A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses

por Lin, Xueqiu, Liu, Yanxia, Chemparathy, Augustine, Pande, Tara, La Russa, Marie, Qi, Lei S.
Publicado 2021

Development and Implementation of a Real-time Bundle-adherence Dashboard for Central Line-associated Bloodstream Infections

por Chemparathy, Augustine, Seneviratne, Martin G., Ward, Andrew, Mirchandani, Simran, Li, Ron, Mathew, Roshni, Wood, Matthew, Shin, Andrew Y., Donnelly, Lane F., Scheinker, David, Lee, Grace M.
Publicado 2021

Leveraging nonstructural data to predict structures and affinities of protein–ligand complexes

por Paggi, Joseph M., Belk, Julia A., Hollingsworth, Scott A., Villanueva, Nicolas, Powers, Alexander S., Clark, Mary J., Chemparathy, Augustine G., Tynan, Jonathan E., Lau, Thomas K., Sunahara, Roger K., Dror, Ron O.
Publicado 2021

Multiplexed genome regulation in vivo with hyper-efficient Cas12a

por Guo, Lucie Y., Bian, Jing, Davis, Alexander E., Liu, Pingting, Kempton, Hannah R., Zhang, Xiaowei, Chemparathy, Augustine, Gu, Baokun, Lin, Xueqiu, Rane, Draven A., Jamiolkowski, Ryan M., Hu, Yang, Wang, Sui, Qi, Lei S.
Publicado 2022

Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza

por Abbott, Timothy R., Dhamdhere, Girija, Liu, Yanxia, Lin, Xueqiu, Goudy, Laine, Zeng, Leiping, Chemparathy, Augustine, Chmura, Stephen, Heaton, Nicholas S., Debs, Robert, Pande, Tara, Endy, Drew, La Russa, Marie F., Lewis, David B., Qi, Lei S.
Publicado 2020

A 3’UTR Insertion Is a Candidate Causal Variant at the TMEM106B Locus Associated with Increased Risk for FTLD-TDP

por Chemparathy, Augustine, Guen, Yann Le, Zeng, Yi, Gorzynski, John, Jensen, Tanner, Yang, Chengran, Kasireddy, Nandita, Talozzi, Lia, Belloy, Michael E., Stewart, Ilaria, Gitler, Aaron D., Wagner, Anthony D., Mormino, Elizabeth, Henderson, Victor W., Wyss-Coray, Tony, Ashley, Euan, Cruchaga, Carlos, Greicius, Michael D.
Publicado 2023

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s Disease pathology

por Chemparathy, Augustine, Guen, Yann Le, Chen, Sunny, Lee, Eun-Gyung, Leong, Lesley, Gorzynski, John, Xu, Guangxue, Belloy, Michael, Kasireddy, Nandita, Tauber, Andrés Peña, Williams, Kennedy, Stewart, Ilaria, Wingo, Thomas, Lah, James, Jayadev, Suman, Hales, Chad, Peskind, Elaine, Child, Daniel D, Keene, C Dirk, Cong, Le, Ashley, Euan, Yu, Chang-En, Greicius, Michael D.
Publicado 2023

Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro

por Zeng, Leiping, Liu, Yanxia, Nguyenla, Xammy Huu, Abbott, Timothy R., Han, Mengting, Zhu, Yanyu, Chemparathy, Augustine, Lin, Xueqiu, Chen, Xinyi, Wang, Haifeng, Rane, Draven A., Spatz, Jordan M., Jain, Saket, Rustagi, Arjun, Pinsky, Benjamin, Zepeda, Adrianna E., Kadina, Anastasia P., Walker, John A., Holden, Kevin, Temperton, Nigel, Cochran, Jennifer R., Barron, Annelise E., Connolly, Michael D., Blish, Catherine A., Lewis, David B., Stanley, Sarah A., La Russa, Marie F., Qi, Lei S.
Publicado 2022