An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition

por Chawla, Ayesha T., Cororaton, Agnes D., Idowu, Michael O., Damle, Priyadarshan K., Szomju, Barbara, Ellis, Keith C., Patel, Bhaumik B., Grossman, Steven R.
Publicado 2018

Transforming activity and therapeutic targeting of C-terminal Binding Protein 2 in Apc mutated neoplasia

por Sumner, Evan T., Chawla, Ayesha T., Cororaton, Agnes D., Koblinski, Jennifer, Kovi, Ramesh C., Love, Ian M., Szomju, Barbara B., Korwar, Sudha, Ellis, Keith C., Grossman, Steven R.
Publicado 2017

MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma

por Floros, Konstantinos V., Chawla, Ayesha T., Johnson-Berro, Mia O., Khatri, Rishabh, Stamatouli, Angeliki M., Boikos, Sosipatros A., Dozmorov, Mikhail G., Cowart, L. Ashley, Faber, Anthony C.
Publicado 2022

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis

por Ding, Boxiao, Haidurov, Alexander, Chawla, Ayesha, Parmigiani, Anita, van de Kamp, Gerarda, Dalina, Alexandra, Yuan, Fang, Lee, Jun Hee, Chumakov, Peter M., Grossman, Steven R., Budanov, Andrei V.
Publicado 2019

CtBP—a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma

por Chawla, Ayesha T., Chougoni, Kranthi Kumar, Joshi, Prashant J., Cororaton, Agnes D., Memari, Patrick, Stansfield, John C., Park, Haemin, Seth, Rashmi, Szomju, Barbara, Sima, Adam P., Idowu, Michael O., Ellis, Keith C., Grossman, Steven R.
Publicado 2019

Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1

por Kurupi, Richard, Floros, Konstantinos V., Jacob, Sheeba, Chawla, Ayesha T., Cai, Jinyang, Hu, Bin, Puchalapalli, Madhavi, Coon, Colin M., Khatri, Rishabh, Crowther, Giovanna Stein, Egan, Regina K., Murchie, Ellen, Greninger, Patricia, Dalton, Krista M., Ghotra, Maninderjit S., Boikos, Sosipatros A., Koblinski, Jennifer E., Harada, Hisashi, Sun, Yue, Morgan, Iain M., Basu, Devraj, Dozmorov, Mikhail G., Benes, Cyril H., Faber, Anthony C.
Publicado 2022