Selene: a PyTorch-based deep learning library for sequence data

por Chen, Kathleen M., Cofer, Evan M., Zhou, Jian, Troyanskaya, Olga G.
Publicado 2019

A sequence-based global map of regulatory activity for deciphering human genetics

por Chen, Kathleen M., Wong, Aaron K., Troyanskaya, Olga G., Zhou, Jian
Publicado 2022

PathCORE-T: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia

por Chen, Kathleen M., Tan, Jie, Way, Gregory P., Doing, Georgia, Hogan, Deborah A., Greene, Casey S.
Publicado 2018

Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk

por Zhou, Jian, Theesfeld, Chandra L., Yao, Kevin, Chen, Kathleen M., Wong, Aaron K., Troyanskaya, Olga G.
Publicado 2018

Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk

por Park, Christopher Y., Zhou, Jian, Wong, Aaron K., Chen, Kathleen M., Theesfeld, Chandra L., Darnell, Robert B., Troyanskaya, Olga G.
Publicado 2021

Genomic analyses implicate noncoding de novo variants in congenital heart disease

por Richter, Felix, Morton, Sarah U., Won Kim, Seong, Kitaygorodsky, Alexander, Wasson, Lauren K., Chen, Kathleen M., Zhou, Jian, Qi, Hongjian, Patel, Nihir, DePalma, Steven R., Parfenov, Michael, Homsy, Jason, Gorham, Joshua M., Manheimer, Kathryn B., Velinder, Matthew, Farrell, Andrew, Marth, Gabor, Schadt, Eric E., Kaltman, Jonathan R., Newburger, Jane W., Giardini, Alessandro, Goldmuntz, Elizabeth, Brueckner, Martina, Kim, Richard, Porter, George A., Bernstein, Daniel, Chung, Wendy K., Srivastava, Deepak, Tristani-Firouzi, Martin, Troyanskaya, Olga G., Dickel, Diane E., Shen, Yufeng, Seidman, Jonathan G., Seidman, Christine E., Gelb, Bruce D.
Publicado 2020