Innate sensing of viral infection by pDCs and regulation by IFN-α and HMGB1 of TRAIL expression on pDCs and NK cells

por Saïdi, Héla, Bras, Marlène, Formaglio, Pauline, Charbit, Bruno, Herbeuval, Jean-Philippe, Gougeon, Marie-Lise
Publicado 2014

HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells

por Saïdi, Héla, Bras, Marlène, Formaglio, Pauline, Melki, Marie-Thérèse, Charbit, Bruno, Herbeuval, Jean-Philippe, Gougeon, Marie-Lise
Publicado 2016

Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus

por Sugrue, Jamie A., Smith, Megan, Posseme, Celine, Charbit, Bruno, Bourke, Nollaig M., Duffy, Darragh, O’Farrelly, Cliona
Publicado 2022

Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes

por Caron, Barthelemy, Patin, Etienne, Rotival, Maxime, Charbit, Bruno, Albert, Matthew L., Quintana-Murci, Lluis, Duffy, Darragh, Rausell, Antonio
Publicado 2022

Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort

por Sugrue, Jamie A., Posseme, Céline, Tan, Ziyang, Pou, Christian, Charbit, Bruno, Bondet, Vincent, Bourke, Nollaig M., Brodin, Petter, Duffy, Darragh, O’Farrelly, Cliona
Publicado 2022

Human genetic variants and age are the strongest predictors of humoral immune responses to common pathogens and vaccines

por Scepanovic, Petar, Alanio, Cécile, Hammer, Christian, Hodel, Flavia, Bergstedt, Jacob, Patin, Etienne, Thorball, Christian W., Chaturvedi, Nimisha, Charbit, Bruno, Abel, Laurent, Quintana-Murci, Lluis, Duffy, Darragh, Albert, Matthew L., Fellay, Jacques
Publicado 2018

Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers

por Byrd, Allyson L., Liu, Menghan, Fujimura, Kei E., Lyalina, Svetlana, Nagarkar, Deepti R., Charbit, Bruno, Bergstedt, Jacob, Patin, Etienne, Harrison, Oliver J., Quintana-Murci, Lluís, Mellman, Ira, Duffy, Darragh, Albert, Matthew L.
Publicado 2020

Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients

por Courties, Alice, Boussier, Jeremy, Hadjadj, Jérôme, Yatim, Nader, Barnabei, Laura, Péré, Hélène, Veyer, David, Kernéis, Solen, Carlier, Nicolas, Pène, Frédéric, Rieux-Laucat, Frédéric, Charbit, Bruno, Bondet, Vincent, Duffy, Darragh, Berenbaum, Francis, Terrier, Benjamin, Sellam, Jérémie
Publicado 2021

Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks

por Villain, Etienne, Chanson, Aurélie, Mainka, Malwina, Kampschulte, Nadja, Le Faouder, Pauline, Bertrand-Michel, Justine, Brandolini-Bulon, Marion, Charbit, Bruno, Musvosvi, Munyaradzi, Bilek, Nicole, Scriba, Thomas J., Quintana-Murci, Lluis, Schebb, Nils Helge, Duffy, Darragh, Gladine, Cécile
Publicado 2023

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

por Piasecka, Barbara, Duffy, Darragh, Urrutia, Alejandra, Quach, Hélène, Patin, Etienne, Posseme, Céline, Bergstedt, Jacob, Charbit, Bruno, Rouilly, Vincent, MacPherson, Cameron R., Hasan, Milena, Albaud, Benoit, Gentien, David, Fellay, Jacques, Albert, Matthew L., Quintana-Murci, Lluis
Publicado 2018

Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

por Boussier, Jeremy, Yatim, Nader, Marchal, Armance, Hadjadj, Jérôme, Charbit, Bruno, El Sissy, Carine, Carlier, Nicolas, Pène, Frédéric, Mouthon, Luc, Tharaux, Pierre-Louis, Bergeron, Anne, Smadja, David M., Rieux-Laucat, Frédéric, Duffy, Darragh, Kernéis, Solen, Frémeaux-Bacchi, Véronique, Terrier, Benjamin
Publicado 2022

Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection

por Duffy, Darragh, Nemes, Elisa, Llibre, Alba, Rouilly, Vincent, Musvosvi, Munyaradzi, Smith, Nikaïa, Filander, Elizabeth, Africa, Hadn, Mabwe, Simbarashe, Jaxa, Lungisa, Charbit, Bruno, Mulenga, Humphrey, Tameris, Michele, Walzl, Gerhard, Malherbe, Stephanus, Thomas, Stephanie, Hatherill, Mark, Bilek, Nicole, Scriba, Thomas J, Albert, Matthew L
Publicado 2020

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses

por Llibre, Alba, Smith, Nikaïa, Rouilly, Vincent, Musvosvi, Munyaradzi, Nemes, Elisa, Posseme, Céline, Mabwe, Simbarashe, Charbit, Bruno, Mbandi, Stanley Kimbung, Filander, Elizabeth, Africa, Hadn, Saint-André, Violaine, Bondet, Vincent, Bost, Pierre, Mulenga, Humphrey, Bilek, Nicole, Albert, Matthew L., Scriba, Thomas J., Duffy, Darragh
Publicado 2022

Platelet activation in critically ill COVID-19 patients

por Yatim, Nader, Boussier, Jeremy, Chocron, Richard, Hadjadj, Jérôme, Philippe, Aurélien, Gendron, Nicolas, Barnabei, Laura, Charbit, Bruno, Szwebel, Tali-Anne, Carlier, Nicolas, Pène, Frédéric, Azoulay, Célia, Khider, Lina, Mirault, Tristan, Diehl, Jean-Luc, Guerin, Coralie L., Rieux-Laucat, Frédéric, Duffy, Darragh, Kernéis, Solen, Smadja, David M., Terrier, Benjamin
Publicado 2021

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

por Smith, Nikaïa, Goncalves, Pedro, Charbit, Bruno, Grzelak, Ludivine, Beretta, Maxime, Planchais, Cyril, Bruel, Timothée, Rouilly, Vincent, Bondet, Vincent, Hadjadj, Jérôme, Yatim, Nader, Pere, Helene, Merkling, Sarah H., Ghozlane, Amine, Kernéis, Solen, Rieux-Laucat, Frederic, Terrier, Benjamin, Schwartz, Olivier, Mouquet, Hugo, Duffy, Darragh, Di Santo, James P.
Publicado 2021

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

por Posseme, Celine, Llibre, Alba, Charbit, Bruno, Bondet, Vincent, Rouilly, Vincent, Saint-André, Violaine, Boussier, Jeremy, Bergstedt, Jacob, Smith, Nikaïa, Townsend, Liam, Sugrue, Jamie A., Ní Cheallaigh, Clíona, Conlon, Niall, Rotival, Maxime, Kobor, Michael S., Mottez, Estelle, Pol, Stanislas, Patin, Etienne, Albert, Matthew L., Quintana-Murci, Lluis, Duffy, Darragh
Publicado 2022

Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients

por Smadja, David M., Guerin, Coralie L., Chocron, Richard, Yatim, Nader, Boussier, Jeremy, Gendron, Nicolas, Khider, Lina, Hadjadj, Jérôme, Goudot, Guillaume, Debuc, Benjamin, Juvin, Philippe, Hauw-Berlemont, Caroline, Augy, Jean-Loup, Peron, Nicolas, Messas, Emmanuel, Planquette, Benjamin, Sanchez, Olivier, Charbit, Bruno, Gaussem, Pascale, Duffy, Darragh, Terrier, Benjamin, Mirault, Tristan, Diehl, Jean-Luc
Publicado 2020

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment

por Smith, Nikaïa, Rodero, Mathieu P., Bekaddour, Nassima, Bondet, Vincent, Ruiz-Blanco, Yasser B., Harms, Mirja, Mayer, Benjamin, Bader-Meunier, Brigitte, Quartier, Pierre, Bodemer, Christine, Baudouin, Véronique, Dieudonné, Yannick, Kirchhoff, Frank, Sanchez Garcia, Elsa, Charbit, Bruno, Leboulanger, Nicolas, Jahrsdörfer, Bernd, Richard, Yolande, Korganow, Anne-Sophie, Münch, Jan, Nisole, Sébastien, Duffy, Darragh, Herbeuval, Jean-Philippe
Publicado 2019

Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity

por Smith, Nikaïa, Possémé, Céline, Bondet, Vincent, Sugrue, Jamie, Townsend, Liam, Charbit, Bruno, Rouilly, Vincent, Saint-André, Violaine, Dott, Tom, Pozo, Andre Rodriguez, Yatim, Nader, Schwartz, Olivier, Cervantes-Gonzalez, Minerva, Ghosn, Jade, Bastard, Paul, Casanova, Jean Laurent, Szwebel, Tali-Anne, Terrier, Benjamin, Conlon, Niall, O’Farrelly, Cliona, Cheallaigh, Clíona Ní, Bourke, Nollaig M., Duffy, Darragh
Publicado 2022

Variability of Primary Sjögren's Syndrome Is Driven by Interferon‐α and Interferon‐α Blood Levels Are Associated With the Class II HLA–DQ Locus

por Trutschel, Diana, Bost, Pierre, Mariette, Xavier, Bondet, Vincent, Llibre, Alba, Posseme, Celine, Charbit, Bruno, Thorball, Christian W., Jonsson, Roland, Lessard, Christopher J., Felten, Renaud, Ng, Wan Fai, Chatenoud, Lucienne, Dumortier, Hélène, Sibilia, Jean, Fellay, Jacques, Brokstad, Karl A., Appel, Silke, Tarn, Jessica R., Quintana‐Murci, Lluis, Mingueneau, Michael, Meyer, Nicolas, Duffy, Darragh, Schwikowski, Benno, Gottenberg, Jacques Eric
Publicado 2022