Aubergine and piRNAs promote germline stem cell self‐renewal by repressing the proto‐oncogene Cbl

por Rojas‐Ríos, Patricia, Chartier, Aymeric, Pierson, Stéphanie, Simonelig, Martine
Publicado 2017

The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response

por Naït-Saïdi, Rima, Chartier, Aymeric, Abgueguen, Emmanuelle, Guédat, Philippe, Simonelig, Martine
Publicado 2023

The CCR4 Deadenylase Acts with Nanos and Pumilio in the Fine-Tuning of Mei-P26 Expression to Promote Germline Stem Cell Self-Renewal

por Joly, Willy, Chartier, Aymeric, Rojas-Rios, Patricia, Busseau, Isabelle, Simonelig, Martine
Publicado 2013

RNF219 regulates CCR4-NOT function in mRNA translation and deadenylation

por Guénolé, Aude, Velilla, Fabien, Chartier, Aymeric, Rich, April, Carvunis, Anne-Ruxandra, Sardet, Claude, Simonelig, Martine, Sobhian, Bijan
Publicado 2022

Antiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy

por Barbezier, Nicolas, Chartier, Aymeric, Bidet, Yannick, Buttstedt, Anja, Voisset, Cécile, Galons, Hervé, Blondel, Marc, Schwarz, Elisabeth, Simonelig, Martine
Publicado 2011

Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy

por Ribot, Cécile, Soler, Cédric, Chartier, Aymeric, Al Hayek, Sandy, Naït-Saïdi, Rima, Barbezier, Nicolas, Coux, Olivier, Simonelig, Martine
Publicado 2022

piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm

por Dufourt, Jérémy, Bontonou, Gwénaëlle, Chartier, Aymeric, Jahan, Camille, Meunier, Anne-Cécile, Pierson, Stéphanie, Harrison, Paul F., Papin, Catherine, Beilharz, Traude H., Simonelig, Martine
Publicado 2017

The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm

por Ramat, Anne, Garcia-Silva, Maria-Rosa, Jahan, Camille, Naït-Saïdi, Rima, Dufourt, Jérémy, Garret, Céline, Chartier, Aymeric, Cremaschi, Julie, Patel, Vipul, Decourcelle, Mathilde, Bastide, Amandine, Juge, François, Simonelig, Martine
Publicado 2020

Deregulation of the ubiquitin-proteasome system is the predominant molecular pathology in OPMD animal models and patients

por Anvar, Seyed Yahya, 't Hoen, Peter AC, Venema, Andrea, van der Sluijs, Barbara, van Engelen, Baziel, Snoeck, Marc, Vissing, John, Trollet, Capucine, Dickson, George, Chartier, Aymeric, Simonelig, Martine, van Ommen, Gert-Jan B, van der Maarel, Silvere M, Raz, Vered
Publicado 2011

Mitochondrial Dysfunction Reveals the Role of mRNA Poly(A) Tail Regulation in Oculopharyngeal Muscular Dystrophy Pathogenesis

por Chartier, Aymeric, Klein, Pierre, Pierson, Stéphanie, Barbezier, Nicolas, Gidaro, Teresa, Casas, François, Carberry, Steven, Dowling, Paul, Maynadier, Laurie, Bellec, Maëlle, Oloko, Martine, Jardel, Claude, Moritz, Bodo, Dickson, George, Mouly, Vincent, Ohlendieck, Kay, Butler-Browne, Gillian, Trollet, Capucine, Simonelig, Martine
Publicado 2015