DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response

por Lin, Yu-Fen, Shih, Hung-Ying, Shang, Zengfu, Matsunaga, Shinji, Chen, Benjamin PC
Publicado 2014

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

por Olsen, Birgitte B, Wang, Shih-Ya, Svenstrup, Tina H, Chen, Benjamin PC, Guerra, Barbara
Publicado 2012

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1

por Sui, Jiangdong, Li, Mengxia, Qian, Chengyuan, Wang, Shufeng, Cheng, Yi, Chen, Benjamin PC, Wang, Dong
Publicado 2014

DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication

por Sui, Jiangdong, Lin, Yu-Fen, Xu, Kangling, Lee, Kyung-Jong, Wang, Dong, Chen, Benjamin P.C.
Publicado 2015

The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry()

por Lee, Kyung-Jong, Shang, Zeng-Fu, Lin, Yu-Fen, Sun, Jingxin, Morotomi-Yano, Keiko, Saha, Debabrata, Chen, Benjamin P.C.
Publicado 2015

NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor

por Yu, Lan, Shang, Zeng-Fu, Hsu, Feng-Ming, Zhang, Zhang, Tumati, Vasu, Lin, Yu-Fen, Chen, Benjamin P.C., Saha, Debabrata
Publicado 2015

DNA‐PKcs and ATM modulate mitochondrial ADP‐ATP exchange as an oxidative stress checkpoint mechanism

por Chen, Wei‐Min, Chiang, Jui‐Chung, Shang, Zengfu, Palchik, Guillermo, Newman, Ciara, Zhang, Yuanyuan, Davis, Anthony J, Lee, Hsinyu, Chen, Benjamin PC
Publicado 2023

Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments

por Yu, Lan, Shang, Zeng-Fu, Abdisalaam, Salim, Lee, Kyung-Jong, Gupta, Arun, Hsieh, Jer-Tsong, Asaithamby, Aroumougame, Chen, Benjamin P.C., Saha, Debabrata
Publicado 2016

Autophosphorylation of DNA-PK(CS) regulates its dynamics at DNA double-strand breaks

por Uematsu, Naoya, Weterings, Eric, Yano, Ken-ichi, Morotomi-Yano, Keiko, Jakob, Burkhard, Taucher-Scholz, Gisela, Mari, Pierre-Olivier, van Gent, Dik C., Chen, Benjamin P.C., Chen, David J.
Publicado 2007

Spontaneous Tumor Development in Bone Marrow Rescued DNA-PKcs(3A/3A) Mice Due to Dysfunction of Telomere Leading Strand Deprotection

por Zhang, Shichuan, Matsunaga, Shinji, Lin, Yu-Fen, Sishc, Brock, Shang, Zengfu, Sui, Jiangdong, Shih, Hung-Ying, Zhao, Yong, Foreman, Oded, Story, Michael D., Chen, David J., Chen, Benjamin PC.
Publicado 2015

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

por Zhang, Shichuan, Yajima, Hirohiko, Huynh, HoangDinh, Zheng, Junke, Callen, Elsa, Chen, Hua-Tang, Wong, Nancy, Bunting, Samuel, Lin, Yu-Fen, Li, Mengxia, Lee, Kyung-Jone, Story, Michael, Gapud, Eric, Sleckman, Barry P., Nussenzweig, André, Zhang, Cheng Cheng, Chen, David J., Chen, Benjamin P.C.
Publicado 2011

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress

por Yang, Yeran, Liu, Zhenbo, Wang, Fengli, Temviriyanukul, Piya, Ma, Xiaolu, Tu, Yingfeng, Lv, Lingna, Lin, Yu-Fen, Huang, Min, Zhang, Ting, Pei, Huadong, Chen, Benjamin P.C., Jansen, Jacob G., de Wind, Niels, Fischhaber, Paula L., Friedberg, Errol C., Tang, Tie-Shan, Guo, Caixia
Publicado 2015

Targeting radioresistance and replication fork stability in prostate cancer

por Li, Xiangyi, Baek, GuemHee, Carreira, Suzanne, Yuan, Wei, Ma, Shihong, Hofstad, Mia, Lee, Sora, Gao, Yunpeng, Bertan, Claudia, Fenor de la Maza, Maria de los Dolores, Alluri, Prasanna G., Burma, Sandeep, Chen, Benjamin P.C., Raj, Ganesh V., de Bono, Johann, Pommier, Yves, Mani, Ram S.
Publicado 2022

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

por Kim, Jiyeon, Hu, Zeping, Cai, Ling, Li, Kailong, Choi, Eunhee, Faubert, Brandon, Bezwada, Divya, Rodriguez-Canales, Jaime, Villalobos, Pamela, Lin, Yu-Fen, Ni, Min, Huffman, Kenneth E., Girard, Luc, Byers, Lauren A., Unsal-Kacmaz, Keziban, Peña, Christopher G., Heymach, John V., Wauters, Els, Vansteenkiste, Johan, Castrillon, Diego H., Chen, Benjamin P.C., Wistuba, Ignacio, Lambrechts, Diether, Xu, Jian, Minna, John D., DeBerardinis, Ralph J.
Publicado 2017