Population pharmacokinetic analysis of sparsentan in healthy volunteers and patients with focal segmental glomerulosclerosis

por Wada, Russell, Kleijn, Huub Jan, Zhang, Lu, Chen, Shang‐Chiung
Publicado 2023

Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody‐Drug Conjugates

por Li, Chunze, Chen, Shang‐Chiung, Chen, Yuan, Girish, Sandhya, Kågedal, Matts, Lu, Dan, Lu, Tong, Samineni, Divya, Jin, Jin Y.
Publicado 2020

Clinical pharmacology of vc-MMAE antibody–drug conjugates in cancer patients: learning from eight first-in-human Phase 1 studies

por Li, Chunze, Zhang, Cindy, Li, Zao, Samineni, Divya, Lu, Dan, Wang, Bei, Chen, Shang-Chiung, Zhang, Rong, Agarwal, Priya, Fine, Bernard M., Girish, Sandhya
Publicado 2019

A phase I study of pharmacokinetics of trastuzumab emtansine in Chinese patients with locally advanced inoperable or metastatic human epidermal growth factor receptor 2-positive br...

por Ji, Dongmei, Shen, Weina, Zhang, Jian, Cao, Junning, Li, Wenhua, Lam, Lisa H., Wu, Fan, Wang, Bei, Li, Zao, Sun, Guofang, Hu, Xichun, Chen, Shang-Chiung
Publicado 2020

Prediction of Human Pharmacokinetics of Antibody–Drug Conjugates From Nonclinical Data

por Li, Chunze, Zhang, Cindy, Deng, Rong, Leipold, Douglas, Li, Dongwei, Latifi, Brandon, Gao, Yuying, Zhang, Crystal, Li, Zao, Miles, Dale, Chen, Shang‐Chiung, Samineni, Divya, Wang, Bei, Agarwal, Priya, Lu, Dan, Prabhu, Saileta, Girish, Sandhya, Kamath, Amrita V.
Publicado 2019

First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

por Kim, Tae Won, Burris, Howard A., de Miguel Luken, Maria J., Pishvaian, Michael J., Bang, Yung-Jue, Gordon, Michael, Awada, Ahmad, Camidge, D. Ross, Hodi, F. Stephen, McArthur, Grant A., Miller, Wilson H., Cervantes, Andres, Chow, Laura Q., Lesokhin, Alexander M., Rutten, Annemie, Sznol, Mario, Rishipathak, Deepali, Chen, Shang-Chiung, Stefanich, Eric, Pourmohamad, Tony, Anderson, Maria, Kim, Jeong, Huseni, Mahrukh, Rhee, Ina, Siu, Lillian L.
Publicado 2022