The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased immunotherapy response in pan-cancer

por Luo, Jiangti, Chen, Canping, Liu, Zhixian, Wang, Xiaosheng
Publicado 2023

Pan-Cancer Analysis Reveals That E1A Binding Protein p300 Mutations Increase Genome Instability and Antitumor Immunity

por Chen, Zuobing, Chen, Canping, Li, Lin, Zhang, Tianfang, Wang, Xiaosheng
Publicado 2021

The spliceosome pathway activity correlates with reduced anti-tumor immunity and immunotherapy response, and unfavorable clinical outcomes in pan-cancer

por Chen, Zuobing, Chen, Canping, Li, Lin, Zhang, Tianfang, Wang, Xiaosheng
Publicado 2021

KALRN mutations promote antitumor immunity and immunotherapy response in cancer

por Li, Mengyuan, Ma, Yuxiang, Zhong, You, Liu, Qian, Chen, Canping, Qiang, Lei, Wang, Xiaosheng
Publicado 2020

Identifying novel factors associated with COVID-19 transmission and fatality using the machine learning approach

por Li, Mengyuan, Zhang, Zhilan, Cao, Wenxiu, Liu, Yijing, Du, Beibei, Chen, Canping, Liu, Qian, Uddin, Md. Nazim, Jiang, Shanmei, Chen, Cai, Zhang, Yue, Wang, Xiaosheng
Publicado 2021

Supervised learning of high-confidence phenotypic subpopulations from single-cell data

por Ren, Tao, Chen, Canping, Danilov, Alexey V., Liu, Susan, Guan, Xiangnan, Du, Shunyi, Wu, Xiwei, Sherman, Mara H., Spellman, Paul T., Coussens, Lisa M., Adey, Andrew C., Mills, Gordon B., Wu, Ling-Yun, Xia, Zheng
Publicado 2023

Pharmacologic targeting of Nedd8-activating enzyme reinvigorates T-cell responses in lymphoid neoplasia

por Wang, Xiaoguang, Chen, Canping, Vuong, Dan, Rodriguez-Rodriguez, Sonia, Lam, Vi, Roleder, Carly, Wang, Jing H., Kambhampati, Swetha, Berger, Allison, Pennock, Nathan, Torka, Pallawi, Hernandez-Ilizaliturri, Francisco, Siddiqi, Tanya, Wang, Lili, Xia, Zheng, Danilov, Alexey V.
Publicado 2023

Pevonedistat, a Nedd8-activating enzyme inhibitor, in combination with ibrutinib in patients with relapsed/refractory B-cell non-Hodgkin lymphoma

por Torka, Pallawi, Kambhampati, Swetha, Chen, Lu, Wang, Xiaoguang, Chen, Canping, Vuong, Dan, Qin, Hanjun, Muir, Alexandra, Orand, Kirsten, Borja, Ivana, Lynne Smith, D., Herrera, Alex F., Spurgeon, Stephen E. F., Park, Byung, Lewis, Lionel D., Hernandez-Ilizaliturri, Francisco, Xia, Zheng, Danilov, Alexey V.
Publicado 2023