Clean single-valued polylogarithms

por Charlton, Steven, Duhr, Claude, Gangl, Herbert
Publicado 2021

Airway remodeling disease: primary human structural cells and phenotypic and pathway assays to identify targets with potential to prevent or reverse remodeling

por Rosethorne, Elizabeth M, Charlton, Steven J
Publicado 2018

Micro-pharmacokinetics: Quantifying local drug concentration at live cell membranes

por Gherbi, Karolina, Briddon, Stephen J., Charlton, Steven J.
Publicado 2018

Functional desensitization of the β(2) adrenoceptor is not dependent on agonist efficacy

por Rosethorne, Elizabeth M, Bradley, Michelle E, Kent, Toby C, Charlton, Steven J
Publicado 2015

The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

por Roberts, Maxine J., Broome, Rebecca E., Kent, Toby C., Charlton, Steven J., Rosethorne, Elizabeth M.
Publicado 2018

Reply to ‘Antipsychotics with similar association kinetics at dopamine D(2) receptors differ in extrapyramidal side-effects’

por Sykes, David A., Lane, J. Robert, Szabo, Monika, Capuano, Ben, Javitch, Jonathan A., Charlton, Steven J.
Publicado 2018

Exploring the kinetic selectivity of drugs targeting the β(1)‐adrenoceptor

por Sykes, David A., Jiménez‐Rosés, Mireia, Reilly, John, Fairhurst, Robin A., Charlton, Steven J., Veprintsev, Dmitry B.
Publicado 2022

Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D(2) receptors

por Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J.
Publicado 2017

The pharmacological rationale for combining muscarinic receptor antagonists and β-adrenoceptor agonists in the treatment of airway and bladder disease()

por Dale, Philippa R, Cernecka, Hana, Schmidt, Martina, Dowling, Mark R, Charlton, Steven J, Pieper, Michael P, Michel, Martin C
Publicado 2014

Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus

por Roberts, Maxine J., May, Lauren T., Keen, Alastair C., Liu, Bonan, Lam, Terrance, Charlton, Steven J., Rosethorne, Elizabeth M., Halls, Michelle L.
Publicado 2021

Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2

por Casella, Bianca Maria, Farmer, James P., Nesheva, Desislava N., Williams, Huw E. L., Charlton, Steven J., Holliday, Nicholas D., Laughton, Charles A., Mistry, Shailesh N.
Publicado 2023

Interaction With the Lipid Membrane Influences Fentanyl Pharmacology

por Sutcliffe, Katy J., Corey, Robin A, Alhosan, Norah, Cavallo, Damiana, Groom, Sam, Santiago, Marina, Bailey, Chris, Charlton, Steven J., Sessions, Richard B., Henderson, Graeme, Kelly, Eamonn
Publicado 2022

Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor

por Yen, Hsin-Yung, Liko, Idlir, Song, Wanling, Kapoor, Parth, Almeida, Fernando, Toporowska, Joanna, Gherbi, Karolina, Hopper, Jonathan T. S., Charlton, Steven J., Politis, Argyris, Sansom, Mark S. P., Jazayeri, Ali, Robinson, Carol V.
Publicado 2022

The role of kinetic context in apparent biased agonism at GPCRs

por Klein Herenbrink, Carmen, Sykes, David A., Donthamsetti, Prashant, Canals, Meritxell, Coudrat, Thomas, Shonberg, Jeremy, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Charlton, Steven J., Javitch, Jonathan A., Christopoulos, Arthur, Lane, J. Robert
Publicado 2016

High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function

por Bill, Anke, Rosethorne, Elizabeth M., Kent, Toby C., Fawcett, Lindsay, Burchell, Lynn, van Diepen, Michiel T., Marelli, Anthony, Batalov, Sergey, Miraglia, Loren, Orth, Anthony P., Renaud, Nicole A., Charlton, Steven J., Gosling, Martin, Gaither, L. Alex, Groot-Kormelink, Paul J.
Publicado 2014