Development of heart failure with preserved ejection fraction is independent of eosinophils in a preclinical model

por Pan, Qi, Chen, Cheng, Gong, Zhaoting, Chen, Guihao, Yang, Yuejin
Publicado 2023

Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathwa...

por Qi, Kang, Yang, Yuejin, Geng, Yongjian, Cui, Hehe, Li, Xiangdong, Jin, Chen, Chen, Guihao, Tian, Xiaqiu, Meng, Xianmin
Publicado 2020

Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance

por Huang, Peisen, Wang, Li, Li, Qing, Xu, Jun, Xu, Junyan, Xiong, Yuyan, Chen, Guihao, Qian, Haiyan, Jin, Chen, Yu, Yuan, Liu, Jiandong, Qian, Li, Yang, Yuejin
Publicado 2019

Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair

por Xiong, Yuyan, Tang, Ruijie, Xu, Junyan, Jiang, Wenyang, Gong, Zhaoting, Zhang, Lili, Li, Xiaosong, Ning, Yu, Huang, Peisen, Xu, Jun, Chen, Guihao, Jin, Chen, Li, Xiangdong, Qian, Haiyan, Yang, Yuejin
Publicado 2022

Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy

por Luo, Yuxuan, Jiang, Nan, May, Herman I., Luo, Xiang, Ferdous, Anwarul, Schiattarella, Gabriele G., Chen, Guihao, Li, Qinfeng, Li, Chao, Rothermel, Beverly A., Jiang, Dingsheng, Lavandero, Sergio, Gillette, Thomas G., Hill, Joseph A.
Publicado 2021

Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization by targeting mi...

por Ning, Yu, Huang, Peisen, Chen, Guihao, Xiong, Yuyan, Gong, Zhaoting, Wu, Chunxiao, Xu, Junyan, Jiang, Wenyang, Li, Xiaosong, Tang, Ruijie, Zhang, Lili, Hu, Mengjin, Xu, Jing, Xu, Jun, Qian, Haiyan, Jin, Chen, Yang, Yuejin
Publicado 2023

Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway

por Xiong, Yuyan, Tang, Ruijie, Xu, Junyan, Jiang, Wenyang, Gong, Zhaoting, Zhang, Lili, Ning, Yu, Huang, Peisen, Xu, Jun, Chen, Guihao, Li, Xiaosong, Hu, Mengjin, Xu, Jing, Wu, Chunxiao, Jin, Chen, Li, Xiangdong, Qian, Haiyan, Yang, Yuejin
Publicado 2022

Cardiomyocyte-derived small extracellular vesicles can signal eNOS activation in cardiac microvascular endothelial cells to protect against Ischemia/Reperfusion injury

por Chen, Guihao, Xu, Chuansheng, Gillette, Thomas G., Huang, Tongyi, Huang, Peisen, Li, Qing, Li, Xiangdong, Li, Qinfeng, Ning, Yu, Tang, Ruijie, Huang, Cunrong, Xiong, Yuyan, Tian, Xiaqiu, Xu, Jun, Xu, Junyan, Chang, Liping, Wei, Cong, Jin, Chen, Hill, Joseph A., Yang, Yuejin
Publicado 2020

China Tongxinluo Study for myocardial protection in patients with Acute Myocardial Infarction (CTS-AMI): Rationale and design of a randomized, double-blind, placebo-controlled, mul...

por Xu, Yi, Li, Xiangdong, Zhang, Haitao, Wu, Yuan, Zhang, Jun, Li, Jia, Dou, Kefei, Yan, Hongbing, You, Shijie, Yang, Yanmin, Liang, Yan, Xu, Lianjun, Gao, Xiaojin, Liu, Chen, Dong, Qiuting, Zhang, Wenjia, Song, Guangyuan, Zhang, Tao, Jiang, Lin, Chen, Guihao, Tang, Ruijie, Jin, Chen, Yang, Jingang, Yao, Chen, Xian, Ying, Peterson, Eric D., Gao, Runlin, Yang, Yuejin
Publicado 2020