Arsenite Effects on Mitochondrial Bioenergetics in Human and Mouse Primary Hepatocytes Follow a Nonlinear Dose Response

por Chavan, Hemantkumar, Christudoss, Pamela, Mickey, Kristen, Tessman, Robert, Ni, Hong-min, Swerdlow, Russell, Krishnamurthy, Partha
Publicado 2017

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1–AKT–mTOR Axis in Mice

por Wang, Yifeng, Ding, Yifeng, Li, Jibiao, Chavan, Hemantkumar, Matye, David, Ni, Hong-Min, Chiang, John Y.L., Krishnamurthy, Partha, Ding, Wen-Xing, Li, Tiangang
Publicado 2016

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

por Wang, Hua, Ni, Hong-Min, Chao, Xiaojuan, Ma, Xiaowen, Rodriguez, Yssa Ann, Chavan, Hemantkumar, Wang, Shaogui, Krishnamurthy, Partha, Dobrowsky, Rick, Xu, De-Xiang, Jaeschke, Hartmut, Ding, Wen-Xing
Publicado 2019

Lack of Toxicity in Nonhuman Primates Receiving Clinically Relevant Doses of an AAV9.U7snRNA Vector Designed to Induce DMD Exon 2 Skipping

por Gushchina, Liubov V., Frair, Emma C., Rohan, Natalie, Bradley, Adrienne J., Simmons, Tabatha R., Chavan, Hemantkumar D., Chou, Hsin-Jung, Eggers, Michelle, Waldrop, Megan A., Wein, Nicolas, Flanigan, Kevin M.
Publicado 2021

Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice

por Qin, Xuan, Hakenjos, John M., MacKenzie, Kevin R., Barzi, Mercedes, Chavan, Hemantkumar, Nyshadham, Pranavanand, Wang, Jin, Jung, Sung Yun, Guner, Joie Z., Chen, Si, Guo, Lei, Krishnamurthy, Partha, Bissig, Karl-Dimiter, Palmer, Stephen, Matzuk, Martin M., Li, Feng
Publicado 2022

A Novel Flow Cytometric HTS Assay Reveals Functional Modulators of ATP Binding Cassette Transporter ABCB6

por Polireddy, Kishore, Khan, Mohiuddin Md. Taimur, Chavan, Hemantkumar, Young, Susan, Ma, Xiaochao, Waller, Anna, Garcia, Matthew, Perez, Dominique, Chavez, Stephanie, Strouse, Jacob J., Haynes, Mark K., Bologa, Cristian G., Oprea, Tudor I., Tegos, George P., Sklar, Larry A., Krishnamurthy, Partha
Publicado 2012