DNA–dependent protein kinase in telomere maintenance and protection

por Sui, Jiangdong, Zhang, Shichuan, Chen, Benjamin P. C.
Publicado 2020

A Sensitive and Quantitative Polymerase Chain Reaction-Based Cell Free In Vitro Non-Homologous End Joining Assay for Hematopoietic Stem Cells

por Shao, Lijian, Feng, Wei, Lee, Kyung-Jong, Chen, Benjamin P. C., Zhou, Daohong
Publicado 2012

Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson–Gilford Progeria Syndrome

por Chiang, Jui-Chung, Chen, Wei-Min, Newman, Ciara, Chen, Benjamin P. C., Lee, Hsinyu
Publicado 2022

DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication

por Sui, Jiangdong, Lin, Yu-Fen, Xu, Kangling, Lee, Kyung-Jong, Wang, Dong, Chen, Benjamin P.C.
Publicado 2015

Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array

por Kuo, Ching-Te, Wang, Jong-Yueh, Lin, Yu-Fen, Wo, Andrew M., Chen, Benjamin P. C., Lee, Hsinyu
Publicado 2017

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry()

por Lee, Kyung-Jong, Shang, Zeng-Fu, Lin, Yu-Fen, Sun, Jingxin, Morotomi-Yano, Keiko, Saha, Debabrata, Chen, Benjamin P.C.
Publicado 2015

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor

por Yu, Lan, Shang, Zeng-Fu, Hsu, Feng-Ming, Zhang, Zhang, Tumati, Vasu, Lin, Yu-Fen, Chen, Benjamin P.C., Saha, Debabrata
Publicado 2015

Transcriptional elongation requires DNA break-induced signalling

por Bunch, Heeyoun, Lawney, Brian P., Lin, Yu-Fen, Asaithamby, Aroumougame, Murshid, Ayesha, Wang, Yaoyu E., Chen, Benjamin P. C., Calderwood, Stuart K.
Publicado 2015

PIDD mediates the association of DNA-PKcs and ATR at stalled replication forks to facilitate the ATR signaling pathway

por Lin, Yu-Fen, Shih, Hung-Ying, Shang, Zeng-Fu, Kuo, Ching-Te, Guo, Jiaming, Du, Chunying, Lee, Hsinyu, Chen, Benjamin P C
Publicado 2018

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments

por Yu, Lan, Shang, Zeng-Fu, Abdisalaam, Salim, Lee, Kyung-Jong, Gupta, Arun, Hsieh, Jer-Tsong, Asaithamby, Aroumougame, Chen, Benjamin P.C., Saha, Debabrata
Publicado 2016

ATM phosphorylates the FATC domain of DNA-PK(cs) at threonine 4102 to promote non-homologous end joining

por Lu, Huiming, Zhang, Qin, Laverty, Daniel J, Puncheon, Andrew C, Augustine, Mathew M, Williams, Gareth J, Nagel, Zachary D, Chen, Benjamin P C, Davis, Anthony J
Publicado 2023

Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitot...

por Yu, Lan, Lang, Yue, Hsu, Ching-Cheng, Chen, Wei-Min, Chiang, Jui-Chung, Hsieh, Jer-Tsong, Story, Michael D., Shang, Zeng-Fu, Chen, Benjamin P. C., Saha, Debabrata
Publicado 2021

Autophosphorylation of DNA-PK(CS) regulates its dynamics at DNA double-strand breaks

por Uematsu, Naoya, Weterings, Eric, Yano, Ken-ichi, Morotomi-Yano, Keiko, Jakob, Burkhard, Taucher-Scholz, Gisela, Mari, Pierre-Olivier, van Gent, Dik C., Chen, Benjamin P.C., Chen, David J.
Publicado 2007

A nanodroplet cell processing platform facilitating drug synergy evaluations for anti-cancer treatments

por Kuo, Ching-Te, Wang, Jong-Yueh, Lu, Siang-Rong, Lai, Yu-Sheng, Chang, Hsiu-Hao, Hsieh, Jer-Tsong, Wo, Andrew M., Chen, Benjamin P. C., Lu, Jen-Her, Lee, Hsinyu
Publicado 2019

BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ

por Bunch, Heeyoun, Jeong, Jaehyeon, Kang, Keunsoo, Jo, Doo Sin, Cong, Anh T. Q., Kim, Deukyeong, Kim, Donguk, Cho, Dong-Hyung, Lee, You Mie, Chen, Benjamin P. C., Schellenberg, Matthew J., Calderwood, Stuart K.
Publicado 2021

Differential Radiosensitivity Phenotypes of DNA-PKcs Mutations Affecting NHEJ and HRR Systems following Irradiation with Gamma-Rays or Very Low Fluences of Alpha Particles

por Lin, Yu-Fen, Nagasawa, Hatsumi, Little, John B., Kato, Takamitsu A., Shih, Hung-Ying, Xie, Xian-Jin, Wilson Jr., Paul F., Brogan, John R., Kurimasa, Akihiro, Chen, David J., Bedford, Joel S., Chen, Benjamin P. C.
Publicado 2014

Lysophosphatidic acid receptor LPA(3) prevents oxidative stress and cellular senescence in Hutchinson–Gilford progeria syndrome

por Chen, Wei‐Min, Chiang, Jui‐Chung, Lin, Yueh‐Chien, Lin, Yu‐Nung, Chuang, Pei‐Yun, Chang, Ya‐Chi, Chen, Chien‐Chin, Wu, Kao‐Yi, Hsieh, Jung‐Chien, Chen, Shih‐Kuo, Huang, Wei‐Pang, Chen, Benjamin P. C., Lee, Hsinyu
Publicado 2019

Whole-Body (12)C Irradiation Transiently Decreases Mouse Hippocampal Dentate Gyrus Proliferation and Immature Neuron Number, but Does Not Change New Neuron Survival Rate

por Zanni, Giulia, Deutsch, Hannah M., Rivera, Phillip D., Shih, Hung-Ying, LeBlanc, Junie A., Amaral, Wellington Z., Lucero, Melanie J., Redfield, Rachel L., DeSalle, Matthew J., Chen, Benjamin P. C., Whoolery, Cody W., Reynolds, Ryan P., Yun, Sanghee, Eisch, Amelia J.
Publicado 2018

Multi-domain cognitive assessment of male mice shows space radiation is not harmful to high-level cognition and actually improves pattern separation

por Whoolery, Cody W., Yun, Sanghee, Reynolds, Ryan P., Lucero, Melanie J., Soler, Ivan, Tran, Fionya H., Ito, Naoki, Redfield, Rachel L., Richardson, Devon R., Shih, Hung-ying, Rivera, Phillip D., Chen, Benjamin P. C., Birnbaum, Shari G., Stowe, Ann M., Eisch, Amelia J.
Publicado 2020

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

por Zhang, Shichuan, Yajima, Hirohiko, Huynh, HoangDinh, Zheng, Junke, Callen, Elsa, Chen, Hua-Tang, Wong, Nancy, Bunting, Samuel, Lin, Yu-Fen, Li, Mengxia, Lee, Kyung-Jone, Story, Michael, Gapud, Eric, Sleckman, Barry P., Nussenzweig, André, Zhang, Cheng Cheng, Chen, David J., Chen, Benjamin P.C.
Publicado 2011