Thinking big with small molecules

por Mruk, Karen, Chen, James K.
Publicado 2015

Controlling Destiny through Chemistry: Small-Molecule Regulators of Cell Fate

por Firestone, Ari J., Chen, James K.
Publicado 2009

Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing

por Yamazoe, Sayumi, McQuade, Lindsey E., Chen, James K.
Publicado 2014

Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development

por Shestopalov, Ilya A., Pitt, Cameron L. W., Chen, James K.
Publicado 2012

In Vivo Imaging of Hedgehog Pathway Activation with a Nuclear Fluorescent Reporter

por Mich, John K., Payumo, Alexander Y., Rack, Paul G., Chen, James K.
Publicado 2014

Antisense Oligonucleotide Activation via Enzymatic Antibiotic Resistance Mechanism

por Darrah, Kristie E., Albright, Savannah, Kumbhare, Rohan, Tsang, Michael, Chen, James K., Deiters, Alexander
Publicado 2023

Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase

por Gutzman, Jennifer H., Graeden, Ellie, Brachmann, Isabel, Yamazoe, Sayumi, Chen, James K., Sive, Hazel
Publicado 2018

Tbx16 regulates hox gene activation in mesodermal progenitor cells

por Payumo, Alexander Y., McQuade, Lindsey E., Walker, Whitney J., Yamazoe, Sayumi, Chen, James K.
Publicado 2016

Ultrasensitive optical imaging with lanthanide lumiphores

por Cho, Ukrae, Riordan, Daniel P., Ciepla, Paulina, Kocherlakota, Kiranmai S., Chen, James K., Harbury, Pehr B.
Publicado 2017

Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage

por Yi, Jason, Wu, Xufeng, Chung, Andrew H., Chen, James K., Kapoor, Tarun M., Hammer, John A.
Publicado 2013

Hyaluronic acid synthesis is required for zebrafish tail fin regeneration

por Ouyang, Xiaohu, Panetta, Nicholas J., Talbott, Maya D., Payumo, Alexander Y., Halluin, Caroline, Longaker, Michael T., Chen, James K.
Publicado 2017

ORC1 BAH domain links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome

por Kuo, Alex J., Song, Jikui, Cheung, Peggie, Ishibe-Murakami, Satoko, Yamazoe, Sayumi, Chen, James K., Patel, Dinshaw J., Gozani, Or
Publicado 2012

Structure-activity mapping of ARHGAP36 reveals regulatory roles for its GAP homology and C-terminal domains

por Nano, Patricia R., Johnson, Taylor K., Kudo, Takamasa, Mooney, Nancie A., Ni, Jun, Demeter, Janos, Jackson, Peter K., Chen, James K.
Publicado 2021

Versatile Synthesis and Rational Design of Caged Morpholinos

por Ouyang, Xiaohu, Shestopalov, Ilya A., Sinha, Surajit, Zheng, Genhua, Pitt, Cameron L. W., Li, Wen-Hong, Olson, Andrew J., Chen, James K.
Publicado 2009

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

por Firestone, Ari J., Weinger, Joshua S., Maldonado, Maria, Barlan, Kari, Langston, Lance D., O'Donnell, Michael, Gelfand, Vladimir I., Kapoor, Tarun M., Chen, James K.
Publicado 2012

Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator

por Hwang, Sunhee, Mruk, Karen, Rahighi, Simin, Raub, Andrew G., Chen, Che-Hong, Dorn, Lisa E., Horikoshi, Naoki, Wakatsuki, Soichi, Chen, James K., Mochly-Rosen, Daria
Publicado 2018

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

por Breslow, David K., Hoogendoorn, Sascha, Kopp, Adam R., Morgens, David W., Vu, Brandon K., Kennedy, Margaret C., Han, Kyuho, Li, Amy, Hess, Gaelen T., Bassik, Michael C., Chen, James K., Nachury, Maxence V.
Publicado 2018

Direct kinetochore–spindle pole connections are not required for chromosome segregation

por Sikirzhytski, Vitali, Magidson, Valentin, Steinman, Jonathan B., He, Jie, Le Berre, Maël, Tikhonenko, Irina, Ault, Jeffrey G., McEwen, Bruce F., Chen, James K., Sui, Haixin, Piel, Matthieu, Kapoor, Tarun M., Khodjakov, Alexey
Publicado 2014

Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

por Wong, Wing Tak, Matrone, Gianfranco, Tian, XiaoYu, Tomoiaga, Simion Alin, Au, Kin Fai, Meng, Shu, Yamazoe, Sayumi, Sieveking, Daniel, Chen, Kaifu, Burns, David M, Chen, James K, Blau, Helen M, Cooke, John P
Publicado 2017

HIPK4 is essential for murine spermiogenesis

por Crapster, J Aaron, Rack, Paul G, Hellmann, Zane J, Le, Austen D, Adams, Christopher M, Leib, Ryan D, Elias, Joshua E, Perrino, John, Behr, Barry, Li, Yanfeng, Lin, Jennifer, Zeng, Hong, Chen, James K
Publicado 2020