BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease

por Chami, Linda, Checler, Frédéric
Publicado 2012

Ryanodine receptors: Dual contribution to Alzheimer disease?

por Chami, Mounia, Checler, Frédéric
Publicado 2014

Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer’s Disease

por Chami, Mounia, Checler, Frédéric
Publicado 2020

Aminopeptidase A and dipeptidyl peptidase 4: a pathogenic duo in Alzheimer’s disease?

por Checler, Frédéric, Valverde, Audrey
Publicado 2022

The transcription factor X-box binding protein-1 in neurodegenerative diseases

por Dunys, Julie, Duplan, Eric, Checler, Frédéric
Publicado 2014

Parkin as a Molecular Bridge Linking Alzheimer’s and Parkinson’s Diseases?

por Checler, Frédéric, Alves da Costa, Cristine
Publicado 2022

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

por Del Prete, Dolores, Checler, Frédéric, Chami, Mounia
Publicado 2014

The transcription factor XBP-1 in neurodegenerative diseases

por Checler, Frédéric, Duplan, Eric, Alves da Costa, Cristine
Publicado 2013

Aβ42 oligomers modulate β-secretase through an XBP-1s-dependent pathway involving HRD1

por Gerakis, Yannis, Dunys, Julie, Bauer, Charlotte, Checler, Fréderic
Publicado 2016

α-synuclein and p53 functional interplay in physiopathological contexts

por Alves da Costa, Cristine, Duplan, Eric, Checler, Frédéric
Publicado 2016

Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches

por Mary, Arnaud, Eysert, Fanny, Checler, Frédéric, Chami, Mounia
Publicado 2022

Is γ-secretase a beneficial inactivating enzyme of the toxic APP C-terminal fragment C99?

por Checler, Frédéric, Afram, Elissa, Pardossi-Piquard, Raphaëlle, Lauritzen, Inger
Publicado 2021

Direct α-synuclein promoter transactivation by the tumor suppressor p53

por Duplan, Eric, Giordano, Cécile, Checler, Frédéric, Alves da Costa, Cristine
Publicado 2016

The Transcription Factor Function of Parkin: Breaking the Dogma

por Alves da Costa, Cristine, Duplan, Eric, Rouland, Lila, Checler, Frédéric
Publicado 2019

The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson’s Disease Physiopathology

por da Costa, Cristine Alves, Manaa, Wejdane El, Duplan, Eric, Checler, Frédéric
Publicado 2020

Molecular Dysfunctions of Mitochondria-Associated Membranes (MAMs) in Alzheimer’s Disease

por Eysert, Fanny, Kinoshita, Paula Fernanda, Mary, Arnaud, Vaillant-Beuchot, Loan, Checler, Frédéric, Chami, Mounia
Publicado 2020

Targeting γ-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models

por Lauritzen, Inger, Bécot, Anaïs, Bourgeois, Alexandre, Pardossi-Piquard, Raphaëlle, Biferi, Maria-Grazia, Barkats, Martine, Checler, Fréderic
Publicado 2019

Dipeptidyl peptidase 4 contributes to Alzheimer’s disease–like defects in a mouse model and is increased in sporadic Alzheimer’s disease brains

por Valverde, Audrey, Dunys, Julie, Lorivel, Thomas, Debayle, Delphine, Gay, Anne-Sophie, Caillava, Céline, Chami, Mounia, Checler, Frédéric
Publicado 2021

The beta-secretase-derived C-terminal fragment of APP (C99): a key determinant for intraneuronal pathology in the 3xTgAD mouse

por Lauritzen, Inger, Pardossi-Piquard, Raphaelle, Druon, Charlotte, Brigham, Elizabeth, Abraham, Daniel, Ranaldi, Sébatien, Chami, Linda, Dunys, Julie, Checler, Fréderic
Publicado 2013

Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease

por Oulès, Bénédicte, Del Prete, Dolores, Greco, Barbara, Zhang, Xuexin, Lauritzen, Inger, Trebak, Mohamed, Benfenati, Fabio, Checler, Frédéric, Chami, Mounia
Publicado 2013