How do amino acid substitutions affect the amyloidogenic properties and seeding efficiency of prion peptides

por Chuang, Chi-Chen, Liao, Tai-Yan, Chen, Eric H.-L, Chen, Rita P.-Y.
Publicado 2013

Self-Replication of Prion Protein Fragment 89-230 Amyloid Fibrils Accelerated by Prion Protein Fragment 107-143 Aggregates

por Sneideris, Tomas, Ziaunys, Mantas, Chu, Brett K.-Y., Chen, Rita P.-Y., Smirnovas, Vytautas
Publicado 2020

Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer’s disease

por Chen, Po-Ting, Chen, Zih-ten, Hou, Wen-Chi, Yu, Lung-Chih, Chen, Rita P.-Y.
Publicado 2016

Slow spontaneous α-to-β structural conversion in a non-denaturing neutral condition reveals the intrinsically disordered property of the disulfide-reduced recombinant mouse prion p...

por Sang, Jason C., Lee, Chung-Yu, Luh, Frederick Y., Huang, Ya-Wen, Chiang, Yun-Wei, Chen, Rita P.-Y.
Publicado 2012

Directly monitor protein rearrangement on a nanosecond-to-millisecond time-scale

por Chen, Eric H.-L., Lu, Tony T.-Y., Hsu, Jack C.-C., Tseng, Yufeng Jane, Lim, T.-S., Chen, Rita P.-Y.
Publicado 2017

Amyloid Core Formed of Full-Length Recombinant Mouse Prion Protein Involves Sequence 127–143 but Not Sequence 107–126

por Chatterjee, Biswanath, Lee, Chung-Yu, Lin, Chen, Chen, Eric H.-L., Huang, Chao-Li, Yang, Chien-Chih, Chen, Rita P.-Y.
Publicado 2013

Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme

por Chen, Po-Ting, Chen, Chao-Long, Lin, Lilian Tsai-Wei, Lo, Chun-Hsien, Hu, Chaur-Jong, Chen, Rita P.-Y., Wang, Steven S.-S.
Publicado 2016

Synthesis and Biological Evaluation of Hydroxylated Monocarbonyl Curcumin Derivatives as Potential Inducers of Neprilysin Activity

por Matiadis, Dimitris, Ng, See-Ting, Chen, Eric H.-L., Nigianni, Georgia, Vidali, Veroniki P., Canko, Aleksander, Chen, Rita P.-Y., Sagnou, Marina
Publicado 2021

De Novo Design of Antimicrobial Peptides With a Special Charge Pattern and Their Application in Combating Plant Pathogens

por Chen, Eric H. -L., Weng, Cheng-Wei, Li, Yi-Min, Wu, Ming-Chin, Yang, Chien-Chih, Lee, Kung-Ta, Chen, Rita P. -Y., Cheng, Chiu-Ping
Publicado 2021

Visualizing the membrane disruption action of antimicrobial peptides by cryo-electron tomography

por Chen, Eric H.-L., Wang, Chun-Hsiung, Liao, Yi-Ting, Chan, Feng-Yueh, Kanaoka, Yui, Uchihashi, Takayuki, Kato, Koichi, Lai, Longsheng, Chang, Yi-Wei, Ho, Meng-Chiao, Chen, Rita P.-Y.
Publicado 2023

An intranasally delivered peptide drug ameliorates cognitive decline in Alzheimer transgenic mice

por Cheng, Yu‐Sung, Chen, Zih‐ten, Liao, Tai‐Yan, Lin, Chen, Shen, Howard C‐H, Wang, Ya‐Han, Chang, Chi‐Wei, Liu, Ren‐Shyan, Chen, Rita P‐Y, Tu, Pang‐hsien
Publicado 2017

A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter baumannii

por Chen, Sung-Pang, Chen, Eric H-L, Yang, Sheng-Yung, Kuo, Pin-Shin, Jan, Hau-Ming, Yang, Tsai-Chen, Hsieh, Ming-Yen, Lee, Kung-Ta, Lin, Chun-Hung, Chen, Rita P-Y
Publicado 2021

Corrigendum: A Systematic Study of the Stability, Safety, and Efficacy of the de novo Designed Antimicrobial Peptide PepD2 and Its Modified Derivatives Against Acinetobacter bauman...

por Chen, Sung-Pang, Chen, Eric H-L, Yang, Sheng-Yung, Kuo, Pin-Shin, Jan, Hau-Ming, Yang, Tsai-Chen, Hsieh, Ming-Yen, Lee, Kung-Ta, Lin, Chun-Hung, Chen, Rita P-Y
Publicado 2022

Cholesterol twists the transmembrane Di-Gly region of amyloid-precursor protein

por Wang, David Tzu-Wei, Tang, Tiffany Y C, Kuo, Chun-Ting, Yu, Yun-Ting, Chen, Eric H L, Lee, Ming-Tao, Tsai, Ruei-Fong, Chen, Hung-Ying, Chiang, Yun-Wei, Chen, Rita P Y
Publicado 2023