Importance of lysosomal cysteine proteases in lung disease

por Wolters, Paul J, Chapman, Harold A
Publicado 2000

A Role for Caveolin and the Urokinase Receptor in Integrin-mediated Adhesion and Signaling

por Wei, Ying, Yang, Xiuwei, Liu, Qiumei, Wilkins, John A., Chapman, Harold A.
Publicado 1999

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism

por Villadangos, José A., Riese, Richard J., Peters, Christoph, Chapman, Harold A., Ploegh, Hidde L.
Publicado 1997

A MusD Retrotransposon Insertion in the Mouse Slc6a5 Gene Causes Alterations in Neuromuscular Junction Maturation and Behavioral Phenotypes

por Bogdanik, Laurent P., Chapman, Harold D., Miers, Kathy E., Serreze, David V., Burgess, Robert W.
Publicado 2012

Matrilysin-dependent Elastolysis by Human Macrophages

por Filippov, Sergey, Caras, Ingrid, Murray, Richard, Matrisian, Lynn M., Chapman, Harold A., Shapiro, Steven, Weiss, Stephen J.
Publicado 2003

Idd9/11 Genetic Locus Regulates Diabetogenic Activity of CD4 T-Cells in Nonobese Diabetic (NOD) Mice

por Chen, Yi-Guang, Scheuplein, Felix, Osborne, Melissa A., Tsaih, Shirng-Wern, Chapman, Harold D., Serreze, David V.
Publicado 2008

Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

por Kim, Young, Kugler, Matthias C., Wei, Ying, Kim, Kevin K., Li, Xiaopeng, Brumwell, Alexis N., Chapman, Harold A.
Publicado 2009

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

por Zhang, Feng, Tom, Clifford C., Kugler, Matthias C., Ching, Tsui-Ting, Kreidberg, Jordan A., Wei, Ying, Chapman, Harold A.
Publicado 2003

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

por Ewald, Sarah E., Lee, Bettina L., Lau, Laura, Wickliffe, Katherine E., Shi, Guo-Ping, Chapman, Harold A., Barton, Gregory M.
Publicado 2008

Interferon γ Induction of Pulmonary Emphysema in the Adult Murine Lung

por Wang, Zhongde, Zheng, Tao, Zhu, Zhou, Homer, Robert J., Riese, Richard J., Chapman, Harold A., Shapiro, Steven D., Elias, Jack A.
Publicado 2000

Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages

por Shi, Guo-Ping, Bryant, Rebecca A.R., Riese, Richard, Verhelst, Steven, Driessen, Christoph, Li, Zhenqiang, Bromme, Dieter, Ploegh, Hidde L., Chapman, Harold A.
Publicado 2000

Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies

por Serreze, David V., Chapman, Harold D., Niens, Marijke, Dunn, Robert, Kehry, Marilyn R., Driver, John P., Haller, Michael, Wasserfall, Clive, Atkinson, Mark A.
Publicado 2011

Regulation of α5β1 integrin conformation and function by urokinase receptor binding

por Wei, Ying, Czekay, Ralf-Peter, Robillard, Liliane, Kugler, Matthias C., Zhang, Feng, Kim, Kevin K., Xiong, Jian-ping, Humphries, Martin J., Chapman, Harold A.
Publicado 2005

Cathepsin S Controls the Trafficking and Maturation of Mhc Class II Molecules in Dendritic Cells

por Driessen, Christoph, Bryant, Rebecca A.R., Lennon-Duménil, Ana-Maria, Villadangos, José A., Bryant, Paula Wolf, Shi, Guo-Ping, Chapman, Harold A., Ploegh, Hidde L.
Publicado 1999

Small molecule inhibition of IRE1α kinase/RNase has anti-fibrotic effects in the lung

por Thamsen, Maike, Ghosh, Rajarshi, Auyeung, Vincent C., Brumwell, Alexis, Chapman, Harold A., Backes, Bradley J., Perara, Gayani, Maly, Dustin J., Sheppard, Dean, Papa, Feroz R.
Publicado 2019

A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis

por Cohen, Max L., Brumwell, Alexis N., Che Ho, Tsung, Montas, Genevieve, Golden, Jeffrey A., Jones, Kirk D., Wolters, Paul J., Wei, Ying, Chapman, Harold A., Le Saux, Claude J.
Publicado 2023

B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes

por Egia-Mendikute, Leire, Arpa, Berta, Rosell-Mases, Estela, Corral-Pujol, Marta, Carrascal, Jorge, Carrillo, Jorge, Mora, Conchi, Chapman, Harold, Panosa, Anaïs, Vives-Pi, Marta, Stratmann, Thomas, Serreze, David, Verdaguer, Joan
Publicado 2019

B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

por Leeth, Caroline M., Racine, Jeremy, Chapman, Harold D., Arpa, Berta, Carrillo, Jorge, Carrascal, Jorge, Wang, Qiming, Ratiu, Jeremy, Egia-Mendikute, Leire, Rosell-Mases, Estela, Stratmann, Thomas, Verdaguer, Joan, Serreze, David V.
Publicado 2016

Lineage-negative Progenitors Mobilize to Regenerate Lung Epithelium after Major Injury

por Vaughan, Andrew E., Brumwell, Alexis N., Xi, Ying, Gotts, Jeffrey, Brownfield, Doug G., Treutlein, Barbara, Tan, Kevin, Tan, Victor, Liu, Fengchun, Looney, Mark R., Matthay, Michael, Rock, Jason R., Chapman, Harold A.
Publicado 2014

Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells

por Kathiriya, Jaymin J., Wang, Chaoqun, Zhou, Minqi, Brumwell, Alexis, Cassandras, Monica, Le Saux, Claude, Cohen, Max, Alysandratos, Kostantinos-Dionysios, Wang, Bruce, Wolters, Paul, Matthay, Michael, Kotton, Darrell N., Chapman, Harold A, Peng, Tien
Publicado 2022