Jonathan, Schürer, Stephan C.
Publicado 2021

Subcellular Protein Localization by Using a Genetically Encoded Fluorescent Amino Acid

por Charbon, Godefroid, Brustad, Eric, Scott, Kevin A, Wang, Jiangyun, Løbner-Olesen, Anders, Schultz, Peter G, Jacobs-Wagner, Christine, Chapman, Eli
Publicado 2011

Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention

por Harder, Bryan, Jiang, Tao, Wu, Tongde, Tao, Shasha, de la Vega, Montserrat Rojo, Tian, Wang, Chapman, Eli, Zhang, Donna D.
Publicado 2015

Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis

por Wu, Tongde, Zhao, Fei, Gao, Beixue, Tan, Can, Yagishita, Naoko, Nakajima, Toshihiro, Wong, Pak K., Chapman, Eli, Fang, Deyu, Zhang, Donna D.
Publicado 2014

Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease

por Liu, Pengfei, Anandhan, Annadurai, Chen, Jinjing, Shakya, Aryatara, Dodson, Matthew, Ooi, Aikseng, Chapman, Eli, White, Eileen, Garcia, Joe GN., Zhang, Donna D.
Publicado 2022

The NRF2-LOC344887 signaling axis suppresses pulmonary fibrosis

por Liu, Pengfei, Luo, Gang, Dodson, Matthew, Schmidlin, Cody J., Wei, Yongyi, Kerimoglu, Baris, Ooi, Aikseng, Chapman, Eli, Garcia, Joe GN., Zhang, Donna D.
Publicado 2020

The NRF2-p97-NRF2 negative feedback loop

por Shakya, Aryatara, Liu, Pengfei, Godek, Jack, McKee, Nicholas W., Dodson, Matthew, Anandhan, Annadurai, Ooi, Aikseng, Garcia, Joe G.N., Costa, Max, Chapman, Eli, Zhang, Donna D.
Publicado 2023

CHML is an NRF2 target gene that regulates mTOR function

por Dodson, Matthew, Dai, Wujing, Anandhan, Annadurai, Schmidlin, Cody J., Liu, Pengfei, Wilson, Nathan C., Wei, Yongyi, Kitamura, Naoya, Galligan, James J., Ooi, Aikseng, Chapman, Eli, Zhang, Donna D.
Publicado 2022

A two-step resin based approach to reveal survivin-selective fluorescent probes

por Ambrose, Andrew J., Pham, Nhan T., Sivinski, Jared, Guimarães, Larissa, Mollasalehi, Niloufar, Jimenez, Paula, Abad, Maria A., Jeyaprakash, A. Arockia, Shave, Steven, Costa-Lotufo, Letícia V., La Clair, James J., Auer, Manfred, Chapman, Eli
Publicado 2020

Non-canonical NRF2 activation promotes a pro-diabetic shift in hepatic glucose metabolism

por Liu, Pengfei, Dodson, Matthew, Li, Hui, Schmidlin, Cody J., Shakya, Aryatara, Wei, Yongyi, Garcia, Joe G.N., Chapman, Eli, Kiela, Pawel R., Zhang, Qing-Yu, White, Eileen, Ding, Xinxin, Ooi, Aikseng, Zhang, Donna D.
Publicado 2021

Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

por Sivinski, Jared, Ambrose, Andrew J., Panfilenko, Iliya, Zerio, Christopher J., Machulis, Jason M., Mollasalehi, Niloufar, Kaneko, Lynn K., Stevens, Mckayla, Ray, Anne-Marie, Park, Yangshin, Wu, Chunxiang, Hoang, Quyen Q., Johnson, Steven M., Chapman, Eli
Publicado 2021

NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8

por Anandhan, Annadurai, Dodson, Matthew, Shakya, Aryatara, Chen, Jinjing, Liu, Pengfei, Wei, Yongyi, Tan, Hui, Wang, Qian, Jiang, Ziyan, Yang, Kevin, Garcia, Joe GN, Chambers, Setsuko K., Chapman, Eli, Ooi, Aikseng, Yang-Hartwich, Yang, Stockwell, Brent R., Zhang, Donna D.
Publicado 2023