Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282

por O’Donnell, John, Tanudra, Angela, Chen, April, Hines, Daniel, Tommasi, Ruben, Mueller, John
Publicado 2020

2526. Ex Vivo Assessment of Sulbactam-Durlobactam (SUL-DUR) Clearance during Continuous Renal Replacement Therapy (CRRT)

por Abouelhassan, Yasmeen, Shen, Yuwei, Chen, April, Ye, Xiaoyi, Nicolau, David P, Kuti, Joseph L
Publicado 2023

Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases

por Durand-Réville, Thomas F., Comita-Prevoir, Janelle, Zhang, Jing, Wu, Xiaoyun, May-Dracka, Tricia L., Romero, Jan Antoinette C., Wu, Frank, Chen, April, Shapiro, Adam B., Carter, Nicole M., McLeod, Sarah M., Giacobbe, Robert A., Verheijen, Jeroen C., Lahiri, Sushmita D., Sacco, Michael D., Chen, Yu, O’Donnell, John P., Miller, Alita A., Mueller, John P., Tommasi, Rubén A.
Publicado 2020