PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model

por Chavez, James S., Rabe, Jennifer L., Hernandez, Giovanny, Mills, Taylor S., Niño, Katia E., Davizon-Castillo, Pavel, Pietras, Eric M.
Publicado 2022

PU.1 is required to restrain myelopoiesis during chronic inflammatory stress

por Chavez, James S., Rabe, Jennifer L., Niño, Katia E., Wells, Harrison H., Gessner, Rachel L., Mills, Taylor S., Hernandez, Giovanny, Pietras, Eric M.
Publicado 2023

Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors

por Higa, Kelly C., Goodspeed, Andrew, Chavez, James S., De Dominici, Marco, Danis, Etienne, Zaberezhnyy, Vadym, Rabe, Jennifer L., Tenen, Daniel G., Pietras, Eric M., DeGregori, James
Publicado 2021

Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation

por Ahmed, Nouraiz, Etzrodt, Martin, Dettinger, Philip, Kull, Tobias, Loeffler, Dirk, Hoppe, Philipp S., Chavez, James S., Zhang, Yang, Camargo Ortega, Germán, Hilsenbeck, Oliver, Nakajima, Hideaki, Pietras, Eric M., Schroeder, Timm
Publicado 2021

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis

por Hernandez, Giovanny, Mills, Taylor S., Rabe, Jennifer L., Chavez, James S., Kuldanek, Susan, Kirkpatrick, Gregory, Noetzli, Leila, Jubair, Widian K., Zanche, Michelle, Myers, Jason R., Stevens, Brett M., Fleenor, Courtney J., Adane, Biniam, Dinarello, Charles A., Ashton, John, Jordan, Craig T., Di Paola, Jorge, Hagman, James R., Holers, V. Michael, Kuhn, Kristine A., Pietras, Eric M.
Publicado 2020

PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress

por Chavez, James S., Rabe, Jennifer L., Loeffler, Dirk, Higa, Kelly C., Hernandez, Giovanny, Mills, Taylor S., Ahmed, Nouraiz, Gessner, Rachel L., Ke, Zhonghe, Idler, Beau M., Niño, Katia E., Kim, Hyunmin, Myers, Jason R., Stevens, Brett M., Davizon-Castillo, Pavel, Jordan, Craig T., Nakajima, Hideaki, Ashton, John, Welner, Robert S., Schroeder, Timm, DeGregori, James, Pietras, Eric M.
Publicado 2021