Targeting human MutT homolog 1 (MTH1) for cancer eradication: current progress and perspectives

por Yin, Yizhen, Chen, Fener
Publicado 2020

Structural-Based Optimizations of the Marine-Originated Meridianin C as Glucose Uptake Agents by Inhibiting GSK-3β

por Han, Shuwen, Zhuang, Chunlin, Zhou, Wei, Chen, Fener
Publicado 2021

Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years

por Zhuang, Chunlin, Pannecouque, Christophe, De Clercq, Erik, Chen, Fener
Publicado 2020

Novel amide-functionalized chloramphenicol base bifunctional organocatalysts for enantioselective alcoholysis of meso-cyclic anhydrides

por Xu, Lingjun, Han, Shuwen, Yan, Linjie, Wang, Haifeng, Peng, Haihui, Chen, Fener
Publicado 2018

Improving the positional adaptability: structure-based design of biphenyl-substituted diaryltriazines as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

por Jin, Kaijun, Liu, Minjie, Zhuang, Chunlin, De Clercq, Erik, Pannecouque, Christophe, Meng, Ge, Chen, Fener
Publicado 2020

Chiral Syn-1,3-diol Derivatives via a One-Pot Diastereoselective Carboxylation/ Bromocyclization of Homoallylic Alcohols

por Huang, Guanxin, Liu, Minjie, Xiong, Fangjun, Meng, Ge, Tao, Yuan, Wu, Yan, Peng, Haihui, Chen, Fener
Publicado 2018

A unified strategy to prostaglandins: chemoenzymatic total synthesis of cloprostenol, bimatoprost, PGF(2α), fluprostenol, and travoprost guided by biocatalytic retrosynthesis

por Zhu, Kejie, Jiang, Meifen, Ye, Baijun, Zhang, Guo-Tai, Li, Weijian, Tang, Pei, Huang, Zedu, Chen, Fener
Publicado 2021

Additive-controlled asymmetric iodocyclization enables enantioselective access to both α- and β-nucleosides

por Wang, Qi, Mu, Jiayi, Zeng, Jie, Wan, Linxi, Zhong, Yangyang, Li, Qiuhong, Li, Yitong, Wang, Huijing, Chen, Fener
Publicado 2023

Development of fluorine-substituted NH(2)-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors: Boosting the safety and metabolic stability

por Jin, Xin, Wang, Shuai, Zhao, Limin, Huang, Wenjuan, Zhang, Yinxiang, Pannecouque, Christophe, De Clercq, Erik, Meng, Ge, Piao, Huri, Chen, Fener
Publicado 2023

Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance

por Xiao, You-Cai, Chen, Xiao-Pan, Deng, Ji, Yan, Yu-Hang, Zhu, Kai-Rong, Li, Gen, Yu, Jun-Lin, Brem, Jürgen, Chen, Fener, Schofield, Christopher J., Li, Guo-Bo
Publicado 2021

Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

por Guo, Hong-Yan, Xing, Yue, Sun, Yu-Qiao, Liu, Can, Xu, Qian, Shang, Fan-Fan, Zhang, Run-Hui, Jin, Xue-Jun, Chen, Fener, Lee, Jung Joon, Kang, Dongzhou, Shen, Qing-Kun, Quan, Zhe-Shan
Publicado 2022