Combination treatment of an IDH1 inhibitor with chemotherapy in IDH1 mutant acute myeloid leukemia

por Gupta, Charu, Kaulfuss, Stefan, Görlich, Kerstin, Othman, Basem, Chaturvedi, Anuhar, Heuser, Michael
Publicado 2020

Activation of TRKA receptor elicits mastocytosis in mice and is involved in the development of resistance to KIT-targeted therapy

por Yang, Min, Pan, Zengkai, Huang, Kezhi, Büsche, Guntram, Feuerhake, Friedrich, Chaturvedi, Anuhar, Nie, Danian, Heuser, Michael, Thol, Felicitas, von Neuhoff, Nils, Ganser, Arnold, Li, Zhixiong
Publicado 2017

Genetic Deletion of SEPT7 Reveals a Cell Type-Specific Role of Septins in Microtubule Destabilization for the Completion of Cytokinesis

por Menon, Manoj B., Sawada, Akihiro, Chaturvedi, Anuhar, Mishra, Pooja, Schuster-Gossler, Karin, Galla, Melanie, Schambach, Axel, Gossler, Achim, Förster, Reinhold, Heuser, Michael, Kotlyarov, Alexey, Kinoshita, Makoto, Gaestel, Matthias
Publicado 2014

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators

por Qiu, Jinsong, Zhou, Bing, Thol, Felicitas, Zhou, Yu, Chen, Liang, Shao, Changwei, DeBoever, Christopher, Hou, Jiayi, Li, Hairi, Chaturvedi, Anuhar, Ganser, Arnold, Bejar, Rafael, Zhang, Dong-Er, Fu, Xiang-Dong, Heuser, Michael
Publicado 2016

Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite

por Berger, Raffaela S., Wachsmuth, Christian J., Waldhier, Magdalena C., Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar, Niller, Hans-Helmut, Bumes, Elisabeth, Hau, Peter, Proescholdt, Martin, Gronwald, Wolfram, Heuser, Michael, Kreutz, Marina, Oefner, Peter J., Dettmer, Katja
Publicado 2021

Synergistic activity of IDH1 inhibitor BAY1436032 with azacitidine in IDH1 mutant acute myeloid leukemia

por Chaturvedi, Anuhar, Gupta, Charu, Gabdoulline, Razif, Borchert, Nora M., Goparaju, Ramya, Kaulfuss, Stefan, Gorlich, Kerstin, Schottmann, Renate, Othman, Basem, Welzenbach, Julia, Panknin, Olaf, Wagner, Markus, Geffers, Robert, Ganser, Arnold, Thol, Felicitas, Jeffers, Michael, Haegebarth, Andrea, Heuser, Michael
Publicado 2020

In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site

por Chaturvedi, Anuhar, Goparaju, Ramya, Gupta, Charu, Weder, Julia, Klünemann, Thomas, Araujo Cruz, Michelle Maria, Kloos, Arnold, Goerlich, Kerstin, Schottmann, Renate, Othman, Basem, Struys, Eduard A., Bähre, Heike, Grote-Koska, Denis, Brand, Korbinian, Ganser, Arnold, Preller, Matthias, Heuser, Michael
Publicado 2019

Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody

por Bähr-Mahmud, Hayat, Ellinghaus, Ursula, Stadler, Christiane R., Fischer, Leyla, Lindemann, Claudia, Chaturvedi, Anuhar, Diekmann, Jan, Wöll, Stefan, Biermann, Imke, Hebich, Bernhard, Scharf, Caroline, Siefke, Manuela, Roth, Alexandra S., Rao, Martin, Brettschneider, Kerstin, Ewen, Eva-Maria, Şahin, Uğur, Türeci, Özlem
Publicado 2023

IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction—a retrospective propensity score analysis

por Kattih, Badder, Shirvani, Amir, Klement, Piroska, Garrido, Abel Martin, Gabdoulline, Razif, Liebich, Alessandro, Brandes, Maximilian, Chaturvedi, Anuhar, Seeger, Timon, Thol, Felicitas, Göhring, Gudrun, Schlegelberger, Brigitte, Geffers, Robert, John, David, Bavendiek, Udo, Bauersachs, Johann, Ganser, Arnold, Heineke, Joerg, Heuser, Michael
Publicado 2020

A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation

por Yang, Min, Pan, Zengkai, Huang, Kezhi, Büsche, Guntram, Liu, Hongyun, Göhring, Gudrun, Rumpel, Regina, Dittrich-Breiholz, Oliver, Talbot, Steven, Scherr, Michaela, Chaturvedi, Anuhar, Eder, Matthias, Skokowa, Julia, Zhou, Jianfeng, Welte, Karl, von Neuhoff, Nils, Liu, Ligen, Ganser, Arnold, Li, Zhixiong
Publicado 2021

RNA interference efficiently targets human leukemia driven by a fusion oncogene in vivo

por Jyotsana, Nidhi, Sharma, Amit, Chaturvedi, Anuhar, Scherr, Michaela, Kuchenbauer, Florian, Sajti, Laszlo, Barchanski, Annette, Lindner, Robert, Noyan, Fatih, Sühs, Kurt-Wolfram, Grote-Koska, Denis, Brand, Korbinian, Vornlocher, Hans-Peter, Stanulla, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eder, Matthias, Thol, Felicitas, Ganser, Arnold, Humphries, R. Keith, Ramsay, Euan, Cullis, Pieter, Heuser, Michael
Publicado 2017