Reassessing the Role of APOBEC3G in Human Immunodeficiency Virus Type 1 Infection of Quiescent CD4+ T-Cells

por Kamata, Masakazu, Nagaoka, Yoshiko, Chen, Irvin S. Y.
Publicado 2009

Modeling large fluctuations of thousands of clones during hematopoiesis: The role of stem cell self-renewal and bursty progenitor dynamics in rhesus macaque

por Xu, Song, Kim, Sanggu, Chen, Irvin S. Y., Chou, Tom
Publicado 2018

Live Cell Monitoring of hiPSC Generation and Differentiation Using Differential Expression of Endogenous microRNAs

por Kamata, Masakazu, Liang, Min, Liu, Shirley, Nagaoka, Yoshiko, Chen, Irvin S. Y.
Publicado 2010

Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs

por Yan, Ming, Wen, Jing, Liang, Min, Lu, Yunfeng, Kamata, Masakazu, Chen, Irvin S. Y.
Publicado 2015

Characterization of A Bifunctional Synthetic RNA Aptamer and A Truncated Form for Ability to Inhibit Growth of Non-Small Cell Lung Cancer

por Wang, Hanlu, Qin, Meng, Liu, Rihe, Ding, Xinxin, Chen, Irvin S. Y., Jiang, Yongping
Publicado 2019

Efficient derivation of chimeric-antigen receptor-modified T(SCM) cells

por Kranz, Emiko, Kuhlmann, Charles J., Chan, Joshua, Kim, Patrick Y., Chen, Irvin S. Y., Kamata, Masakazu
Publicado 2022

Specific Elimination of Latently HIV-1 Infected Cells Using HIV-1 Protease-Sensitive Toxin Nanocapsules

por Wen, Jing, Yan, Ming, Liu, Yang, Li, Jie, Xie, Yiming, Lu, Yunfeng, Kamata, Masakazu, Chen, Irvin S. Y.
Publicado 2016

High-Throughput Screening of Effective siRNAs Using Luciferase-Linked Chimeric mRNA

por Pang, Shen, Pokomo, Lauren, Chen, Kevin, Kamata, Masakazu, Mao, Si-Hua, Zhang, Hong, Razi, Elliot, An, Dong Sung, Chen, Irvin S. Y.
Publicado 2014

CD3-immunotoxin mediated depletion of T cells in lymphoid tissues of rhesus macaques

por Wang, Lan, Suryawanshi, Gajendra W., Kim, Shihyoung, Guan, Xin, Bonifacino, Aylin C., Metzger, Mark E., Donahue, Robert E., Kim, Sanggu, Chen, Irvin S.Y.
Publicado 2023

RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice

por Shimizu, Saki, Ringpis, Gene-Errol, Marsden, Matthew D, Cortado, Ruth V, Wilhalme, Holly M, Elashoff, David, Zack, Jerome A, Chen, Irvin S Y, An, Dong Sung
Publicado 2015

Robust CAR-T memory formation and function via hematopoietic stem cell delivery

por Zhen, Anjie, Carrillo, Mayra A., Mu, Wenli, Rezek, Valerie, Martin, Heather, Hamid, Philip, Chen, Irvin S. Y., Yang, Otto O., Zack, Jerome A., Kitchen, Scott G.
Publicado 2021

Correction: Robust CAR-T memory formation and function via hematopoietic stem cell delivery

por Zhen, Anjie, Carrillo, Mayra A, Mu, Wenli, Rezek, Valerie, Martin, Heather, Hamid, Philip, Chen, Irvin S. Y., Yang, Otto O., Zack, Jerome A., Kitchen, Scott G.
Publicado 2021

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques

por Wen, Jing, Cheever, Tracy, Wang, Lan, Wu, Di, Reed, Jason, Mascola, John, Chen, Xuejun, Liu, Cuiping, Pegu, Amarendra, Sacha, Jonah B., Lu, Yunfeng, Haigwood, Nancy L., Chen, Irvin S. Y.
Publicado 2021

Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1

por Khamaikawin, Wannisa, Shimizu, Saki, Kamata, Masakazu, Cortado, Ruth, Jung, Yujin, Lam, Jennifer, Wen, Jing, Kim, Patrick, Xie, Yiming, Kim, Sanggu, Arokium, Hubert, Presson, Angela P., Chen, Irvin S.Y., An, Dong Sung
Publicado 2017

Stem cell–derived CAR T cells traffic to HIV reservoirs in macaques

por Barber-Axthelm, Isaac M., Barber-Axthelm, Valerie, Sze, Kai Yin, Zhen, Anjie, Suryawanshi, Gajendra W., Chen, Irvin S.Y., Zack, Jerome A., Kitchen, Scott G., Kiem, Hans-Peter, Peterson, Christopher W.
Publicado 2021

Longitudinal clonal tracking in humanized mice reveals sustained polyclonal repopulation of gene-modified human-HSPC despite vector integration bias

por Suryawanshi, Gajendra W., Arokium, Hubert, Kim, Sanggu, Khamaikawin, Wannisa, Lin, Samantha, Shimizu, Saki, Chupradit, Koollawat, Lee, YooJin, Xie, Yiming, Guan, Xin, Suryawanshi, Vasantika, Presson, Angela P., An, Dong-Sung, Chen, Irvin S. Y.
Publicado 2021

The clonal repopulation of HSPC gene modified with anti–HIV-1 RNAi is not affected by preexisting HIV-1 infection

por Suryawanshi, Gajendra W., Khamaikawin, Wannisa, Wen, Jing, Shimizu, Saki, Arokium, Hubert, Xie, Yiming, Wang, Eugene, Kim, Shihyoung, Choi, Hyewon, Zhang, Chong, Yu, Hannah, Presson, Angela P., Kim, Namshin, An, Dong-Sung, Chen, Irvin S. Y., Kim, Sanggu
Publicado 2020

Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates

por Qin, Meng, Wang, Lan, Wu, Di, Williams, Christopher K., Xu, Duo, Kranz, Emiko, Guo, Qi, Guan, Jiaoqiong, Vinters, Harry V., Lee, YooJin, Xie, Yiming, Luo, Yun, Sun, Guibo, Sun, Xiaobo, He, Zhanlong, Lu, Yunfeng, Kamata, Masakazu, Wen, Jing, Chen, Irvin S. Y.
Publicado 2020

Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice

por Ringpis, Gene-Errol E., Shimizu, Saki, Arokium, Hubert, Camba-Colón, Joanna, Carroll, Maria V., Cortado, Ruth, Xie, Yiming, Kim, Patrick Y., Sahakyan, Anna, Lowe, Emily L., Narukawa, Munetoshi, Kandarian, Fadi N., Burke, Bryan P., Symonds, Geoff P., An, Dong Sung, Chen, Irvin S. Y., Kamata, Masakazu
Publicado 2012

Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS

por Zhen, Anjie, Peterson, Christopher W., Carrillo, Mayra A., Reddy, Sowmya Somashekar, Youn, Cindy S., Lam, Brianna B., Chang, Nelson Y., Martin, Heather A., Rick, Jonathan W., Kim, Jennifer, Neel, Nick C., Rezek, Valerie K., Kamata, Masakazu, Chen, Irvin S. Y., Zack, Jerome A., Kiem, Hans-Peter, Kitchen, Scott G.
Publicado 2017