Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

por Eram, Mohammad S., Bustos, Susan P., Lima-Fernandes, Evelyne, Siarheyeva, Alena, Senisterra, Guillermo, Hajian, Taraneh, Chau, Irene, Duan, Shili, Wu, Hong, Dombrovski, Ludmila, Schapira, Matthieu, Arrowsmith, Cheryl H., Vedadi, Masoud
Publicado 2014

Crystal structure of SARS‐CoV‐2 nsp10–nsp16 in complex with small molecule inhibitors, SS148 and WZ16

por Klima, Martin, Khalili Yazdi, Aliakbar, Li, Fengling, Chau, Irene, Hajian, Taraneh, Bolotokova, Albina, Kaniskan, H. Ümit, Han, Yulin, Wang, Ke, Li, Deyao, Luo, Minkui, Jin, Jian, Boura, Evzen, Vedadi, Masoud
Publicado 2022

SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses

por Li, Fengling, Ghiabi, Pegah, Hajian, Taraneh, Klima, Martin, Li, Alice Shi Ming, Khalili Yazdi, Aliakbar, Chau, Irene, Loppnau, Peter, Kutera, Maria, Seitova, Almagul, Bolotokova, Albina, Hutchinson, Ashley, Perveen, Sumera, Boura, Evzen, Vedadi, Masoud
Publicado 2023

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

por Devkota, Kanchan, Schapira, Matthieu, Perveen, Sumera, Khalili Yazdi, Aliakbar, Li, Fengling, Chau, Irene, Ghiabi, Pegah, Hajian, Taraneh, Loppnau, Peter, Bolotokova, Albina, Satchell, Karla J.F., Wang, Ke, Li, Deyao, Liu, Jing, Smil, David, Luo, Minkui, Jin, Jian, Fish, Paul V., Brown, Peter J., Vedadi, Masoud
Publicado 2021

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

por Senisterra, Guillermo, Wu, Hong, Allali-Hassani, Abdellah, Wasney, Gregory A., Barsyte-Lovejoy, Dalia, Dombrovski, Ludmila, Dong, Aiping, Nguyen, Kong T., Smil, David, Bolshan, Yuri, Hajian, Taraneh, He, Hao, Seitova, Alma, Chau, Irene, Li, Fengling, Poda, Gennadiy, Couture, Jean-François, Brown, Peter J., Al-Awar, Rima, Schapira, Matthieu, Arrowsmith, Cheryl H., Vedadi, Masoud
Publicado 2012

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors

por Nigam, AkshatKumar, Hurley, Matthew F. D., Li, Fengling, Konkoǐová, Eva, Klíma, Martin, Trylčová, Jana, Pollice, Robert, Çinaroǧlu, Süleyman Selim, Levin-Konigsberg, Roni, Handjaya, Jasemine, Schapira, Matthieu, Chau, Irene, Perveen, Sumera, Ng, Ho-Leung, Ümit Kaniskan, H., Han, Yulin, Singh, Sukrit, Gorgulla, Christoph, Kundaje, Anshul, Jin, Jian, Voelz, Vincent A., Weber, Jan, Nencka, Radim, Boura, Evzen, Vedadi, Masoud, Aspuru-Guzik, Alán
Publicado 2023

The Cryptosporidium parvum Kinome

por Artz, Jennifer D, Wernimont, Amy K, Allali-Hassani, Abdellah, Zhao, Yong, Amani, Mehrnaz, Lin, Yu-Hui, Senisterra, Guillermo, Wasney, Gregory A, Fedorov, Oleg, King, Oliver, Roos, Annette, Lunin, Vlad V, Qiu, Wei, Finerty, Patrick, Hutchinson, Ashley, Chau, Irene, von Delft, Frank, MacKenzie, Farrell, Lew, Jocelyne, Kozieradzki, Ivona, Vedadi, Masoud, Schapira, Matthieu, Zhang, Chao, Shokat, Kevan, Heightman, Tom, Hui, Raymond
Publicado 2011