Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives

por Pompeo, Matthew M., Cheah, Jaime H., Movassaghi, Mohammad
Publicado 2019

Synthesis of Potent Cytotoxic Epidithiodiketopiperazines Designed for Derivatization

por Olsson, Chase R., Payette, Joshua N., Cheah, Jaime H., Movassaghi, Mohammad
Publicado 2020

High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming

por Hu, Guangan, Su, Yang, Kang, Byong Ha, Fan, Zhongqi, Dong, Ting, Brown, Douglas R., Cheah, Jaime, Wittrup, Karl Dane, Chen, Jianzhu
Publicado 2021

NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

por Adams, Drew J., Ito, Daisuke, Rees, Matthew G., Seashore-Ludlow, Brinton, Puyang, Xiaoling, Ramos, Alex H., Cheah, Jaime H., Clemons, Paul A., Warmuth, Markus, Zhu, Ping, Shamji, Alykhan F., Schreiber, Stuart L.
Publicado 2014

Discovery of a Small-Molecule Probe for V-ATPase Function

por Aldrich, Leslie N., Kuo, Szu-Yu, Castoreno, Adam B., Goel, Gautam, Kuballa, Petric, Rees, Matthew G., Seashore-Ludlow, Brinton A., Cheah, Jaime H., Latorre, Isabel J., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Publicado 2015

Compressed phenotypic screens for complex multicellular models and high-content assays

por Mead, Benjamin E., Kummerlowe, Conner, Liu, Nuo, Kattan, Walaa E., Cheng, Thomas, Cheah, Jaime H., Soule, Christian K., Peters, Josh, Lowder, Kristen E., Blainey, Paul C., Hahn, William C., Cleary, Brian, Bryson, Bryan, Winter, Peter S., Raghavan, Srivatsan, Shalek, Alex K.
Publicado 2023

A genetic basis for the variation in the vulnerability of cancer to DNA damage

por Yard, Brian D., Adams, Drew J., Chie, Eui Kyu, Tamayo, Pablo, Battaglia, Jessica S., Gopal, Priyanka, Rogacki, Kevin, Pearson, Bradley E., Phillips, James, Raymond, Daniel P., Pennell, Nathan A., Almeida, Francisco, Cheah, Jaime H., Clemons, Paul A., Shamji, Alykhan, Peacock, Craig D., Schreiber, Stuart L., Hammerman, Peter S., Abazeed, Mohamed E.
Publicado 2016

Computationally guided high-throughput design of self-assembling drug nanoparticles

por Reker, Daniel, Rybakova, Yulia, Kirtane, Ameya R., Cao, Ruonan, Yang, Jee Won, Navamajiti, Natsuda, Gardner, Apolonia, Zhang, Rosanna M., Esfandiary, Tina, L’Heureux, Johanna, von Erlach, Thomas, Smekalova, Elena M., Leboeuf, Dominique, Hess, Kaitlyn, Lopes, Aaron, Rogner, Jaimie, Collins, Joy, Tamang, Siddartha M., Ishida, Keiko, Chamberlain, Paul, Yun, DongSoo, Lytoon-Jean, Abigail, Soule, Christian K., Cheah, Jaime H., Hayward, Alison M., Langer, Robert, Traverso, Giovanni
Publicado 2021

Correlating chemical sensitivity and basal gene expression reveals mechanism of action

por Rees, Matthew G., Seashore-Ludlow, Brinton, Cheah, Jaime H., Adams, Drew J., Price, Edmund V., Gill, Shubhroz, Javaid, Sarah, Coletti, Matthew E., Jones, Victor L., Bodycombe, Nicole E., Soule, Christian K., Alexander, Benjamin, Li, Ava, Montgomery, Philip, Kotz, Joanne D., Hon, C. Suk-Yee, Munoz, Benito, Liefeld, Ted, Dančík, Vlado, Haber, Daniel A., Clish, Clary B., Bittker, Joshua A., Palmer, Michelle, Wagner, Bridget K., Clemons, Paul A., Shamji, Alykhan F., Schreiber, Stuart L.
Publicado 2015

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

por Abbott, Keene L., Ali, Ahmed, Casalena, Dominick, Do, Brian T., Ferreira, Raphael, Cheah, Jaime H., Soule, Christian K., Deik, Amy, Kunchok, Tenzin, Schmidt, Daniel R., Renner, Steffen, Honeder, Sophie E., Wu, Michelle, Chan, Sze Ham, Tseyang, Tenzin, Greaves, Daniel, Hsu, Peggy P., Ng, Christopher W., Zhang, Chelsea J., Farsidjani, Ali, Gramatikov, Iva Monique T., Matheson, Nicholas J., Lewis, Caroline A., Clish, Clary B., Rees, Matthew G., Roth, Jennifer A., Griner, Lesley Mathews, Muir, Alexander, Auld, Douglas S., Heiden, Matthew G. Vander
Publicado 2023

Integrated genetic and pharmacologic interrogation of rare cancers

por Hong, Andrew L., Tseng, Yuen-Yi, Cowley, Glenn S., Jonas, Oliver, Cheah, Jaime H., Kynnap, Bryan D., Doshi, Mihir B., Oh, Coyin, Meyer, Stephanie C., Church, Alanna J., Gill, Shubhroz, Bielski, Craig M., Keskula, Paula, Imamovic, Alma, Howell, Sara, Kryukov, Gregory V., Clemons, Paul A., Tsherniak, Aviad, Vazquez, Francisca, Crompton, Brian D., Shamji, Alykhan F., Rodriguez-Galindo, Carlos, Janeway, Katherine A., Roberts, Charles W. M., Stegmaier, Kimberly, van Hummelen, Paul, Cima, Michael J., Langer, Robert S., Garraway, Levi A., Schreiber, Stuart L., Root, David E., Hahn, William C., Boehm, Jesse S.
Publicado 2016