Insights into the Bidirectional Properties of the Sheep–Deer Prion Transmission Barrier

por Harrathi, Chafik, Fernández-Borges, Natalia, Eraña, Hasier, Elezgarai, Saioa R., Venegas, Vanessa, Charco, Jorge M., Castilla, Joaquín
Publicado 2018

Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria

por Bernardo-Seisdedos, Ganeko, Charco, Jorge M., SanJuan, Itxaso, García-Martínez, Sandra, Urquiza, Pedro, Eraña, Hasier, Castilla, Joaquín, Millet, Oscar
Publicado 2021

Recombinant PrP and Its Contribution to Research on Transmissible Spongiform Encephalopathies

por Charco, Jorge M., Eraña, Hasier, Venegas, Vanessa, García-Martínez, Sandra, López-Moreno, Rafael, González-Miranda, Ezequiel, Pérez-Castro, Miguel Ángel, Castilla, Joaquín
Publicado 2017

A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures

por Eraña, Hasier, Pérez-Castro, Miguel Ángel, García-Martínez, Sandra, Charco, Jorge M., López-Moreno, Rafael, Díaz-Dominguez, Carlos M., Barrio, Tomás, González-Miranda, Ezequiel, Castilla, Joaquín
Publicado 2020

Detection of Pathognomonic Biomarker PrP(Sc) and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases

por Eraña, Hasier, Charco, Jorge M., González-Miranda, Ezequiel, García-Martínez, Sandra, López-Moreno, Rafael, Pérez-Castro, Miguel A., Díaz-Domínguez, Carlos M., García-Salvador, Adrián, Castilla, Joaquín
Publicado 2020

Generation of a new infectious recombinant prion: a model to understand Gerstmann–Sträussler–Scheinker syndrome

por Elezgarai, Saioa R., Fernández-Borges, Natalia, Eraña, Hasier, Sevillano, Alejandro M., Charco, Jorge M., Harrathi, Chafik, Saá, Paula, Gil, David, Kong, Qingzhong, Requena, Jesús R., Andréoletti, Olivier, Castilla, Joaquín
Publicado 2017

Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy

por Otero, Alicia, Barrio, Tomás, Eraña, Hasier, Charco, Jorge M., Betancor, Marina, Díaz-Domínguez, Carlos M., Marín, Belén, Andréoletti, Olivier, Torres, Juan M., Kong, Qingzhong, Badiola, Juan J., Bolea, Rosa, Castilla, Joaquín
Publicado 2022

Description of the first Spanish case of Gerstmann–Sträussler–Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization

por Eraña, Hasier, San Millán, Beatriz, Díaz-Domínguez, Carlos M., Charco, Jorge M., Rodríguez, Rosa, Viéitez, Irene, Pereda, Arrate, Yañez, Rosa, Geijo, Mariví, Navarro, Carmen, Perez de Nanclares, Guiomar, Teijeira, Susana, Castilla, Joaquín
Publicado 2022

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear

por Ferreira, Natalia C., Charco, Jorge M., Plagenz, Jakob, Orru, Christina D., Denkers, Nathanial D., Metrick, Michael A., Hughson, Andrew G., Griffin, Karen A., Race, Brent, Hoover, Edward A., Castilla, Joaquín, Nichols, Tracy A., Miller, Michael W., Caughey, Byron
Publicado 2021

Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease

por Ximelis, Teresa, Marín-Moreno, Alba, Espinosa, Juan Carlos, Eraña, Hasier, Charco, Jorge M., Hernández, Isabel, Riveira, Carmen, Alcolea, Daniel, González-Roca, Eva, Aldecoa, Iban, Molina-Porcel, Laura, Parchi, Piero, Rossi, Marcello, Castilla, Joaquín, Ruiz-García, Raquel, Gelpi, Ellen, Torres, Juan María, Sánchez-Valle, Raquel
Publicado 2021

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies

por Eraña, Hasier, Charco, Jorge M., Di Bari, Michele A., Díaz-Domínguez, Carlos M., López-Moreno, Rafael, Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A., García-Martínez, Sandra, Bravo, Susana, Fernández-Borges, Natalia, Geijo, Mariví, D’Agostino, Claudia, Garrido, Joseba, Bian, Jifeng, König, Anna, Uluca-Yazgi, Boran, Sabate, Raimon, Khaychuk, Vadim, Vanni, Ilaria, Telling, Glenn C., Heise, Henrike, Nonno, Romolo, Requena, Jesús R., Castilla, Joaquín
Publicado 2019

Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model

por Vidal, Enric, Sánchez-Martín, Manuel A., Eraña, Hasier, Lázaro, Sonia Pérez, Pérez-Castro, Miguel A., Otero, Alicia, Charco, Jorge M., Marín, Belén, López-Moreno, Rafael, Díaz-Domínguez, Carlos M., Geijo, Mariví, Ordóñez, Montserrat, Cantero, Guillermo, di Bari, Michele, Lorenzo, Nuria L., Pirisinu, Laura, d’Agostino, Claudia, Torres, Juan María, Béringue, Vincent, Telling, Glenn, Badiola, Juan J., Pumarola, Martí, Bolea, Rosa, Nonno, Romolo, Requena, Jesús R., Castilla, Joaquín
Publicado 2022

Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation

por Eraña, Hasier, Díaz-Domínguez, Carlos M., Charco, Jorge M., Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A., Piñeiro, Patricia, López-Moreno, Rafael, Sampedro-Torres-Quevedo, Cristina, Fernández-Veiga, Leire, Tasis-Galarza, Juan, Lorenzo, Nuria L., Santini-Santiago, Aileen, Lázaro, Melisa, García-Martínez, Sandra, Gonçalves-Anjo, Nuno, San-Juan-Ansoleaga, Maitena, Galarza-Ahumada, Josu, Fernández-Muñoz, Eva, Giler, Samanta, Valle, Mikel, Telling, Glenn C., Geijó, Mariví, Requena, Jesús R., Castilla, Joaquín
Publicado 2023