Proximal binding of dCas9 at a DNA double strand break stimulates homology-directed repair as a local inhibitor of classical non-homologous end joining

por Feng, Yi-Li, Liu, Si-Cheng, Chen, Ruo-Dan, Sun, Xiu-Na, Xiao, Jing-Jing, Xiang, Ji-Feng, Xie, An-Yong
Publicado 2023

DNA nicks induce mutational signatures associated with BRCA1 deficiency

por Feng, Yi-Li, Liu, Qian, Chen, Ruo-Dan, Liu, Si-Cheng, Huang, Zhi-Cheng, Liu, Kun-Ming, Yang, Xiao-Ying, Xie, An-Yong
Publicado 2022

Target residence of Cas9-sgRNA influences DNA double-strand break repair pathway choices in CRISPR/Cas9 genome editing

por Liu, Si-Cheng, Feng, Yi-Li, Sun, Xiu-Na, Chen, Ruo-Dan, Liu, Qian, Xiao, Jing-Jing, Zhang, Jin-Na, Huang, Zhi-Cheng, Xiang, Ji-Feng, Chen, Guo-Qiao, Yang, Yi, Lou, Chao, Li, Hao-Dan, Cai, Zhen, Xu, Shi-Ming, Lin, Hui, Xie, An-Yong
Publicado 2022