F-box protein substrate recognition: A new insight

por Chen, Bill B., Mallampalli, Rama K.
Publicado 2013

Natural Products as Targeted Modulators of the Immune System

por Wang, Kai, Conlon, Michael, Ren, Wenkai, Chen, Bill B., Bączek, Tomasz
Publicado 2018

F box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest

por Chen, Bill B., Glasser, Jennifer R., Coon, Tiffany A., Mallampalli, Rama K.
Publicado 2011

Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal

por Agassandian, Marianna, Chen, Bill B., Pulijala, Roopa, Kaercher, Leah, Glasser, Jennifer R., Mallampalli, Rama K.
Publicado 2012

Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

por Coon, Tiffany A., McKelvey, Alison C., Weathington, Nate M., Birru, Rahel L., Lear, Travis, Leikauf, George D., Chen, Bill B.
Publicado 2014

A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis

por Chen, Yanwen, Evankovich, John W., Lear, Travis B., Tuncer, Ferhan, Kennerdell, Jason R., Camarco, Daniel P., Shishido, Morgan S., Liu, Yuan, Chen, Bill B.
Publicado 2020

Discovery of bactericides as an acute mitochondrial membrane damage inducer

por Houston, Ryan, Sekine, Yusuke, Larsen, Mads B, Murakami, Kei, Mullett, Steven J., Wendell, Stacy G., Narendra, Derek P., Chen, Bill B., Sekine, Shiori
Publicado 2021

Targeting the deubiquitinase STAMBP inhibits NALP7 inflammasome activity

por Bednash, Joseph S., Weathington, Nathaniel, Londino, James, Rojas, Mauricio, Gulick, Dexter L., Fort, Robert, Han, SeungHye, McKelvey, Alison C., Chen, Bill B., Mallampalli, Rama K.
Publicado 2017

A Repurposed Drug Screen for Compounds Regulating Aquaporin 5 Stability in Lung Epithelial Cells

por Villandre, John, White, Virginia, Lear, Travis B., Chen, Yanwen, Tuncer, Ferhan, Vaiz, Emily, Tuncer, Beyza, Lockwood, Karina, Camarco, Dan, Liu, Yuan, Chen, Bill B., Evankovich, John
Publicado 2022

E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro

por Lear, Travis B., Boudreau, Áine N., Lockwood, Karina C., Chu, Elise, Camarco, Daniel P., Cao, Qing, Nguyen, Matthew, Evankovich, John W., Finkel, Toren, Liu, Yuan, Chen, Bill B.
Publicado 2023

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity

por McKelvey, Alison C, Lear, Travis B, Dunn, Sarah R, Evankovich, John, Londino, James D, Bednash, Joseph S, Zhang, Yingze, McVerry, Bryan J, Liu, Yuan, Chen, Bill B
Publicado 2016

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

por Chen, Bill B., Coon, Tiffany A., Glasser, Jennifer R., McVerry, Bryan J., Zhao, Jing, Zhao, Yutong, Zou, Chunbin, Ellis, Bryon, Sciurba, Frank C., Zhang, Yingze, Mallampalli, Rama K.
Publicado 2013

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4

por Lear, Travis, McKelvey, Alison C., Rajbhandari, Shristi, Dunn, Sarah R., Coon, Tiffany A., Connelly, William, Zhao, Joe Y., Kass, Daniel J., Zhang, Yingze, Liu, Yuan, Chen, Bill B.
Publicado 2016

The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia

por Chakraborty, Krishnendu, Raundhal, Mahesh, Chen, Bill B., Morse, Christina, Tyurina, Yulia Y., Khare, Anupriya, Oriss, Timothy B., Huff, Rachael, Lee, Janet S., St. Croix, Claudette M., Watkins, Simon, Mallampalli, Rama K., Kagan, Valerian E., Ray, Anuradha, Ray, Prabir
Publicado 2017

Modulation of lysosomal function as a therapeutic approach for coronaviral infections

por Liu, Yuan, Lear, Travis, Larsen, Mads, Lin, Bo, Cao, Qing, Alfaras, Irene, Kennerdell, Jason, Salminen, Laura, Camarco, Daniel, Lockwood, Karina, Ma, Jing, Liu, Jie, Tan, Jay, Myerburg, Michael, Chen, Yanwen, St Croix, Claudette, Sekine, Yusuke, Evankovich, John, Finkel, Toren, Chen, Bill
Publicado 2021

Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection

por Zhao, Yani, Olonisakin, Tolani F., Xiong, Zeyu, Hulver, Mei, Sayeed, Sameera, Yu, Min Ting, Gregory, Alyssa D., Kochman, Elizabeth J., Chen, Bill B., Mallampalli, Rama K., Sun, Ming, Silverstein, Roy L., Stolz, Donna B., Shapiro, Steve D., Ray, Anuradha, Ray, Prabir, Lee, Janet S.
Publicado 2014

Glycemic control and adherence to basal insulin therapy in Taiwanese patients with type 2 diabetes mellitus

por Chien, Ming‐Nan, Chen, Yen‐Ling, Hung, Yi‐Jen, Wang, Shu‐Yi, Lu, Wen‐Tsung, Chen, Chih‐Hung, Lin, Ching‐Ling, Huang, Tze‐Pao, Tsai, Ming‐Han, Tseng, Wei‐Kung, Wu, Ta‐Jen, Ho, Cheng, Lin, Wen‐Yu, Chen, Bill, Chuang, Lee‐Ming
Publicado 2016

A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry

por Chen, Yanwen, Lear, Travis B., Evankovich, John W., Larsen, Mads B., Lin, Bo, Alfaras, Irene, Kennerdell, Jason R., Salminen, Laura, Camarco, Daniel P., Lockwood, Karina C., Liu, Jie, Myerburg, Michael M., McDyer, John F., Liu, Yuan, Finkel, Toren, Chen, Bill B.
Publicado 2020

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance

por Liu, Yuan, Jurczak, Michael J., Lear, Travis B., Lin, Bo, Larsen, Mads B., Kennerdell, Jason R., Chen, Yanwen, Huckestein, Brydie R., Nguyen, Matthew K., Tuncer, Ferhan, Jiang, Yu, Monga, Satdarshan P., O’Donnell, Christopher P., Finkel, Toren, Chen, Bill B., Mallampalli, Rama K.
Publicado 2021

A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry

por Chen, Yanwen, Lear, Travis B., Evankovich, John W., Larsen, Mads B., Lin, Bo, Alfaras, Irene, Kennerdell, Jason R., Salminen, Laura, Camarco, Daniel P., Lockwood, Karina C., Tuncer, Ferhan, Liu, Jie, Myerburg, Michael M., McDyer, John F., Liu, Yuan, Finkel, Toren, Chen, Bill B.
Publicado 2021