High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation

por Al-Aghbar, Mohammad Ameen, Chu, Yeh-Shiu, Chen, Bing-Mae, Roffler, Steve R.
Publicado 2018

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

por Hsieh, Yuan-Ting, Lin, Hsuan-Pei, Chen, Bing-Mae, Huang, Ping-Ting, Roffler, Steve R.
Publicado 2015

Anti-PEG antibodies before and after a first dose of Comirnaty® (mRNA-LNP-based SARS-CoV-2 vaccine)

por Bavli, Yaelle, Chen, Bing-Mae, Gross, Guy, Hershko, Alon, Turjeman, Keren, Roffler, Steve, Barenholz, Yechezkel
Publicado 2023

Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines

por Chen, Wei-An, Chang, Deng-Yuan, Chen, Bing-Mae, Lin, Yi-Chen, Barenholz, Yechezekel, Roffler, Steve R.
Publicado 2023

Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

por Su, Yu-Cheng, Burnouf, Pierre-Alain, Chuang, Kuo-Hsiang, Chen, Bing-Mae, Cheng, Tian-Lu, Roffler, Steve R.
Publicado 2017

PEGylated Liposomal Methyl Prednisolone Succinate does not Induce Infusion Reactions in Patients: A Correlation Between in Vitro Immunological and in Vivo Clinical Studies

por Bavli, Yaelle, Chen, Bing-Mae, Roffler, Steve R., Dobrovolskaia, Marina A., Elnekave, Eldad, Ash, Shifra, Barenholz, Yechezkel, Turjeman, Keren
Publicado 2020

Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies

por Su, Yu-Cheng, Al-Qaisi, Talal S, Tung, Hsin-Yi, Cheng, Tian-Lu, Chuang, Kuo-Hsiang, Chen, Bing-Mae, Roffler, Steve R
Publicado 2014

Both IgM and IgG Antibodies against Polyethylene Glycol Can Alter the Biological Activity of Methoxy Polyethylene Glycol-Epoetin Beta in Mice

por Chang, Tien-Ching, Chen, Bing-Mae, Lin, Wen-Wei, Yu, Pei-Hua, Chiu, Yi-Wen, Chen, Yuan-Tsong, Wu, Jer-Yuarn, Cheng, Tian-Lu, Hwang, Daw-Yang, Roffler, Steve
Publicado 2019

The B7-1 Cytoplasmic Tail Enhances Intracellular Transport and Mammalian Cell Surface Display of Chimeric Proteins in the Absence of a Linear ER Export Motif

por Lin, Yi-Chieh, Chen, Bing-Mae, Lu, Wei-Cheng, Su, Chien-I, Prijovich, Zeljko M., Chung, Wen-Chuan, Wu, Pei-Yu, Chen, Kai-Chuan, Lee, I-Chiao, Juan, Ting-Yi, Roffler, Steve R.
Publicado 2013

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

por Chang, Chia-Jung, Chen, Chien-Hsiun, Chen, Bing-Mae, Su, Yu-Cheng, Chen, Ying-Ting, Hershfield, Michael S., Lee, Ming-Ta Michael, Cheng, Tian-Lu, Chen, Yuan-Tsong, Roffler, Steve R., Wu, Jer-Yuarn
Publicado 2017

High-Throughput Sorting of the Highest Producing Cell via a Transiently Protein-Anchored System

por Chuang, Kuo-Hsiang, Hsieh, Yuan-Chin, Chiang, I-Shiuan, Chuang, Chih-Hung, Kao, Chien-Han, Cheng, Ta-Chun, Wang, Yeng-Tseng, Lin, Wen-Wei, Chen, Bing-Mae, Roffler, Steve R., Huang, Ming-Yii, Cheng, Tian-Lu
Publicado 2014

The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering

por Chen, Bing-Mae, Al-Aghbar, Mohammad Ameen, Lee, Chien-Hsin, Chang, Tien-Ching, Su, Yu-Cheng, Li, Ya-Chen, Chang, Shih-En, Chen, Chin-Chuan, Chung, Tsai-Hua, Liao, Yuan-Chun, Lee, Chau-Hwang, Roffler, Steve R.
Publicado 2017

Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

por Hsieh, Yuan-Chin, Wang, Hsin-Ell, Lin, Wen-Wei, Roffler, Steve R., Cheng, Ta-Chun, Su, Yu-Cheng, Li, Jia-Je, Chen, Chao-Cheng, Huang, Chun-Han, Chen, Bing-Mae, Wang, Jaw-Yuan, Cheng, Tian-Lu, Chen, Fang-Ming
Publicado 2018

Entropy-driven binding of gut bacterial β-glucuronidase inhibitors ameliorates irinotecan-induced toxicity

por Lin, Hsien-Ya, Chen, Chia-Yu, Lin, Ting-Chien, Yeh, Lun-Fu, Hsieh, Wei-Che, Gao, Shijay, Burnouf, Pierre-Alain, Chen, Bing-Mae, Hsieh, Tung-Ju, Dashnyam, Punsaldulam, Kuo, Yen-Hsi, Tu, Zhijay, Roffler, Steve R., Lin, Chun-Hung
Publicado 2021