SUN-751 RORγ Is a Master Regulator of Tumor Lipid Metabolism

por Chen, Hong-Wu
Publicado 2020

Natural compounds ursolic acid and digoxin exhibit inhibitory activities to cancer cells in RORγ-dependent and -independent manner

por Zou, Hongye, Yang, Yatian, Chen, Hong-Wu
Publicado 2023

Deregulation of Cholesterol Homeostasis by a Nuclear Hormone Receptor Crosstalk in Advanced Prostate Cancer

por Yang, Nianxin, Yang, Yatian, Huang, Zenghong, Chen, Hong-Wu
Publicado 2022

Improving Antibacterial Activity and Biocompatibility of Bioinspired Electrospinning Silk Fibroin Nanofibers Modified by Graphene Oxide

por Wang, Shu-Dong, Ma, Qian, Wang, Ke, Chen, Hong-Wu
Publicado 2018

Transporting Cells in Semi-Solid Gel Condition and at Ambient Temperature

por Wang, Junjian, Chen, Peng, Xu, Jianzhen, Zou, June.X, Wang, Haibin, Chen, Hong-Wu
Publicado 2015

MiR-520f promotes cell aggressiveness by regulating fibroblast growth factor 16 in hepatocellular carcinoma

por Xu, Feng Feng, Xie, Wen Feng, Zha, Guo Qing, Chen, Hong Wu, Deng, Liang
Publicado 2017

Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling

por Zhang, Xiong, Huang, Zenghong, Wang, Junjian, Ma, Zhao, Yang, Joy, Corey, Eva, Evans, Christopher P., Yu, Ai-Ming, Chen, Hong-Wu
Publicado 2021

Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer

por Chen, Yixin, Tu, Mei-Juan, Han, Fangwei, Liu, Zhenzhen, Batra, Neelu, Lara, Primo N., Chen, Hong-Wu, Bi, Huichang, Yu, Ai-Ming
Publicado 2023

Bivalirudin vs. heparin on a background of ticagrelor and aspirin in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention:...

por Yu, Xiao-Fan, Chen, Hong-Wu, Xu, Jie, Xu, Qi-Zhi, Zhang, Xiao-Hong, Li, Bin-Bin, Xu, Bang-Long, Ma, Li-Kun
Publicado 2022

Androgen receptor blockade resistance with enzalutamide in prostate cancer results in immunosuppressive alterations in the tumor immune microenvironment

por Xu, Pengfei, Yang, Joy C, Chen, Bo, Nip, Christopher, Van Dyke, Jonathan E, Zhang, Xiong, Chen, Hong-Wu, Evans, Christopher P, Murphy, William J, Liu, Chengfei
Publicado 2023

Discovery of a highly potent and orally available importin-β1 inhibitor that overcomes enzalutamide-resistance in advanced prostate cancer

por Huang, Jia-Luo, Yan, Xue-Long, Huang, Dong, Gan, Lu, Gao, Huahua, Fan, Run-Zhu, Li, Shen, Yuan, Fang-Yu, Zhu, Xinying, Tang, Gui-Hua, Chen, Hong-Wu, Wang, Junjian, Yin, Sheng
Publicado 2023

Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance

por Wang, Hong, Wang, Qianqian, Cai, Guodi, Duan, Zhijian, Nugent, Zoann, Huang, Jie, Zheng, Jianwei, Borowsky, Alexander D., Li, Jian Jian, Liu, Peiqing, Kung, Hsing-Jien, Murphy, Leigh, Chen, Hong-Wu, Wang, Junjian
Publicado 2022

Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer

por Liu, Chengfei, Lou, Wei, Yang, Joy C., Liu, Liangren, Armstrong, Cameron M., Lombard, Alan P., Zhao, Ruining, Noel, Onika D. V., Tepper, Clifford G., Chen, Hong-Wu, Dall’Era, Marc, Evans, Christopher P., Gao, Allen C.
Publicado 2018

CPT1A/2-Mediated FAO Enhancement—A Metabolic Target in Radioresistant Breast Cancer

por Han, Shujun, Wei, Ryan, Zhang, Xiaodi, Jiang, Nian, Fan, Ming, Huang, Jie Hunter, Xie, Bowen, Zhang, Lu, Miao, Weili, Butler, Ashley Chen-Ping, Coleman, Matthew A., Vaughan, Andrew T., Wang, Yinsheng, Chen, Hong-Wu, Liu, Jiankang, Li, Jian Jian
Publicado 2019

Activation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes

por Ning, Shu, Zhao, Jinge, Lombard, Alan P., D’Abronzo, Leandro S., Leslie, Amy R., Sharifi, Masuda, Lou, Wei, Liu, Chengfei, Yang, Joy C., Evans, Christopher P., Corey, Eva, Chen, Hong-Wu, Yu, Aiming, Ghosh, Paramita M., Gao, Allen C.
Publicado 2022

ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma

por Krakstad, Camilla, Tangen, Ingvild L., Hoivik, Erling A., Halle, Mari K., Berg, Anna, Werner, Henrica M., Ræder, Maria B., Kusonmano, Kanthida, Zou, June X., Øyan, Anne M., Stefansson, Ingunn, Trovik, Jone, Kalland, Karl-Henning, Chen, Hong-Wu, Salvesen, Helga B.
Publicado 2015

Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin

por Zheng, Jianwei, Wang, Junfeng, Wang, Qian, Zou, Hongye, Wang, Hong, Zhang, Zhenhua, Chen, Jianghe, Wang, Qianqian, Wang, Panxia, Zhao, Yueshan, Lu, Jing, Zhang, Xiaolei, Xiang, Songtao, Wang, Haibin, Lei, Jinping, Chen, Hong-Wu, Liu, Peiqing, Liu, Yonghong, Han, Fanghai, Wang, Junjian
Publicado 2020

ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer

por Wang, Junjian, Zou, June X., Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C., Louie, Maggie C., Borowsky, Alexander D., Gao, Allen C., Evans, Christopher P., Lam, Kit S., Xu, Jianzhen, Kung, Hsing-Jien, Evans, Ronald M., Xu, Yong, Chen, Hong-Wu
Publicado 2016

Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes

por Hsu, Sheng-Chieh, Chen, Chia-Lin, Cheng, Mei-Ling, Chu, Cheng-Ying, Changou, Chun A., Yu, Yen-Ling, Yeh, Shauh-Der, Kuo, Tse-Chun, Kuo, Cheng-Chin, Chuu, Chih-Pin, Li, Chien-Feng, Wang, Lu-Hai, Chen, Hong-Wu, Yen, Yun, Ann, David K., Wang, Hung-Jung, Kung, Hsing-Jien
Publicado 2021

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

por Cai, Demin, Wang, Junjian, Gao, Bei, Li, Jin, Wu, Feng, Zou, June X., Xu, Jianzhen, Jiang, Yuqian, Zou, Hongye, Huang, Zenghong, Borowsky, Alexander D., Bold, Richard J., Lara, Primo N., Li, Jian Jian, Chen, Xinbin, Lam, Kit S., To, Ka-Fai, Kung, Hsing-Jien, Fiehn, Oliver, Zhao, Ruqian, Evans, Ronald M., Chen, Hong-Wu
Publicado 2019