Optimism Bias in the Design of Phase III Randomized Control Trials Evaluating PD-1/PD-L1 Targeting Monoclonal Antibodies

por Al-Showbaki, Laith, Almugbel, Fahad A, Alqaisi, Husam A, Amir, Eitan, Chen, Eric X
Publicado 2022

Barriers in phase I cancer clinical trials referrals and enrollment: five-year experience at the Princess Margaret Hospital

por Ho, Jeremy, Pond, Gregory R, Newman, Colin, Maclean, Martha, Chen, Eric X, Oza, Amit M, Siu, Lillian L
Publicado 2006

Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

por Chau, Nicole G, Florescu, Ana, Chan, Kelvin K, Wang, Lisa, Chen, Eric X, Bedard, Philippe, Oza, Amit M, Siu, Lillian L
Publicado 2011

Semen and serum platinum levels in cisplatin‐treated survivors of germ cell cancer

por Malone, Eoghan R., Lewin, Jeremy, Li, Xuan, Zhang, Wen‐Jiang, Lau, Susan, Jarvi, Keith, Hamilton, Robert J., Hansen, Aaron R., Chen, Eric X., Bedard, Philippe L.
Publicado 2021

The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of...

por Chau, Nicole G, Perez-Ordonez, Bayardo, Zhang, Katherine, Pham, Nhu-An, Ho, James, Zhang, Tong, Ludkovski, Olga, Wang, Lisa, Chen, Eric X, Tsao, Ming-Sound, Kamel-Reid, Suzanne, Siu, Lillian L
Publicado 2011

Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti–Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer

por Topham, James T., O'Callaghan, Chris J., Feilotter, Harriet, Kennecke, Hagen F., Lee, Young S., Li, Weimin, Banks, Kimberly C., Quinn, Katie, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, Chen, Eric X., Loree, Jonathan M.
Publicado 2023

Impact of Sites of Metastatic Dissemination on Survival in Advanced Gastroesophageal Adenocarcinoma

por Wang, Xin, Espin-Garcia, Osvaldo, Jiang, Di Maria, Allen, Michael J., Ma, Lucy X., Bach, Yvonne, Chen, Eric X., Darling, Gail, Yeung, Johnathan C., Wong, Rebecca K.S., Veit-Haibach, Patrick, Kalimuthu, Sangeetha, Jang, Raymond W., Elimova, Elena
Publicado 2022

An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

por Longo, Joseph, Mullen, Peter J., Yu, Rosemary, van Leeuwen, Jenna E., Masoomian, Mehdi, Woon, Dixon T.S., Wang, Yuzhuo, Chen, Eric X., Hamilton, Robert J., Sweet, Joan M., van der Kwast, Theodorus H., Fleshner, Neil E., Penn, Linda Z.
Publicado 2019

A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer

por Longo, Joseph, Hamilton, Robert J., Masoomian, Mehdi, Khurram, Najia, Branchard, Emily, Mullen, Peter J., Elbaz, Mohamad, Hersey, Karen, Chadwick, Dianne, Ghai, Sangeet, Andrews, David W., Chen, Eric X., van der Kwast, Theodorus H., Fleshner, Neil E., Penn, Linda Z.
Publicado 2020

Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma

por Bruce, Jeff P., Hui, Angela B. Y., Shi, Wei, Perez-Ordonez, Bayardo, Weinreb, Ilan, Xu, Wei, Haibe-Kains, Benjamin, Waggott, Daryl M., Boutros, Paul C., O'Sullivan, Brian, Waldron, John, Huang, Shao Hui, Chen, Eric X., Gilbert, Ralph, Liu, Fei-Fei
Publicado 2015

The ongoing challenge of large anal cancers: prospective long term outcomes of intensity-modulated radiation therapy with concurrent chemotherapy

por Hosni, Ali, Han, Kathy, Le, Lisa W., Ringash, Jolie, Brierley, James, Wong, Rebecca, Dinniwell, Robert, Brade, Anthony, Dawson, Laura A., Cummings, Bernard J., Krzyzanowska, Monika K., Chen, Eric X., Hedley, David, Knox, Jennifer, Easson, Alexandra M., Lindsay, Patricia, Craig, Tim, Kim, John
Publicado 2018

Comparison of Four Clinical Prognostic Scores in Patients with Advanced Gastric and Esophageal Cancer

por Ma, Lucy X, Espin-Garcia, Osvaldo, Bach, Yvonne, Aoyama, Hiroko, Allen, Michael J, Wang, Xin, Darling, Gail E, Yeung, Jonathan, Swallow, Carol J, Brar, Savtaj, Veit-Haibach, Patrick, Kalimuthu, Sangeetha, Wong, Rebecca, Chen, Eric X, O’Kane, Grainne M, Jang, Raymond W, Elimova, Elena
Publicado 2022

Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer

por Boutin, Mélina, Topham, James T., Feilotter, Harriet, Kennecke, Hagen F., Couture, Félix, Harb, Mohammed, Kavan, Peter, Berry, Scott, Lim, Howard J., Goffin, John R., Ahmad, Chaudhary, Lott, Anthony, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, O’Callaghan, Chris J., Chen, Eric X., Loree, Jonathan M.
Publicado 2023

A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors

por Diaz-Padilla, Ivan, Hirte, Hal, Oza, Amit M., Clarke, Blaise A., Cohen, Brenda, Reedjik, Michael, Zhang, Tong, Kamel-Reid, Suzanne, Ivy, S. Percy, Hotte, Sebastien J., Razak, Albiruni A. R., Chen, Eric X., Brana, Irene, Wizemann, Monika, Wang, Lisa, Siu, Lillian L., Bedard, Philippe L.
Publicado 2013

Surveillance and outcomes after curative resection for gastroesophageal adenocarcinoma

por Jiang, Di M., Suzuki, Chihiro, Espin‐Garcia, Osvaldo, Lim, Charles H., Ma, Lucy X., Sun, Peiran, Sim, Hao‐Wen, Natori, Akina, Chan, Bryan A., Moignard, Stephanie, Chen, Eric X., Liu, Geoffrey, Swallow, Carol J., Darling, Gail E., Wong, Rebecca, Jang, Raymond W., Elimova, Elena
Publicado 2020

Combination of clinical, radiomic, and “delta” radiomic features in survival prediction of metastatic gastroesophageal adenocarcinoma

por Krishna, Satheesh, Sertic, Andrew, Liu, Zhihui (Amy), Liu, Zijin, Darling, Gail E., Yeung, Jonathon, Wong, Rebecca, Chen, Eric X., Kalimuthu, Sangeetha, Allen, Michael J., Suzuki, Chihiro, Panov, Elan, Ma, Lucy X., Bach, Yvonne, Jang, Raymond W., Swallow, Carol J., Brar, Savtaj, Elimova, Elena, Veit-Haibach, Patrick
Publicado 2023

Prognostic significance of nutritional markers in metastatic gastric and esophageal adenocarcinoma

por Ma, Lucy X., Taylor, Kirsty, Espin‐Garcia, Osvaldo, Anconina, Reut, Suzuki, Chihiro, Allen, Michael J., Honorio, Marta, Bach, Yvonne, Allison, Frances, Chen, Eric X., Brar, Savtaj, Swallow, Carol J., Yeung, Jonathan, Darling, Gail E., Wong, Rebecca, Kalimuthu, Sangeetha N., Jang, Raymond W., Veit‐Haibach, Patrick, Elimova, Elena
Publicado 2020

Latency and interval therapy affect the evolution in metastatic colorectal cancer

por Nikbakht, Hamid, Jessa, Selin, Sukhai, Mahadeo A., Arseneault, Madeleine, Zhang, Tong, Letourneau, Louis, Thomas, Mariam, Bourgey, Mathieu, Roehrl, Michael H. A., Eveleigh, Robert, Chen, Eric X., Krzyzanowska, Monika, Moore, Malcolm J., Giesler, Amanda, Yu, Celeste, Bedard, Philippe L., Kamel-Reid, Suzanne, Majewski, Jacek, Siu, Lillian L., Riazalhosseini, Yasser, Graham, Donna M.
Publicado 2020

Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction

por Voon, Pei Jye, Chen, Eric X., Chen, Helen X., Lockhart, Albert C., Sahebjam, Solmaz, Kelly, Karen, Vaishampayan, Ulka N., Subbiah, Vivek, Razak, Albiruni R., Renouf, Daniel J., Hotte, Sebastien J., Singh, Arti, Bedard, Philippe L., Hansen, Aaron R., Ivy, S. Percy, Wang, Lisa, Stayner, Lee-Anne, Siu, Lillian L., Spreafico, Anna
Publicado 2022

Effect of Combined Immune Checkpoint Inhibition vs Best Supportive Care Alone in Patients With Advanced Colorectal Cancer: The Canadian Cancer Trials Group CO.26 Study

por Chen, Eric X., Jonker, Derek J., Loree, Jonathan M., Kennecke, Hagen F., Berry, Scott R., Couture, Felix, Ahmad, Chaudhary E., Goffin, John R., Kavan, Petr, Harb, Mohammed, Colwell, Bruce, Samimi, Setareh, Samson, Benoit, Abbas, Tahir, Aucoin, Nathalie, Aubin, Francine, Koski, Sheryl L., Wei, Alice C., Magoski, Nadine M., Tu, Dongsheng, O’Callaghan, Chris J.
Publicado 2020